Find 4 Star Hotels in Mesopotamia from ￥8,400
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Mesopotamia 4 Star Hotels
Compare Mesopotamia 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.
Amérian Hotel Casino Gala
Resistencia
9.0 out of 10, Wonderful, (165)
"Good check in"
Paul
Esplendor by Wyndham Savoy Rosario
Rosario Centro
8.6 out of 10, Excellent, (443)
"Excellent hotel Everything very comfortable, and convenient"
Cecilia Marina
The price is ￥13,119
￥13,119 total
Jan 2 - Jan 3, 2026
Marriott Corrientes Hotel
Corrientes
10.0 out of 10, Exceptional, (3)
"Very nice hotel"
Jeffrey
The price is ￥18,380
￥18,380 total
Dec 20 - Dec 21
Dazzler by Wyndham Rosario
Rosario
8.8 out of 10, Excellent, (187)
"Convenient if you like shopping and the hotel very good amenities "
Daniela
The price is ￥12,740
￥12,740 total
Dec 3 - Dec 4
InterTower Hotel
Santa Fe
8.8 out of 10, Excellent, (210)
"Excelent place to stay."
Angel
The price is ￥13,491
￥13,491 total
Dec 21 - Dec 22
Puerto Norte Design Hotel
Rosario
9.2 out of 10, Wonderful, (142)
"Super comfortable and luxurious with amazing view of the river. The staff was courteous enough and parking was easy and right in front of the hotel. "
Katie
The price is ￥19,287
￥19,287 total
Dec 5 - Dec 6
Los Silos Hotel
Santa Fe
9.2 out of 10, Wonderful, (27)
"Unique, interesting, and very nice. Staff was outstanding. We will be back soon"
Russell
The price is ￥17,983
￥17,983 total
Dec 21 - Dec 22
Pullman Rosario City Center Hotel
Rosario
8.6 out of 10, Excellent, (272)
"Nice"
juan
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 5-star hotels
Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Mesopotamia.
Bagú Urbano
Bolivar 2176 Posadas Misiones
8.4/10 Very Good! (343 reviews)
Still don't see what you're looking for?
See all properties in Mesopotamia.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Mesopotamia
The awe-inspiring Iguazú Falls is the centerpiece attraction of this northeastern Argentine region, which also hosts the country’s biggest carnival celebration.
Top Mesopotamia Hotel Reviews
Amérian Hotel Casino Gala
10/10 Excellent
Explore a world of travel with Expedia
Mesopotamia Hotels by Star Rating
More Hotel Options in Mesopotamia
- Adults Only Resorts & Hotels in Mesopotamia
- Adventure Hotels in Mesopotamia
- All-inclusive Hotel in Mesopotamia
- Beach Hotels in Mesopotamia
- Boutique Hotels in Mesopotamia
- Business Hotels in Mesopotamia
- Casinos in Mesopotamia
- Cheap Hotels in Mesopotamia
- Family Hotels in Mesopotamia
- Gay friendly Hotels in Mesopotamia
- Golf Hotels in Mesopotamia
- Green Hotels in Mesopotamia
- Historic Hotels in Mesopotamia
- Hotel Wedding Venues in Mesopotamia
- Hotel with a Concierge in Mesopotamia
- Hotels with Bars in Mesopotamia
- Hotels with Free Parking in Mesopotamia
- Hotels with Hot Tubs in Mesopotamia
- Hotels with Waterslides in Mesopotamia
- Hotels with WiFi in Mesopotamia
- Hotels with a Lazy River in Mesopotamia
- Hotels with a Pool in Mesopotamia
- Hotels with an Indoor Pool in Mesopotamia
- Hotels with smoking rooms in Mesopotamia
- Luxury Hotels in Mesopotamia
- Pet-friendly Hotels in Mesopotamia
- Resorts & Hotels with Spas in Mesopotamia
- Romantic Hotels in Mesopotamia
- Shopping Hotels in Mesopotamia
- Waterpark Hotels in Mesopotamia
More Accommodation Types in Mesopotamia
- Apartments in Mesopotamia
- Vacation Homes in Mesopotamia
- Aparthotels in Mesopotamia
- Cabin Rentals in Mesopotamia
- Lodges in Mesopotamia
- Hostels in Mesopotamia
- Guest Houses in Mesopotamia
- Farmstay in Mesopotamia
- B&B in Mesopotamia
- Condo Rentals in Mesopotamia
- Cottages in Mesopotamia
- Inns in Mesopotamia
- Villas in Mesopotamia
- Condo Resorts in Mesopotamia
- Resorts in Mesopotamia
- Castles in Mesopotamia
- Safari Tentalow in Mesopotamia
Explore more hotels
- Holiday Inn Express Rosario by IHG
- Holiday Inn Rosario by IHG
- Days Inn by Wyndham Zarate
- Amérian Hotel Casino Gala
- Howard Johnson Plaza La Ribera
- Howard Johnson by Wyndham Rosario
- Esplendor by Wyndham Savoy Rosario
- Puerto Norte Design Hotel
- BAGU URBANO
- Hotel Solans Riviera
- Pullman Rosario City Center Hotel
- Innovo
- Hotel Maitei Posadas
More ways to book
Expedia's Latest Trends
Hotels
- The Grand Residence Hotel Tenjin
- ALFIT HOTEL & BAR AKASAKA
- KADA beach glamping resora RAINBOW
- Hotel Niwa Tokyo
- Hotels near Oppama Station
- Dormy Inn Fukui Natural Hot Springs
- Center Hotel Narita 2 R51
- Hotels in Nuremberg
- Mövenpick Hotel Stuttgart Airport
- Capsule Hotels Odaiba
- Hotel MyStays Otemae
- Lohas Villa - Hostel
Flights
Packages