The Best Luxury Hotels in Southeastern Indiana from ￥20,996 in 2026 | Expedia

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Check availability on Southeastern Indiana Luxury Hotels

Tonight

Oct 16 - Oct 17

Tomorrow

Oct 17 - Oct 18

This weekend

Oct 16 - Oct 18

Next weekend

Oct 23 - Oct 25

Our top choices for Southeastern Indiana luxury hotels

A grand lobby with ornate columns, plush seating, and a chandelier.

A grand lobby with ornate ceiling, multiple seating areas, and a staircase.

A grand dining area with ornate ceiling, chandeliers, and a bar area with a sign reading "Cigar Bar".

A grand lobby with ornate ceiling, large windows, and classic furniture.

1. The Brown Hotel

Downtown Louisville

Elegantly designed spaces and refined comforts define this historic Louisville hotel offering a boutique feel in the city center.

￥19,808

￥23,307 total

includes taxes & fees

Oct 28 - Oct 29

A classical gold statue in front of a multi-story building with large windows and a brick facade.

A cozy room with a geometric-patterned ceiling, a sofa, and a chair.

A cozy room with wooden walls, a table with a lamp, and shelves displaying books and decorative items.

A restaurant with multiple dining tables, a long bench seating area, and framed artwork on the walls.

2. 21c Museum Hotel Louisville

Downtown Louisville

Museum-infused luxury awaits at this hotel with spa, restaurant, and contemporary art steps from the river.

￥24,053

￥29,092 total

includes taxes & fees

Nov 8 - Nov 9

A grand entrance with a staircase leading to a door, flanked by two lamp posts and a bench.

A marble countertop with a tray of colorful glassware, a bottle, and two glasses. A framed painting hangs above, and two lamps are on either side.

A covered porch with a brick wall, a wooden door, and a hanging light fixture.

A grand hallway with a wooden floor, a staircase, a chandelier, and a large mirror.

3. The Pepin Mansion Historic B&B

New Albany

￥18,580

￥20,996 total

includes taxes & fees

Oct 29 - Oct 30

A bedroom with a large bed, a wooden floor, a white door, and a painting on the wall.

A modern kitchen with a central island, wooden bar stools, a black refrigerator, and white cabinetry.

A dining area with a piano, a large woven pendant light, and a patterned rug.

A living room with a dining area, white cabinetry, a flat-screen TV, and a large patterned rug.

4. Eclectic & Unique Historic Home

New Albany

￥27,668

￥76,643 total

includes taxes & fees

Oct 19 - Oct 20

A grand staircase with a wooden handrail and carpeted steps, leading to an upper floor.

A spacious dining area with a chandelier, a fireplace, and a view of greenery outside.

A covered outdoor seating area with wicker furniture and a wooden railing.

A living room with a sofa, armchair, coffee table, fireplace, and large windows.

5. Louisville Bourbon Inn

Old Louisville

Luxurious bourbon country retreat offers elegant rooms with Egyptian cotton sheets and champagne service just minutes from downtown.

￥44,105

￥51,193 total

includes taxes & fees

Oct 26 - Oct 27

A wooden deck with a table, chairs, and a lantern.

A grand staircase with dark wood railings and a chandelier.

A traditional room with a sofa, armchairs, a coffee table, and a sideboard.

A large, historic house with a green roof, multiple chimneys, and a prominent front porch.

6. Inn at Woodhaven

St. Matthews

￥37,754

￥43,822 total

includes taxes & fees

Nov 1 - Nov 2

View all properties

Top Southeastern Indiana Hotel Reviews

Hyatt Select Louisville North

Hyatt Select Louisville North

10/10 Excellent

"Very clean and very nice"

Sheraton Louisville Riverside by Marriott

Sheraton Louisville Riverside by Marriott

10/10 Excellent

"Rooms were really clean"

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