South Carolina Midlands Pet-friendly Vacations
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Top Pet-friendly South Carolina Midlands Hotels
La Quinta Inn & Suites by Wyndham Florence
2123 W Lucas St, Florence, SC
This pet-friendly hotel welcomes dogs and cats (fees apply).
7.8/10 Good! (1,680 reviews)
"Clean, easy check in, convenient"
Reviewed on Sep 14, 2025
La Quinta Inn by Wyndham Columbia SE / Fort Jackson
7333 Garners Ferry Rd, Columbia, SC
This pet-friendly hotel welcomes dogs and cats (fees apply).
7.4/10 Good! (1,023 reviews)
"The layout of the hotel and the parking lot did not make sense. Parking was at the very end of the hotel and the main entrance was at the front. There was a door at the end for parking lot entrance and there was a single elevator at that point that was in less than decent condition. Since there was ..."
Reviewed on Sep 26, 2025
Hampton Inn Columbia I-26/Harbison Blvd.
101 Woodcross Dr, Columbia, SC
Hiking and biking trails are ready for you to explore near this lakefront hotel, where dogs and cats can stay for an additional fee.
9/10 Wonderful! (1,008 reviews)
"clean room. friendly staff. good breakfast."
Reviewed on Sep 26, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
