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Top Adventure Southeast Minnesota Hotels

Kahler Grand Hotel

20 2nd Ave Sw Rochester MN

2 min walk from Mayo Clinic

Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and ...

8.4/10 Very Good! (1,945 reviews)

Love staying here during appointments at Mayo Clinic. Our home away from home, warm, welcoming and cozy. Best access to the clinic during the winter months is through the subway system. Both restaurants on site are excellent. Highly recommend the valet service.

Reviewed on Mar 7, 2026

Country Inn & Suites by Radisson, Rochester, MN

4323 Highway 52 North, West Frontage Rd Rochester MN

10 min drive from Mayo Clinic

Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...

7.4/10 Good! (1,002 reviews)

Swim pool and jacuzzi, no water in them. Lamp next to bed didn’t work, had to change plug to new outlet. Hair in sink, wash cloths had stains.

Reviewed on Mar 5, 2026

Hotel Indigo Rochester – Mayo Clinic Area by IHG

220 S Broadway Rochester MN

6 min walk from Mayo Clinic

Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, a rooftop terrace, and breakfast (surcharge). Our guests praise the restaurant and ...

8.8/10 Excellent! (952 reviews)

Overall it was an ok stay. Very small room. Bathroom didn’t have a working vent. Common area microwave barely functioned.

Reviewed on Mar 5, 2026

See all 939 properties in Southeast Minnesota

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.