A modern glass building with a curved facade and a sign reading "The Kentucky Center".

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Check availability on Southern Indiana Luxury Hotels

This weekend
Oct 30 - Nov 1
Next weekend
Nov 6 - Nov 8

Our top choices for Southern Indiana luxury hotels

A grand lobby with ornate columns, plush seating, and a chandelier.

1. The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,433 reviews)
  • cleanliness
    Elegantly designed spaces and refined comforts define this historic Louisville hotel offering a boutique feel in the city center.
The price is ￥18,699
￥22,001 total
includes taxes & fees
Nov 25 - Nov 26
The Brown Hotel
A classical gold statue in front of a multi-story building with large windows and a brick facade.

2. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville
9.4 out of 10, Exceptional, (1,007 reviews)
  • cleanliness
    Museum-infused luxury awaits at this hotel with spa, restaurant, and contemporary art steps from the river.
The price is ￥23,866
￥28,865 total
includes taxes & fees
Nov 22 - Nov 23
21c Museum Hotel Louisville
A grand entrance with a staircase leading to a door, flanked by two lamp posts and a bench.

3. The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B
4.0 star property
New Albany
9.8 out of 10, Exceptional, (739 reviews)
The price is ￥14,718
￥16,631 total
includes taxes & fees
Oct 27 - Oct 28
The Pepin Mansion Historic B&B
A bedroom with a large bed, a wooden floor, a white door, and a painting on the wall.

4. Eclectic & Unique Historic Home

Eclectic & Unique Historic Home
New Albany
8.0 out of 10, Very good, (5 reviews)
The price is ￥27,452
￥75,514 total
includes taxes & fees
Oct 27 - Oct 28
Eclectic & Unique Historic Home
A grand staircase with a wooden handrail and carpeted steps, leading to an upper floor.

5. Louisville Bourbon Inn

Louisville Bourbon Inn
5.0 star property
Old Louisville
10.0 out of 10, Exceptional, (25 reviews)
  • cleanliness
    Luxurious bourbon country retreat offers elegant rooms with Egyptian cotton sheets and champagne service just minutes from downtown.
The price is ￥43,767
￥50,802 total
includes taxes & fees
Oct 27 - Oct 28
Louisville Bourbon Inn
A wooden deck with a table, chairs, and a lantern.

6. Inn at Woodhaven

Inn at Woodhaven
5.0 star property
St. Matthews
9.8 out of 10, Exceptional, (41 reviews)
The price is ￥37,461
￥43,482 total
includes taxes & fees
Nov 1 - Nov 2
Inn at Woodhaven
Property grounds

7. Creation Museum Hot Tub 4BR for 10

Creation Museum Hot Tub 4BR for 10
4.5 star property
Burlington
The price is ￥46,697
￥91,951 total
includes taxes & fees
Nov 1 - Nov 2
Creation Museum Hot Tub 4BR for 10
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Southern Indiana Hotel Reviews

Hampton Inn New Albany Louisville West

Hampton Inn New Albany Louisville West

10/10 Excellent
"Clean,breakfast and right off the interstate. Local restaurants and gas stations."
Doug 1-night trip
Posted 7 hours ago
Hampton Inn New Albany Louisville West
Hampton Inn Evansville/Airport

Hampton Inn Evansville/Airport

10/10 Excellent
"H"
robert 1-night trip
Posted 6 days ago
Hampton Inn Evansville/Airport