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Top Pet-friendly South Carolina Midlands Hotels

La Quinta Inn & Suites by Wyndham Florence

2123 W Lucas St Florence SC

3 hours drive from Fort Jackson

This pet-friendly hotel welcomes dogs and cats (fees apply).

7.8/10 Good! (1,600 reviews)

I was very satisfied with the staying there.

Reviewed on May 10, 2026

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

7333 Garners Ferry Rd Columbia SC

9 min drive from Fort Jackson

This pet-friendly hotel welcomes dogs and cats (fees apply).

8/10 Very Good! (1,016 reviews)

The hotel is freshly renovated, feels very modern and the room even had a clothes steamer (which my daughter needed for a dress). Breakfast was well stocked and the staff friendly and helpful.

Reviewed on May 10, 2026

Hampton Inn Columbia I-26/Harbison Blvd.

101 Woodcross Dr Columbia SC

31 min drive from Fort Jackson

Hiking and biking trails are ready for you to explore near this lakefront hotel, where dogs and cats can stay for an additional fee.

9.2/10 Wonderful! (1,007 reviews)

What a nice place to stay! Just 20 minutes to the U of SC campus. Staff was very friendly and accommodating during our few day stay. The room was very clean, updated, and a decent size. They offer a continental breakfast with coffee, yogurts, oatmeal with toppings and a few hot items that change ...

Reviewed on May 10, 2026

See all 3,277 properties in South Carolina Midlands

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.