Upstate South Carolina Romantic Vacations 2026

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Top Romantic Upstate South Carolina Hotels

Relax on the shore of Lake Hartwell in our Fair Play retreat

Fair Play SC

34 min drive from Clemson University

Book a stay at this business-friendly vacation home in Fair Play. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Lake Hartwell and Glenn ...

9.8/10 Exceptional! (236 reviews)

"Everything was great."

Reviewed on Jan 10, 2026

Fall fun at the cabin! Convenient to Lake Keowee and Clemson

Seneca SC

22 min drive from Clemson University

Enjoy a stay at this romantic cabin, featuring a garden and in-room fireplaces for couples to enjoy.

9/10 Wonderful! (89 reviews)

"Great location for extra guests staying over in adjacent area. Really only used for sleeping. Did not use tvs, WiFi, or kitchen. Convenient check-in process."

Reviewed on Jul 19, 2026

Peaceful Oasis Convenient to Greenville!

Simpsonville SC

2 hours drive from Clemson University

Stay at this vacation home in Simpsonville. Enjoy a water park, a garden, and laundry facilities. Popular attractions Haywood Mall and Frankie's Fun Park are ...

10/10 Exceptional! (115 reviews)

"Pet friendly"

Reviewed on May 24, 2026

See all 3,061 properties in Upstate South Carolina

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.