Southern Minnesota Romantic Vacations

Book a Romantic Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • payments icon

    Better together

    Save up to ¥45,448 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Plan, book, and manage your trip all in one place

Top Romantic Southern Minnesota Hotels

Alexander Mansion Bed and Breakfast

Alexander Mansion Bed and Breakfast

3.5 out of 5
274 East Broadway, Winona, MN
  • 2 hours drive from Mayo Clinic
Enjoy a stay at this romantic bed & breakfast, featuring a garden and a terrace for couples to enjoy.
10/10 Exceptional! (352 reviews)
"Hospitality and friendliness and the breakfast was simply AMAZING"

Reviewed on Sep 20, 2025

Alexander Mansion Bed and Breakfast
St James Hotel, a Historic Hotel of America

St James Hotel, a Historic Hotel of America

3.5 out of 5
406 Main St., Red Wing, MN
  • 2 hours drive from Mayo Clinic
If you and your special someone are ready for a getaway, you're sure to love the spa and garden at this historic hotel. You'll also appreciate the luxury bedding, ...
9.2/10 Wonderful! (1,010 reviews)

Couples like: full-service spa, bar

Fam reunion
"Had one “snotty” waitress the night we left just trying to enjoy the outdoor venue. Too bad since most of the stay was pretty good."

Reviewed on Sep 24, 2025

St James Hotel, a Historic Hotel of America
AmericInn by Wyndham Austin

AmericInn by Wyndham Austin

2.5 out of 5
1700 8th St NW, Austin, MN
  • 2 hours drive from Mayo Clinic
Enjoy a stay at this romantic hotel, featuring a hot tub and a lobby fireplace for couples to enjoy.
8.6/10 Excellent! (695 reviews)
"This property was clean and quiet. The staff were friendly and amazing. If I could give above a 10 I would"

Reviewed on Sep 18, 2025

AmericInn by Wyndham Austin
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.