Eastern South Dakota Pet-friendly Vacations

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Top Pet-friendly Eastern South Dakota Hotels

La Quinta Inn & Suites by Wyndham Sioux Falls

La Quinta Inn & Suites by Wyndham Sioux Falls

3 out of 5
4521 W. 41st Street Sioux Falls SD
  • 9 min drive from Denny Sanford Premier Center
Dogs and cats may join you (for a fee) during your stay at this pet-friendly hotel. Take the opportunity to stretch your legs on the nearby hiking or biking ...
9.2/10 Wonderful! (1,558 reviews)
Everything was great

Reviewed on Feb 18, 2026

La Quinta Inn & Suites by Wyndham Sioux Falls
Econo Lodge Sioux Falls Empire Mall

Econo Lodge Sioux Falls Empire Mall

2 out of 5
3500 Gateway Boulevard Sioux Falls SD
  • 9 min drive from Denny Sanford Premier Center
This pet-friendly hotel welcomes dogs and cats (fees apply).
7/10 Good! (442 reviews)
Economy hotel, no thrills, but it's nice
Staff was really nice. Rooms are spacious. Good value and convenient to many stores/restaurants, etc. Rooms for clean.

Reviewed on Oct 18, 2022

Econo Lodge Sioux Falls Empire Mall
Kelly Inn & Suites Mitchell South Dakota

Kelly Inn & Suites Mitchell South Dakota

2.5 out of 5
1010 Cabela Drive Mitchell SD
  • 3 hours drive from Denny Sanford Premier Center
This pet-friendly hotel welcomes dogs for free.
8/10 Very Good! (1,092 reviews)
While the hotel looks like a nice place there were so many things which required maintenance. The room key entry didn’t work. The back door key entry didn’t work. Jets in hot tub didn’t work and shower diverter in our room didn’t work. Breakfast was fine. Glad we got the reduced price from ...

Reviewed on Feb 13, 2026

Kelly Inn & Suites Mitchell South Dakota
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.