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Top Cheap Panhandle Plains Hotels

Studio 6 Amarillo, TX – West Medical Center

6801 W Interstate 40, Amarillo, TX

4 hours drive from Texas Tech University

Book a stay at this business-friendly hotel in Amarillo. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the breakfast and the pool ...

7.4/10 Good! (1,012 reviews)

"This was only an overnight stay. But, it was way better than I expected, especially with the low cost. Room was clean, roomy and very comfortable. Staff was very friendly. Will definitely be my go to stop to and from Colorado."

Reviewed on Sep 24, 2025

Days Inn by Wyndham Amarillo East

1701 I-40E, I-40 Exit 71 Ross-Osage, Amarillo, TX

4 hours drive from Texas Tech University

Book a stay at this business-friendly hotel in Amarillo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

6.6/10 (1,018 reviews)

"Clean rooms. Quick check in. Was just a quick stop."

Reviewed on Sep 27, 2025

Extend-a-Suites - Extended Stay, I-40 Amarillo West

3411 I-40 W, Amarillo, TX

4 hours drive from Texas Tech University

Stay at this hotel in Amarillo. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions The Galleries at Sunset Center and Amarillo Little ...

4.8/10 (1,001 reviews)

Two thumbs up

"Great staff and clean rooms."

Reviewed on Aug 22, 2025

See all 2,136 properties in Panhandle Plains

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.