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Top Luxury Eastern Iowa Hotels

Hotel Julien Dubuque

200 Main Street Dubuque IA

2 hours drive from University of Iowa

Go for a luxurious stay at Hotel Julien Dubuque, where you can enjoy amenities like pillowtop beds, designer toiletries, and more. Deluxe amenities at this hotel ...

9/10 Wonderful! (1,719 reviews)

Room was very Nice! Pool and Hot tub excellent! Loaction was perfect! Had view of Mississippi River. Loved the stay!

Reviewed on Jan 23, 2026

La Quinta Inn by Wyndham Davenport & Conference Center

3330 E Kimberly Rd Davenport IA

2 hours drive from University of Iowa

Stay in the lap of luxury at La Quinta Inn by Wyndham Davenport & Conference Center, where you can enjoy amenities like premium channels, flat-screen TVs, and ...

7.2/10 Good! (1,002 reviews)

Everything was excellent

Reviewed on Jan 19, 2026

Travelodge by Wyndham Iowa City

2216 N Dodge St Iowa City IA

6 min drive from University of Iowa

Treat yourself to upscale accommodations with a stay at Travelodge by Wyndham Iowa City, where you'll enjoy amenities like premium channels and more.

8/10 Very Good! (1,002 reviews)

Comfortable, large quiet room. Helpful staff.

Reviewed on Jan 17, 2026

See all 1,553 properties in Eastern Iowa

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.