A modern glass building with a curved facade and a sign reading "The Kentucky Center".

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Check availability on Southern Indiana Resorts & Hotels with Spas

Tonight
Oct 1 - Oct 2
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Oct 2 - Oct 3
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Oct 2 - Oct 4
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Oct 9 - Oct 11

Our top choices for Southern Indiana hotels with a spa

A modern interior with large windows offering a city view, a circular light fixture, and leather seating.
An outdoor patio with black tables and chairs, surrounded by large windows and a row of arches.
A modern hotel room with a large window, a sofa, a red armchair, and a small table.
A nighttime view of The GALT and The Galthouse buildings with illuminated signage, a busy street with light trails from moving vehicles, and a modern urban setting.

1. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
Downtown Louisville
  • Riverside sanctuary offers rejuvenating spa treatments, panoramic fitness views, and river-facing balconies for a relaxing urban retreat.
￥23,677
￥27,858 total
includes taxes & fees
Oct 30 - Oct 31
Galt House Hotel Trademark Collection by Wyndham
A restaurant with round tables, chairs, chandeliers, and a bar area.
A hot tub with a pool, indoor seating area, and a view of the pool.
A casino with multiple gaming tables and slot machines, a red carpet, and ornate chandeliers.
A large hotel with a prominent 'Caesars' sign, multiple floors, and a symmetrical facade.

2. Caesars Southern Indiana Hotel & Casino - A Caesars Rewards Destination

Caesars Southern Indiana Hotel & Casino - A Caesars Rewards Destination
Elizabeth
  • Refresh your spirit at this riverfront hotel with daily spa treatments and couples rooms, where aromatherapy and Ayurvedic therapies await.
￥9,528
￥13,725 total
includes taxes & fees
Nov 1 - Nov 2
Caesars Southern Indiana Hotel & Casino - A Caesars Rewards Destination
A treatment room with a massage table, a desk with a computer, and a large mirror.
A luxurious bathroom with a large mirror, a bathtub, and a shower area.
A poolside area with lounge chairs and a towel with a monogram.
A large, multi-story hotel with a prominent dome and arched windows, featuring a well-lit entrance and landscaped gardens.

3. Belterra Casino Resort

Belterra Casino Resort
Florence
  • Experience soothing river views and rejuvenating spa treatments at this hotel with indoor and outdoor pools.
￥19,954
￥24,286 total
includes taxes & fees
Oct 15 - Oct 16
Belterra Casino Resort
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.
A rooftop bar with outdoor seating, including sofas and chairs, and a bar area with a television screen.
A modern interior with a fireplace, bookshelves, and seating areas.
A lobby with a marble floor, a reception desk, and a large chandelier.

4. Omni Louisville Hotel

Omni Louisville Hotel
Downtown Louisville
  • Immerse in spa bliss at this Louisville hotel where Mokara Spa offers therapeutic treatments and rooftop relaxation awaits.
￥39,987
￥47,049 total
includes taxes & fees
Oct 30 - Oct 31
Omni Louisville Hotel
A cozy room with a geometric-patterned ceiling, a sofa, and a chair.
A steam fountain in a brick alleyway.
A cozy room with wooden walls, a table with a lamp, and shelves displaying books and decorative items.
A restaurant with multiple dining tables, a long bench seating area, and framed artwork on the walls.

5. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
Downtown Louisville
  • Experience a rejuvenating spa escape at this luxury boutique hotel with massage rooms and 24-hour fitness center in downtown Louisville.
￥26,628
￥32,118 total
includes taxes & fees
Oct 25 - Oct 26
21c Museum Hotel Louisville
A hotel lobby with a chandelier, wooden railings, a reception desk, and a large arched doorway.
A conference room with multiple tables and chairs, a flat-screen TV mounted on the wall, and a large window with blinds.
An indoor swimming pool with clear water, surrounded by lounge chairs and a small seating area.
A spacious indoor area with a staircase, a vending machine, and a business center sign.

6. Quality Inn Seymour I-65

Quality Inn Seymour I-65
Seymour
  • Revitalize your body and spirit in this tranquil hotel featuring a full-service daily spa, indoor pool, and 24-hour fitness center.
￥12,711
￥14,237 total
includes taxes & fees
Nov 1 - Nov 2
Quality Inn Seymour I-65
A rustic bar area with a wooden bar counter, stools, and a variety of bottles and glasses.
A living room with a sofa, coffee table, and a television mounted on the wall.
A cozy room with a wooden wall, a sofa, and a dining table.
A porch with white rocking chairs and a table, a window with blinds, and a view of a green landscape.

7. Pillow and Paddock B&B

Pillow and Paddock B&B
La Grange
  • Relax in a cozy bed and breakfast retreat with a steamy hot tub, rejuvenating spa services, and a peaceful garden sanctuary.
￥51,657
￥56,948 total
includes taxes & fees
Oct 18 - Oct 19
Pillow and Paddock B&B
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Choose what matters most at spa hotels in Southern Indiana

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Southern Indiana Hotel Reviews

Hampton Inn New Albany Louisville West

Hampton Inn New Albany Louisville West

10/10 Excellent
"Good vibes"
Daniel 2-night trip
Posted less than an hour ago
Hampton Inn New Albany Louisville West
Drury Inn & Suites Evansville East

Drury Inn & Suites Evansville East

10/10 Excellent
"The manager was amazing and obviously really cares about his hotel. I saw him helping people find seats for kickback, working the front desk, helping with breakfast, and by the elevators talking with guests. He was pleasant and helpful at all times."
Deirdre 1-night trip
Posted 2 days ago
Drury Inn & Suites Evansville East

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