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Top Pet-friendly South Carolina Midlands Hotels

La Quinta Inn & Suites by Wyndham Florence

2123 W Lucas St Florence SC

3 hours drive from Fort Jackson

This pet-friendly hotel welcomes dogs and cats (fees apply).

7.8/10 Good! (1,674 reviews)

Have stayed here often. Always clean and courteous.

Reviewed on Dec 4, 2025

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

7333 Garners Ferry Rd Columbia SC

9 min drive from Fort Jackson

This pet-friendly hotel welcomes dogs and cats (fees apply).

7.6/10 Good! (1,017 reviews)

Nice clean and updated room.

Reviewed on Nov 24, 2025

Hampton Inn Columbia I-26/Harbison Blvd.

101 Woodcross Dr Columbia SC

31 min drive from Fort Jackson

Hiking and biking trails are ready for you to explore near this lakefront hotel, where dogs and cats can stay for an additional fee.

9/10 Wonderful! (1,000 reviews)

Room was clean, staff friendly

Reviewed on Nov 30, 2025

See all 3,058 properties in South Carolina Midlands

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.