
Central Iowa Luxury Vacations
Book a Luxury Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
Better together
Save up to ¥45,448 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place
Top Luxury Central Iowa Hotels

Des Lux Hotel
800 Locust St, Des Moines, IA
Treat yourself to a luxury stay at Des Lux Hotel, where you can enjoy amenities like designer toiletries, flat-screen TVs, and more. Notable amenities include ...
9.6/10 Exceptional! (1,016 reviews)
"Aaa"
Reviewed on Sep 17, 2025

Sonesta Essential Des Moines
4755 Merle Hay Road, Des Moines, IA
Indulge yourself with upscale accommodations at Sonesta Essential Des Moines, where you'll enjoy amenities like premium channels and more.
7.2/10 Good! (1,010 reviews)
"Staff is excellent"
Reviewed on Sep 17, 2025

La Quinta Inn & Suites by Wyndham Des Moines West Clive
1390 Nw 118th St, Clive, IA
Treat yourself to a luxury stay at La Quinta Inn & Suites by Wyndham Des Moines West Clive, where you can enjoy amenities like plush bedding, HDTVs, and ...
8.6/10 Excellent! (1,006 reviews)
LaQinta Clive, IA
"Our stay was excellent! Clean and well kept in good condition especially the poop annd spa Although I would change the outdoor furniture cushions. Moldy looking. The outside patio is very nice otherwise. We enjoyed our stay"
Reviewed on Sep 18, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.