Upstate South Carolina Romantic Vacations 2026

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Top Romantic Upstate South Carolina Hotels

Fall fun at the cabin! Convenient to Lake Keowee and Clemson

Seneca SC

22 min drive from Clemson University

Enjoy a stay at this romantic cabin, featuring a garden and in-room fireplaces for couples to enjoy.

Peaceful Oasis Convenient to Greenville!

Simpsonville SC

2 hours drive from Clemson University

Stay at this vacation home in Simpsonville. Enjoy a water park, a garden, and laundry facilities. Popular attractions LeMans Karting and Frankie's Fun Park are ...

10/10 Exceptional! (115 reviews)

"Pet friendly"

Reviewed on May 24, 2026

Greenville Marriott

One Parkway E Greenville SC

2 hours drive from Clemson University

Rekindle the romance with your special someone. Consider booking a getaway at this hotel where you're sure to love the premium mattresses and luxury bedding. ...

See all 3,080 properties in Upstate South Carolina

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.