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Top Luxury Northern Kentucky Hotels

21c Museum Hotel Louisville

700 W Main Street Louisville KY

3 hours drive from Ark Encounter

21c Museum Hotel Louisville is one of the Louisville luxury 4.5-star boutique properties where you can treat yourself to Champagne service, massage services, ...

9.2/10 Wonderful! (1,001 reviews)

Staff very helpful. Rooms are spacious and clean. Lobby exhibits unique and interesting. Hotel well situated in downtown to access popular tourist attractions. Enjoyed our stay.

Reviewed on Jan 20, 2026

21c Museum Hotel Cincinnati

609 Walnut St Cincinnati OH

1 hour drive from Ark Encounter

21c Museum Hotel Cincinnati is one of the Cincinnati luxury 4.5-star boutique properties where you can treat yourself to Champagne service, Egyptian cotton sheets, ...

8.6/10 Excellent! (1,007 reviews)

From check in throughout our stay was wonderful. The staff at 21c is fabulous. The atmosphere is welcoming.

Reviewed on Jan 24, 2026

The Cincinnatian Hotel Curio Collection by Hilton

601 Vine Street Cincinnati OH

1 hour drive from Ark Encounter

Be treated to luxurious accommodations at The Cincinnatian Hotel Curio Collection by Hilton, where you can enjoy amenities like plush bedding, designer toiletries, ...

7.6/10 Good! (1,004 reviews)

The staff was amazing and Patrick, the valet manager, was really nice and professional. We loved the room we stayed in and the hotel had such a great 1920s vibe! We will definitely be coming back for anniversaries!!

Reviewed on Jan 20, 2026

See all 6,159 properties in Northern Kentucky

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.