Southwest Minnesota Luxury Vacations

Book a Luxury Hotel + Flight or Car together to unlock savings

Photo by Samantha Baker
  • Plan, book, travel with confidence

  • Better together

    Save up to ¥45,448 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Top Luxury Southwest Minnesota Hotels

AmericInn by Wyndham Blue Earth

AmericInn by Wyndham Blue Earth

2 out of 5
1495 Domes Dr Blue Earth MN
  • 1 hour drive from Mayo Clinic Health System Event Center
Go for a luxurious stay at AmericInn by Wyndham Blue Earth, where you can enjoy amenities like 24-hour room service, premium channels, and more. Deluxe amenities ...
7.8/10 Good! (458 reviews)
All good.

Reviewed on Dec 5, 2025

AmericInn by Wyndham Blue Earth
Super 8 by Wyndham Jackson MN

Super 8 by Wyndham Jackson MN

2 out of 5
2025 Highway 71 N Jackson MN
  • 3 hours drive from Mayo Clinic Health System Event Center
Indulge yourself with classy lodging at Super 8 by Wyndham Jackson MN, where you'll enjoy amenities like premium channels and more.
8/10 Very Good! (600 reviews)
Enjoyed my stay

Reviewed on Nov 28, 2025

Super 8 by Wyndham Jackson MN
Days Inn by Wyndham Mankato

Days Inn by Wyndham Mankato

2 out of 5
1285 Range St Mankato MN
  • 4 min drive from Mayo Clinic Health System Event Center
Discover luxurious lodging at Days Inn by Wyndham Mankato, where you can enjoy amenities like premium channels, flat-screen TVs, and more. Deluxe amenities at ...
6.6/10 (839 reviews)
Friendly staff, very clean, nice hot tub and pool

Reviewed on Dec 12, 2025

Days Inn by Wyndham Mankato
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.