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Top Luxury Northeast Ohio Hotels

InterContinental Cleveland by IHG

9801 Carnegie Ave Cleveland OH

4 min walk from Cleveland Clinic

Discover luxurious lodging at InterContinental Cleveland by IHG, where you can enjoy amenities like massage services, 24-hour room service, and more. Deluxe ...

8.8/10 Excellent! (844 reviews)

The bed was terribly uncomfortable. Perhaps a step stool next to the bed would help!

Reviewed on Nov 14, 2025

The Ritz-Carlton, Cleveland

1515 West Third Street Cleveland OH

10 min drive from Cleveland Clinic

Discover luxurious lodging at The Ritz-Carlton, Cleveland, where you can enjoy amenities like 24-hour room service, plush bedding, and more. The restaurant, ...

8.8/10 Excellent! (271 reviews)

Everything was great.

Reviewed on Oct 19, 2025

Drury Plaza Hotel Cleveland Downtown

1380 East 6th Street Cleveland OH

9 min drive from Cleveland Clinic

Visit Drury Plaza Hotel Cleveland Downtown for a relaxing stay in Cleveland. Popular amenities include an indoor pool, a restaurant, and a fitness center.

9.4/10 Exceptional! (2,629 reviews)

This was our first stay and it won't be a last. Friendly and helpful service, clean facilities and easy to get around. Also breakfast was great. A great stay in downtown Cleveland

Reviewed on Dec 2, 2025

See all 4,194 properties in Northeast Ohio

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.