Photo by Martin Tucker

Plan, book, travel with confidence
Better together
Save up to ￥109,000 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place

Top Luxury Northeast Mississippi Hotels

Super 8 by Wyndham Oxford

2201 Jackson Ave W Oxford MS

5 min drive from University of Mississippi

Treat yourself to some sumptuous lodging at Super 8 by Wyndham Oxford, where you'll find deep soaking bathtubs and premium bedding. The outdoor pool and hot ...

5.8/10 (1,011 reviews)

The main lobby was nice but when you got to the outside of the property it was in poor condition. The room they put us in wasn’t very clean. You would think for the area that it is in they would upgrade the building and make it look nice and update the rooms as well. Staff was nice and it was a quiet ...

Reviewed on May 11, 2026

Spark by Hilton Tupelo

186 Stone Creek Blvd Tupelo MS

2 hours drive from University of Mississippi

Indulge in a luxury vacation at Spark by Hilton Tupelo.

8.4/10 Very Good! (1,009 reviews)

Span call to room saying the computers went down and needed credit card information. Clerk did not know how they could have called rooms. there were at least two different rooms called. Did not give information and went downstairs.

Reviewed on May 11, 2026

Quality Inn Tupelo Central

1190 N Gloster St Tupelo MS

2 hours drive from University of Mississippi

Choose luxury at Quality Inn Tupelo Central, where you can enjoy amenities like plush bedding, premium channels, and more. Deluxe amenities at this hotel include ...

7.8/10 Good! (561 reviews)

The breakfast menu is amazing a few of the staff are amazing and parking well there could be more but I love the hidden park area in the back

Reviewed on May 11, 2026

See all 1,424 properties in Northeast Mississippi

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.