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Top Luxury Central Missouri Hotels

Ramada by Wyndham Columbia

901 Conley Rd Columbia MO

24 min walk from University of Missouri

Ramada by Wyndham Columbia awaits for a deluxe vacation. Popular amenities include an outdoor pool and a fitness center.

7.4/10 Good! (1,001 reviews)

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Reviewed on Nov 30, 2025

voco The Tiger Hotel Columbia, MO by IHG

23 S 8th St Columbia MO

8 min walk from University of Missouri

Pamper yourself with a luxury stay at voco The Tiger Hotel Columbia, MO by IHG, where you can enjoy amenities like 24-hour room service, pillowtop beds, and ...

8.8/10 Excellent! (1,006 reviews)

This is the first time we have stayed at this facility and I was impressed! Location is excellent

Reviewed on Nov 24, 2025

Lodge Of Four Seasons Golf Resort, Marina & Spa

315 Four Seasons Dr. Lake Ozark MO

2 hours drive from University of Missouri

Pamper yourself with a luxe vacation at Lodge Of Four Seasons Golf Resort, Marina & Spa. Popular amenities include a spa, a golf course, and 5 bars.

7.2/10 Good! (1,076 reviews)

Nice clean room and staff was excellent. Some taller toilets or grab bars for us older people with knee problems would be a nice touch. This resort has been a staple in the community and is very well maintained. Would definitely stay here again.

Reviewed on Dec 5, 2025

See all 4,780 properties in Central Missouri

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.