Upstate South Carolina Romantic Vacations

Book a Romantic Hotel + Flight or Car together to unlock savings

Photo by Victoria S
  • Plan, book, travel with confidence

  • Better together

    Save up to ¥45,448 when you book a flight and hotel together*

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

    Rest easy

    Plan, book, and manage your trip all in one place

Top Romantic Upstate South Carolina Hotels

Relax on the shore of Lake Hartwell in our Fair Play retreat

Relax on the shore of Lake Hartwell in our Fair Play retreat

Fair Play
  • 34 min drive from Clemson University
Book a stay at this business-friendly vacation home in Fair Play. Enjoy free WiFi, a water park, and a garden. Popular attractions Lake Hartwell and Glenn Ferry ...
9.8/10 Exceptional! (197 reviews)

Couples like: spa tub, fireplace

Travelers say...
We have stayed here several times and enjoy the location, space and amenities. It has been consistently pleasant and comfortable. Everything is very clean and well organized. It's a perfect getaway.

Reviewed on Oct 20, 2025

Relax on the shore of Lake Hartwell in our Fair Play retreat
Fall fun at the cabin! Convenient to Lake Keowee and Clemson

Fall fun at the cabin! Convenient to Lake Keowee and Clemson

Seneca
  • 22 min drive from Clemson University
Enjoy a stay at this romantic cabin, featuring a garden and in-room fireplaces for couples to enjoy.
9/10 Wonderful! (74 reviews)
It was a lovely place to stay!

Reviewed on Jul 29, 2025

Fall fun at the cabin! Convenient to Lake Keowee and Clemson
Peaceful Oasis Convenient to Greenville!

Peaceful Oasis Convenient to Greenville!

Simpsonville
  • 2 hours drive from Clemson University
Stay at this vacation home in Simpsonville. Enjoy a water park, a garden, and laundry facilities. Popular attractions Haywood Mall and Gravitopia Trampoline ...
9.8/10 Exceptional! (112 reviews)
Work trip in Greer
This property worked out perfect for myself and one other individual. We had a full week of work booked at a cuatomer that was 19 minutes away from this property and it worked out perfect for us.

Reviewed on Aug 4, 2025

Peaceful Oasis Convenient to Greenville!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.