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Santa Cruz Vacation Rentals

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Check prices for these dates

Tonight
Dec 29 - Dec 30
Tomorrow
Dec 30 - Dec 31
This weekend
Jan 2 - Jan 4
Next weekend
Jan 9 - Jan 11

Our top choices for Santa Cruz vacation rentals

1 bedroom, laptop workspace, free WiFi
Colchagua Tiny Lodge

Colchagua Tiny Lodge

Colchagua Tiny Lodge
3.0 star property
Santa Cruz
10.0 out of 10, Exceptional, (5)
"The Tiny Lodge has so many amenities thoughtfully packed into a cozy package. Loved the thought put into surfaces and spaces to sit your personal belongings. The bed is luxurious. 10 out of 10. "
United States
Trisha
The price is ￥31,933
￥31,933 total
Jan 14 - Jan 15, 2026
Colchagua Tiny Lodge
Property grounds
The ambush. Field and comfort

The ambush. Field and comfort

The ambush. Field and comfort
Santa Cruz
The price is ￥23,039
￥30,734 total
Dec 30 - Dec 31
The ambush. Field and comfort
Outdoor pool
Beautiful 5-bedroom home near Santa Cruz perfect for your getaway

Beautiful 5-bedroom home near Santa Cruz perfect for your getaway

Beautiful 5-bedroom home near Santa Cruz perfect for your getaway
2.5 star property
Santa Cruz
The price is ￥62,960
￥71,807 total
Jan 6 - Jan 7, 2026
Beautiful 5-bedroom home near Santa Cruz perfect for your getaway
Exterior
Refugio Campestre, Cabaña con Tinaja (Cabin with Tinaja)

Refugio Campestre, Cabaña con Tinaja (Cabin with Tinaja)

Refugio Campestre, Cabaña con Tinaja (Cabin with Tinaja)
2.0 star property
Chimbarongo
The price is ￥7,649
￥10,967 total
Jan 5 - Jan 6, 2026
Refugio Campestre, Cabaña con Tinaja (Cabin with Tinaja)
Property grounds
Corazon de Colchagua Sta Cruz Cabin

Corazon de Colchagua Sta Cruz Cabin

Corazon de Colchagua Sta Cruz Cabin
Nancagua
The price is ￥9,215
￥12,993 total
Dec 30 - Dec 31
Corazon de Colchagua Sta Cruz Cabin
Dining
House in a natural setting

House in a natural setting

House in a natural setting
Curico
The price is ￥11,427
￥16,916 total
Jan 5 - Jan 6, 2026
House in a natural setting
Living area
The most comfortable apartment in San Fernando

The most comfortable apartment in San Fernando

The most comfortable apartment in San Fernando
San Fernando
The price is ￥12,938
￥21,785 total
Jan 1 - Jan 2, 2026
The most comfortable apartment in San Fernando
Exterior detail
Hostel Turismo San Vicente Tagua Tagua

Hostel Turismo San Vicente Tagua Tagua

Hostel Turismo San Vicente Tagua Tagua
San Vicente de Taguatagua
The price is ￥8,478
￥12,533 total
Dec 30 - Dec 31
Hostel Turismo San Vicente Tagua Tagua
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz Hotel Reviews

TerraViña

TerraViña

10/10 Excellent
"Clean and spacious suite, fantastic staff and service and very picturesque location"
Rahul 2-night trip
Posted 7 days ago
TerraViña

Find out more about Santa Cruz

Search for holiday rentals in Santa Cruz on Expedia! You can easily find your home rentals, villas, holiday apartments in Santa Cruz using one of the methods below:

  • View our selection of featured holiday rentals in Santa Cruz
  • Use the map to find apartments and other holiday homes in the Santa Cruz neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Santa Cruz while they last

Look no further and take a look at our great range of rental properties in Santa Cruz!

Frequently asked questions

Can I find a vacation rental in Santa Cruz?

Yes, there are vacation rentals in Santa Cruz close to Colchagua Campo y Vino, or you can choose a more secluded option if you want a relaxing stay. Our travelers say Santa Cruz has a good selection of wineries and the restaurants. Make sure you have time to check out the local tours and casinos during your trip.

What's the top vacation rental that Santa Cruz has to offer?

Hosteria No me Olvides: This vacation home rental outside Santa Cruz offers a terrace and cable TV to help you feel comfortable in your new surroundings. Our travelers also rate The ambush. Field and comfort as a favorite home for rent in Santa Cruz.

What can I see and do in Santa Cruz?

Cultural attractions include Museo de Colchagua, whereas Millahue Valley is a spot to enjoy nature. Casino Colchagua and Colchagua Campo y Vino are other places to visit while you're in town.

What are vacation rentals like in Santa Cruz?

Vacation rentals are private properties you can stay in for several days or longer in Santa Cruz. Vacation rentals feature amenities such as patios, hot tubs, and fire pits so you'll feel just like you're staying in your own home. If you're concerned about a clean environment, a vacation rental can offer a sense of safety away from shared hotel elevators and busy lobbies while still allowing you the experience of travel. You'll also find more space in a vacation rental than in a hotel, which makes a vacation rental a popular option for a family getaway.