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Top Luxury Eastern Piedmont Hotels

The Umstead Hotel and Spa

100 Woodland Pond Dr Cary NC

29 min drive from Duke University

Pamper yourself with an extravagant stay at The Umstead Hotel and Spa, where you'll find deep soaking bathtubs and pillowtop beds. The spa, outdoor pool, and ...

9.4/10 Exceptional! (722 reviews)

Great property: However, both the restaurant and guest attire was not congruent with a what a 5- start restaurant should be. Portions were nonexistent and after spending $360 for dinner I left the table starving; not to mention, allowing jeans and t-shirts for "fine dining" is embarrassing. Needless ...

Reviewed on Jan 11, 2026

The Carolina Inn, a Destination by Hyatt Hotel

211 Pittsboro Street Chapel Hill NC

16 min drive from Duke University

Go for a luxurious stay at The Carolina Inn, a Destination by Hyatt Hotel, where you can enjoy amenities like pillowtop beds, premium channels, and more. Notable ...

9.4/10 Exceptional! (1,002 reviews)

Awesomr

Reviewed on Jan 13, 2026

The Mayton

301 S Academy St Cary NC

37 min drive from Duke University

The Mayton is one of the Cary luxury 4-star boutique properties where you can pamper yourself with Champagne service, pillowtop beds, and more. Notable amenities ...

9.4/10 Exceptional! (728 reviews)

Great vibe — elegant and cozy (but not stuffy). The hotel location drew us and did not disappoint. The Downtown Cary Park is easily accessible! Also walked to restaurants a few blocks away.

Reviewed on Jan 8, 2026

See all 4,746 properties in Eastern Piedmont

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.