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Top Cheap Panhandle Plains Hotels

Studio 6 Amarillo, TX – West Medical Center

6801 W Interstate 40, Amarillo, TX

4 hours drive from Texas Tech University

Book a stay at this business-friendly hotel in Amarillo. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the breakfast and the pool ...

7.4/10 Good! (1,001 reviews)

"Just an overnight stay during a longer road-trip. For 56$ a great value for a place to crash for the night. Free hot breakfast which was nice."

Reviewed on Sep 4, 2025

Days Inn by Wyndham Amarillo East

1701 I-40E, I-40 Exit 71 Ross-Osage, Amarillo, TX

4 hours drive from Texas Tech University

Book a stay at this business-friendly hotel in Amarillo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

6.6/10 (1,006 reviews)

You het what you pay for

"Staff consisted of one desk clerk but he was very polite and attentive. The room was clean but old. I put the blame of hotel conditions on the owner. Its what you would expect for the price"

Reviewed on Sep 9, 2025

Extend-a-Suites - Extended Stay, I-40 Amarillo West

3411 I-40 W, Amarillo, TX

4 hours drive from Texas Tech University

Stay at this hotel in Amarillo. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions The Galleries at Sunset Center and Amarillo Little ...

4.8/10 (1,004 reviews)

Two thumbs up

"Great staff and clean rooms."

Reviewed on Aug 22, 2025

See all 2,091 properties in Panhandle Plains

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.