
Eastern South Dakota Pet-friendly Vacations
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Top Pet-friendly Eastern South Dakota Hotels

La Quinta Inn & Suites by Wyndham Sioux Falls
4521 W. 41st Street Sioux Falls SD
- 9 min drive from Denny Sanford Premier Center
Dogs and cats may join you (for a fee) during your stay at this pet-friendly hotel. Take the opportunity to stretch your legs on the nearby hiking or biking ...
9.2/10 Wonderful! (1,491 reviews)
"Hotel was nice. Lady at front desk when I checked in never looked up or said anything, nothing. Guy came from back to help me. When I left same old rude lady said she couldn't give me a receipt so told her thats wasnt true then she said you don't have to be rude about it. So I told her she needed ..."
Reviewed on Sep 14, 2026

Econo Lodge Sioux Falls Empire Mall
3500 Gateway Boulevard Sioux Falls SD
- 9 min drive from Denny Sanford Premier Center
This pet-friendly hotel welcomes dogs and cats (fees apply).
7/10 Good! (442 reviews)
Economy hotel, no thrills, but it's nice
"Staff was really nice. Rooms are spacious. Good value and convenient to many stores/restaurants, etc. Rooms for clean."
Reviewed on Oct 18, 2022

Kelly Inn & Suites Mitchell South Dakota
1010 Cabela Drive Mitchell SD
- 3 hours drive from Denny Sanford Premier Center
This pet-friendly hotel welcomes dogs for free.
7.8/10 Good! (1,082 reviews)
"Clean rooms very helpful staff. Great location"
Reviewed on Sep 14, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
