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Top Luxury Southeastern Indiana Hotels

21c Museum Hotel Louisville

700 W Main Street Louisville KY

9 min walk from KFC Yum Center

21c Museum Hotel Louisville is one of the Louisville luxury 4.5-star boutique properties where you can treat yourself to Champagne service, massage services, ...

9.4/10 Exceptional! (1,001 reviews)

Everything in gift shop dusty. Receptionist putting her make up on at front desk. Valet staff friendly and helpful

Reviewed on Apr 29, 2026

West Baden Springs Hotel

8538 W Baden Ave West Baden Springs IN

2 hours drive from KFC Yum Center

Treat yourself to a luxury stay at West Baden Springs Hotel, where you can enjoy amenities like plush bedding, designer toiletries, and more. Deluxe amenities ...

The Brown Hotel

335 W Broadway Louisville KY

14 min walk from KFC Yum Center

The Brown Hotel is a Louisville luxury 4.5-star boutique property where you can pamper yourself with Egyptian cotton sheets, plush bedding, and more. The restaurant, ...

9.4/10 Exceptional! (1,183 reviews)

Food was just okay. It was during Derby week, so it was a fixed menu.

Reviewed on May 1, 2026

See all 1,156 properties in Southeastern Indiana

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.