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Our top choices for Southern Louisiana hotels

A spacious lobby with a high ceiling, a reception desk, seating areas, and a staircase to an upper level.

1. Wingate by Wyndham Lafayette Airport

Lafayette

marvin

￥13,763 total

includes taxes & fees

Nov 8 - Nov 9

A spacious lobby with a reception desk, seating area, and a large cityscape mural.

2. La Quinta Inn & Suites by Wyndham Lafayette Oil Center

Lafayette

Katie

￥15,306 total

includes taxes & fees

Nov 3 - Nov 4

A hotel lobby with a reception desk, seating area, and a large framed picture on the wall.

3. Comfort Inn & Suites Scott-West Lafayette

Scott

Sandra

￥17,468 total

includes taxes & fees

Nov 28 - Nov 29

A hotel entrance with a covered driveway, palm trees, and a sign for Homewood Suites.

4. Homewood Suites by Hilton Lafayette, LA

Lafayette

Latausha

￥16,938 total

includes taxes & fees

Nov 20 - Nov 21

A bar area with a long counter, multiple bar stools, shelves with bottles, and a TV mounted above the bar.

5. DoubleTree by Hilton Hotel Lafayette

Lafayette

Allan Michael

￥16,015 total

includes taxes & fees

Nov 27 - Nov 28

A modern lobby with grey upholstered armchairs, a round wooden ottoman, and a patterned rug.

6. Drury Inn & Suites Lafayette, LA

Lafayette

Tina

￥21,751 total

includes taxes & fees

Nov 5 - Nov 6

A hotel reception area with a counter, a refrigerator stocked with beverages, and a snack bar with various food items.

7. Holiday Inn Express Hotel & Suites Scott - Lafayette West by IHG

Scott

Adriano

￥20,375 total

includes taxes & fees

Nov 29 - Nov 30

A modern lobby with a central bar area, seating arrangements, and a reception desk.

8. SpringHill Suites by Marriott Lafayette South at River Ranch

River Ranch

Lori

￥24,786 total

includes taxes & fees

Nov 29 - Nov 30

A building with a stone facade, a covered entrance with a wooden arch, and a seating area with chairs.

9. Staybridge Suites Lafayette by IHG

Lafayette

Thierry

￥19,024 total

includes taxes & fees

Nov 22 - Nov 23

An indoor swimming pool with clear water, surrounded by lounge chairs and a brick wall.

10. Holiday Inn & Suites Lafayette North by IHG

Lafayette

Melinda

￥17,212 total

includes taxes & fees

Nov 29 - Nov 30

A modern outdoor seating area with fire pit, chairs, and a covered patio.

11. Home2 Suites By Hilton Lafayette I-10

Lafayette

Kristina

￥20,791 total

includes taxes & fees

Nov 8 - Nov 9

A breakfast bar with various food items and a beverage station.

12. Hampton Inn Broussard-Lafayette Area

Broussard

Julie

￥15,624 total

includes taxes & fees

Nov 27 - Nov 28

A modern lobby with a reception desk, seating area, and a large plant.

13. Comfort Suites Oil Center

Lafayette

Cedric

￥14,649 total

includes taxes & fees

Nov 29 - Nov 30

A modern dining area with multiple tables and chairs, a central bar area, and artwork on the walls.

14. Sonesta ES Suites Lafayette Airport Extended Stay

Lafayette

dawn

￥13,698 total

includes taxes & fees

Nov 8 - Nov 9

An outdoor seating area with wicker furniture, a fire pit, and ambient lighting.

15. Home2 Suites by Hilton Parc Lafayette

Lafayette

Doris

￥24,591 total

includes taxes & fees

Nov 22 - Nov 23

A Holiday Inn Express & Suites building with a brick facade and a flat roof.

16. Holiday Inn Express Hotel & Suites Lafayette South by IHG

Lafayette

Jennifer

￥15,944 total

includes taxes & fees

Nov 3 - Nov 4

17. stayAPT Suites Lafayette South

Lafayette

Jalea

￥17,938 total

includes taxes & fees

Nov 1 - Nov 2

A modern dining area with multiple tables and chairs, a kitchen in the background, and a wall with motivational quotes.

18. Fairfield Inn & Suites by Marriott Lafayette South

Lafayette

Dawn

￥16,145 total

includes taxes & fees

Nov 8 - Nov 9

A spacious lobby with a modern design, featuring a seating area, a fireplace, and a refreshment bar.

19. Hilton Garden Inn Lafayette/Cajundome

Lafayette

Shelby

￥17,533 total

includes taxes & fees

Nov 22 - Nov 23

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Vacation Rentals in Southern Louisiana

Vacation Home

A modern living room with a sofa, armchair, coffee table, and a dining area with a table and chairs.

Enclave 1 Bedroom Suites

Lafayette

"We had a great stay here! Nice location and had everything we needed for a long weekend."

Vacation Home

A modern kitchen with grey cabinets, a central island with a sink, and a dining area with wicker chairs.

Enclave 3 Bedroom Luxury Homes

Lafayette

"Great Value! I highly recommend this property over hotels in the area."

Vacation Home

A hotel room with a bed, a desk, a chair, a clock, and a window with curtains.

Downtown Lafayette 4BR Home With Parking

Downtown Lafayette

"It is a beautiful home the house was"

Cottage

A beach with the sun setting over the ocean, creating a serene atmosphere.

Blue Dolphin Inn and Cottages

Grand Isle

"When we got there, it was so clean and it felt so spacious , 10/10 could go there again and get the same room 😊"

Cottage

A bedroom with a bed, a television on a stand, a wardrobe, and a door leading to another room.

Walk to 1st Street: Family Home in Thibodaux!

Thibodaux

"This little home reminded me of my grandma's home when I was young. It has lots of old fashioned charm with modern decor. We were here for a birthday party so we didn't have an opportunity to enjoy downtown, but we did enjoy our stay. Next time we will bring our pup. He will love the nice backyard."

Cottage

A spacious living area with a stone fireplace, a grey sofa, and a kitchen with white cabinets and a large island.

Spacious Lake Charles Craftsman - Pet Friendly!

Lake Charles

"This is a very beautiful home. I loved the openness of the rooms. I would definitely recommend this place for anyone looking for a place to stay with their family. I would definitely stay there again. "

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Stay near popular Southern Louisiana attractions

A large tree with extensive branches and moss-covered trunks in a park.

University of Louisiana at Lafayette

8.6/10 (816 reviews)

Take a campus tour or just explore the area of University of Louisiana at Lafayette, during your trip to Lafayette. You can attend a sporting event while in the area.

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Learn more about Southern Louisiana

Explore the family-friendly area of Southern Louisiana—casinos, sports teams, and sights from Youngsville Sports Complex to Lake Peigneur.

See all hotels in Southern Louisiana

A sunset over a calm lake with a tree silhouette and a cloudy sky.

Top Southern Louisiana Hotel Reviews

The Mulberry Hotel

10/10 Excellent

"Wonderdul stay"

Plantation Inn of Houma

8/10 Good

"This motel is centrally located in Houma with plenty of dining options nearby. The property is clean and maintained. The lobby is clean with a nice staff member to greet you. Check in was smooth and quick. The room was very clean and comfortable. I always sleep well when I visit at this location. I have zero complaints about it."