Photo by Andrew Hershfeld

Plan, book, travel with confidence
Better together
Save up to ￥45,448 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place

Top Beach Northeast Missouri Hotels

Best Western St. Louis-Kirkwood Route 66

1200 S Kirkwood Road Kirkwood MO

24 min drive from St. Louis Union Station

Book a stay at this business-friendly hotel in Kirkwood. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

8.2/10 Very Good! (1,372 reviews)

The location is wonderful. Ten minutes from Barnes Hospital, and Walmart and numerous restaurants within 2 minutes.

Reviewed on Nov 30, 2025

See all 2,765 properties in Northeast Missouri

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.