Santa Cruz Vacation Rentals

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
Feb 27 - Mar 1
In two months
Apr 10 - Apr 12
In three months
May 8 - May 10
In four months
Jun 5 - Jun 7

Our top choices for Santa Cruz vacation rentals

1 bedroom, laptop workspace, free WiFi

Colchagua Tiny Lodge

Colchagua Tiny Lodge
3.0 star property
Santa Cruz
9.8 out of 10, Exceptional, (7 reviews)
"The Tiny Lodge has so many amenities thoughtfully packed into a cozy package. Loved the thought put into surfaces and spaces to sit your personal belongings. The bed is luxurious. 10 out of 10. "
United States
Trisha
The price is ￥32,951
￥32,951 total
Feb 25 - Feb 26
Colchagua Tiny Lodge
Exterior

The ambush. Field and comfort

The ambush. Field and comfort
Santa Cruz
The price is ￥22,666
￥30,237 total
Feb 21 - Feb 22
The ambush. Field and comfort
Terrace/patio

Corazon de Colchagua Sta Cruz Cabin

Corazon de Colchagua Sta Cruz Cabin
Nancagua
The price is ￥9,066
￥12,783 total
Feb 19 - Feb 20
Corazon de Colchagua Sta Cruz Cabin
Dining

House in a natural setting

House in a natural setting
Curico
The price is ￥11,242
￥16,642 total
Feb 21 - Feb 22
House in a natural setting
Outdoor pool

Beautiful 5-bedroom home near Santa Cruz perfect for your getaway

Beautiful 5-bedroom home near Santa Cruz perfect for your getaway
Santa Cruz
The price is ￥62,162
￥72,353 total
Feb 15 - Feb 16
Beautiful 5-bedroom home near Santa Cruz perfect for your getaway
Property grounds

Hostel Turismo San Vicente Tagua Tagua

Hostel Turismo San Vicente Tagua Tagua
San Vicente de Taguatagua
The price is ￥8,341
￥12,330 total
Feb 14 - Feb 15
Hostel Turismo San Vicente Tagua Tagua
Interior

Refugio Campestre, Cabaña con Tinaja (Cabin with Tinaja)

Refugio Campestre, Cabaña con Tinaja (Cabin with Tinaja)
Chimbarongo
The price is ￥7,833
￥11,097 total
Feb 19 - Feb 20
Refugio Campestre, Cabaña con Tinaja (Cabin with Tinaja)
3 bedrooms, iron/ironing board, WiFi, bed sheets

The most comfortable apartment in San Fernando

The most comfortable apartment in San Fernando
San Fernando
The price is ￥12,729
￥21,433 total
Feb 24 - Feb 25
The most comfortable apartment in San Fernando
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Santa Cruz Hotel Reviews

Santa Cruz Plaza

Santa Cruz Plaza

10/10 Excellent
"Very clean and staff very courteous "
Ivette 3-night trip
Posted 9 days ago
Santa Cruz Plaza

Find out more about Santa Cruz

Search for holiday rentals in Santa Cruz on Expedia! You can easily find your home rentals, villas, holiday apartments in Santa Cruz using one of the methods below:

  • View our selection of featured holiday rentals in Santa Cruz
  • Use the map to find apartments and other holiday homes in the Santa Cruz neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Santa Cruz while they last

Look no further and take a look at our great range of rental properties in Santa Cruz!

Frequently asked questions

Can I find a vacation rental in Santa Cruz?

Yes, there are vacation rentals in Santa Cruz close to Colchagua Campo y Vino, or you can choose a more secluded option if you want a relaxing stay. Our travelers say Santa Cruz has a good selection of wineries and the restaurants. Make sure you have time to check out the local tours and casinos during your trip.

What's the top vacation rental that Santa Cruz has to offer?

Hosteria No me Olvides: This vacation home rental outside Santa Cruz offers a terrace and cable TV to help you feel comfortable in your new surroundings. Our travelers also rate The ambush. Field and comfort as a favorite home for rent in Santa Cruz.

What can I see and do in Santa Cruz?

Cultural attractions include Museo de Colchagua, whereas Millahue Valley is a spot to enjoy nature. Casino Colchagua and Colchagua Campo y Vino are other places to visit while you're in town.

What are vacation rentals like in Santa Cruz?

Vacation rentals are private properties you can stay in for several days or longer in Santa Cruz. Vacation rentals feature amenities such as patios, hot tubs, and fire pits so you'll feel just like you're staying in your own home. If you're concerned about a clean environment, a vacation rental can offer a sense of safety away from shared hotel elevators and busy lobbies while still allowing you the experience of travel. You'll also find more space in a vacation rental than in a hotel, which makes a vacation rental a popular option for a family getaway.