Find Resorts & Hotels with Spas in South Padre Island, TX

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Check availability on South Padre Island Resorts & Hotels with Spas

Tonight
Dec 26 - Dec 27
Tomorrow
Dec 27 - Dec 28
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

Our top choices for South Padre Island hotels with a spa

Body treatments, hydrotherapy, aromatherapy, deep-tissue massages
Margaritaville Beach Resort South Padre Island

Margaritaville Beach Resort South Padre Island

Margaritaville Beach Resort South Padre Island
4.0 star property
South Padre Island
8.6 out of 10, Excellent, (1928)
"The stay was amazing!"
United States
Marlyn
The price is ￥9,041
￥11,953 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Margaritaville Beach Resort South Padre Island
Exterior
Peninsula Island Resort & Spa - Beach Front Property at South Padre Island

Peninsula Island Resort & Spa - Beach Front Property at South Padre Island

Peninsula Island Resort & Spa - Beach Front Property at South Padre Island
3.5 star property
South Padre Island
7.4 out of 10, Good, (1002)
"The property is amazing 😍"
United States
tania
Peninsula Island Resort & Spa - Beach Front Property at South Padre Island
TV
Two Bedroom Apt on Tropical Paradise SPI

Two Bedroom Apt on Tropical Paradise SPI

Two Bedroom Apt on Tropical Paradise SPI
South Padre Island
The price is ￥46,626
￥67,090 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Two Bedroom Apt on Tropical Paradise SPI
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top South Padre Island Hotel Reviews

Sunchase Inn & Suites

Sunchase Inn & Suites

10/10 Excellent
"Room was amazing "
Leyla 2-night trip
Posted 4 days ago
Sunchase Inn & Suites

Frequently asked questions

Looking for a spa hotel in South Padre Island?
Book one of our wonderful spa hotels and treat yourself from the moment you arrive. Travelers love the beaches in South Padre Island. Be sure to enjoy the seafood restaurants during your stay. Hotels with spas are a great way to break away from your daily routine and add a layer of luxury to your weekend away.
What is the best spa hotel in South Padre Island?
Margaritaville Beach Resort South Padre Island is a top beach spa hotel featuring a fitness center, a bar, an outdoor pool, and a restaurant. Treat yourself to a facial, body scrub, or Swedish massage at the onsite spa.
How many spa hotels will I find in South Padre Island?
Among Expedia's 2812 accommodation options in South Padre Island, there is 1 spa hotel.
What's there to see and do in South Padre Island?
Experience all that South Padre Island has to offer when you visit South Padre Island Beach, Sea Turtle Inc, and South Padre Island Birding and Nature Center. If you have extra time while you're in the area, you might want to stop by Beach Park at Isla Blanca and Isla Blanca Park.
What is a South Padre Island spa hotel?
Spa hotels in South Padre Island provide lodging and have a full on-site spa which offers services such as therapies as well as beauty treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.