Southwest Coast Florida Pet-friendly Vacations

Book a Pet-friendly Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to ¥45,448 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Top Pet-friendly Southwest Coast Florida Hotels

La Quinta Inn & Suites by Wyndham Bonita Springs Naples N.

La Quinta Inn & Suites by Wyndham Bonita Springs Naples N.

3 out of 5
28600 Trails Edge Blvd Bonita Springs FL
  • 24 min drive from Key West Express
Make it a pet-friendly trip and bring along your four-legged friend. Dogs and cats are welcome (fees apply) at this city-center hotel.
9/10 Wonderful! (1,308 reviews)
Spacious suite and great service.

Reviewed on Feb 17, 2026

La Quinta Inn & Suites by Wyndham Bonita Springs Naples N.
La Quinta Inn & Suites by Wyndham Sarasota Downtown

La Quinta Inn & Suites by Wyndham Sarasota Downtown

3 out of 5
Sarasota FL
  • 2 hours drive from Key West Express
Make it a pet-friendly trip and bring along your four-legged friend. Dogs are welcome (fees apply) at this city-center hotel.
6.2/10 (1,005 reviews)
It was a horrible experience, the furniture had stains. The bed mattress had collapses where people have been laying it for numerous times. It only took about five minutes. We were back downstairs checking out. Would love to send you photos.

Reviewed on Feb 16, 2026

La Quinta Inn & Suites by Wyndham Sarasota Downtown
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

3 out of 5
20091 Summerlin Road Fort Myers FL
  • 6 min drive from Key West Express
Hiking and biking trails are ready for you to explore near this oceanfront hotel, where dogs can stay for an additional fee.
8.2/10 Very Good! (1,021 reviews)
The room smelled like a dirty fish tank. We asked to move rooms and there wasn’t one available. On Saturday night there was no hot water for showers. We did complain and nothing changed. On Sunday night we were informed that there would be no water from 8-5 on Monday. We had to set an alarm to get ...

Reviewed on Feb 18, 2026

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.