A large white building with a dome and a statue in front, surrounded by fountains and trees.

Find Resorts & Hotels with Spas in St. Louis, MO

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on St. Louis Resorts & Hotels with Spas

Tonight
Oct 23 - Oct 24
Tomorrow
Oct 24 - Oct 25
This weekend
Oct 23 - Oct 25
Next weekend
Oct 30 - Nov 1

Our top choices for St. Louis hotels with a spa

A couple relaxing by a window overlooking a bridge and water.
A modern hotel lobby with a glass facade, seating area, and a staircase.
A modern dining area with a long table set for a meal, large windows offering a view of a bridge, and a stone accent wall.
A bar area with a bartender, a bar counter with various bottles, and a view of the Gateway Arch.

1. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
Downtown St. Louis
  • Discover a tranquil haven with 12 treatment rooms, outdoor pool, and breathtaking views at this rejuvenating spa retreat.
￥58,774
￥68,723 total
includes taxes & fees
Oct 25 - Oct 26
Four Seasons Hotel St Louis
A reception desk with a wooden finish and the name "IDOL WOLF" on it.
A modern bathroom with a bathtub, a vanity with a mirror, and a shower area.
A hotel room with two beds, a large padded headboard, a flat-screen TV, a window with a city view, and a small side table with a plant.
A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.

2. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
  • Discover spa services, a steam room, and an Olympic-sized indoor pool at this modern hotel, all designed for rejuvenating getaways.
￥22,514
￥27,110 total
includes taxes & fees
Nov 15 - Nov 16
21C Museum Hotel St Louis
A two-story building with a dark entrance, large windows, and a brick facade.
A room with a green armchair, a round table, a lamp, and a mirror on the wall.
A bar area with a neon sign, a lamp, and various food and drink items.
A bathroom with a white sink, dark wooden door, and a shower area with striped glass walls.

3. Truitt Hotel

Truitt Hotel
Lafayette Square
￥26,331
￥31,963 total
includes taxes & fees
Oct 27 - Oct 28
Truitt Hotel
A modern spa with a curved reception desk, a large mirror, and a decorative water feature.
A bakery display case with various pastries and cakes.
A bar area with multiple seating arrangements, a stage, and a chandelier.
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.

4. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
  • Riverside wellness oasis offers full-service spa with aromatherapy and hydrotherapy for a restorative retreat.
￥20,959
￥27,093 total
includes taxes & fees
Nov 23 - Nov 24
Ameristar Casino Resort and Spa
A modern kitchen with wooden cabinets, a central island, and framed artwork on the walls.
An outdoor seating area with modern furniture, a bar, and large windows offering views of a cityscape.
A bar area with leather seating, a bar counter, and shelves of bottles.
An indoor dining area with a long table, chairs, hanging plants, and a view of a brick building through large windows.

5. The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
Clayton
  • Revel in a rejuvenating spa retreat with aromatherapy treatments and hot stone massages at this luxury St. Louis hotel.
￥90,747
￥105,936 total
includes taxes & fees
Nov 1 - Nov 2
The Ritz-Carlton, St. Louis
View all properties

Choose what matters most at spa hotels in St. Louis

Pool
Hot tub
Breakfast included
Gym
5 stars

Top St. Louis Hotel Reviews

The Westin St. Louis

The Westin St. Louis

10/10 Excellent
"Great location! Clean room."
Liverio 2-night trip
Posted 9 hours ago
The Westin St. Louis
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

10/10 Excellent
"We enjoyed the fresh popcorn and it was within walking distance from the train station."
Tamela 1-night trip
Posted 13 hours ago
Pear Tree Inn St. Louis Near Union Station
Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent
"Great location, friendly staff. Well maintained and clean."
Matt 1-night trip
Posted 14 hours ago
Drury Plaza Hotel St. Louis Union Station

Frequently asked questions

Looking to vacation at a spa hotel in St. Louis?
Soothe the senses with some time in one of our wonderful spa hotels. Travelers love the fascinating museums and live music scene in St. Louis so get ready for a cultural tour. Hotels with spas are the perfect way to take a break from your daily routine and add a layer of luxury to your holiday.
What is the best spa hotel in St. Louis?
Ameristar Casino Resort and Spa is a top luxury spa hotel featuring 6 restaurants, a casino, a 24-hour fitness center, and an outdoor pool. Treat yourself to a facial, body scrub, or hydrotherapy at Ara. Another popular spa hotel in St. Louis is Four Seasons Hotel St Louis.
How many spa hotels will I find in St. Louis?
Among Expedia's 1964 accommodation options in St. Louis, there are 2 spa hotels.
What's there to see and do in St. Louis?
Experience St. Louis and visit St. Louis Union Station, St. Louis Zoo, and St. Louis Aquarium at Union Station. If you have spare time during your trip, you might want to make a stop at The St. Louis Wheel and Energizer Park.
What is a St. Louis spa hotel?
Spa hotels in St. Louis provide lodging and have an on-site spa offering services like couples massages and beauty treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.

Explore a world of travel with Expedia