Santiago Vacations from ￥201,396
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The Latest Santiago Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Central Hotel Panama Casco Viejo
Casco Viejo
￥229,168
per person
Nov 26 - Nov 29
found 13 hours ago
Roundtrip flight included
Indianapolis (IND) to Panama City (PTY)
9.2/10 Wonderful! (1,001 reviews)
The hotel is in a really good location, is fairly clean, the breakfast buffet is really nice and the rooms are fairly clean and comfortable. However; I felt a bit disappointed that the hotel management wants to just focus on making money. I stayed here for a entire week and I told them that on my last day, my flight is later in the evening and if they could allow me to check out a bit later in the afternoon. They flat out refused and asked for $100 to let me check out at 4 pm. That tells me that it wasn't a availability issue because they were willing to let me stay till 4 pm for a extra $100. This is bad business. If I stayed for just a couple of days, that would have been a different story. I stayed at this hotel for a full week and paid around $1000 for my stay - showing some courtesy to the hotel guests and allowing them to checkout a bit later goes a long way to build goodwill and earn more business.
Reviewed on Sep 1, 2026
Megapolis Hotel Panamá
San Francisco
￥210,648
per person
Nov 26 - Nov 29
found 13 hours ago
Roundtrip flight included
Indianapolis (IND) to Panama City (PTY)
8.4/10 Very Good! (1,671 reviews)
Our stay was very comfortable at the Megapolis. We were 2 adults and 2 children in a deluxe room with 2 beds. There was a mini fridge with refreshments and snacks upon arrival and water was replenished everyday.. The buffet breakfast selection was vast and the sky walk connecting to the mall was very convenient but there were stairs so going with a stroller was difficult. The hotel decor was very impressive however some of the furniture appeared to be in disrepair and the hallway carpets on our floor needed to be vacuumed as there was visible dirt, even right outside our door, for the duration of our stay.
Overall I would definitely stay here again.
Reviewed on Sep 1, 2026
Find the Best Santiago Vacation Packages
Santiago Hotel Deals
Hotel Gran David
Vía Interamericana Santiago Veraguas
Fully refundableReserve now, pay when you stay
￥11,149
￥12,310 total
Sep 10 - Sep 11
includes taxes & fees
8.6/10 Excellent! (431 reviews)
"Although road side, this hotel is a gem. Old fashioned but well appointed. Staff were friendly and helpful. Included breakfast was good. Had a nice pool and gym."
Reviewed on Aug 31, 2026
HOTEL CORPORATIVO PLAZA COROTÚ
Carr. Panamericana Santiago Provincia de Veraguas
Minutes from downtown Santiago, Chicho Fábrega hospital and Universidad Latina.
Panama Panamá
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Santiago attractions
Escuela Normal Juan Demostenes Arosemena
9.2/10 (9 reviews)
Explore the campus of Escuela Normal Juan Demostenes Arosemena, during your trip to Santiago. Stroll along the lakeside or visit the cathedral while you're in the area.
Omar Torrijos Herrera Stadium
8.4/10 (9 reviews)
Catch an event at Omar Torrijos Herrera Stadium during your trip to Santiago. Amble around the area's lakeside or visit its cathedral.
Catedral of Santiago Apostol
8.8/10 (13 reviews)
Find out about the history of Santiago when you take a trip to Catedral of Santiago Apostol. Amble around the area's lakeside or visit its cathedral.
Plaza Banconal
8.6/10 (12 reviews)
You can find the perfect gifts to bring home at Plaza Banconal during your stay in Santiago. Stroll along the lakeside or visit the cathedral while you're in the area.
Frequently asked questions
How much does a Santiago vacation package cost?
You can pick up a vacation package to this popular destination from ￥201,396 on Expedia. But how much your vacation to Santiago costs will depend on the length of stay, season and hotel choice.
What are the cheapest months to go to Santiago?
If you're hoping to book a cheap Santiago vacation package, consider planning a trip in September, October and November. You'll typically find better prices on flights and accommodations during these months — perfect for a budget-friendly getaway.
How many days is enough for Santiago?
Typically, a handful of days is enough to explore the main attractions during your Santiago vacation. But if you'd like to have some time to unwind or take day trips, consider extending your trip.
Is it worth booking a vacation package to Santiago?
Whether you're planning to explore attractions such as Parque Acuatico Italia Guadalupe Panama and Escuela Normal Juan Demostenes Arosemena, or want to experience its terrific shopping and culture, a Santiago vacation will leave you with lasting memories. Book your getaway with Expedia and find out why Santiago is such a good vacation destination.
How to find the best Santiago package deals?
Start your search for a Santiago package deal by entering your destination and travel dates under our "Packages" tab. Then add some filters, like "Property type" and "Amenities," to fine-tune the results to your exact needs. You can also sort by "Package discount" and discover offers that come with huge savings. If you don't find the perfect Santiago package deal right away, simply switch up your dates and search again. Remember that deals are only available for a limited time, so book early and get your Santiago adventure underway.
Is it cheaper to book a Santiago vacation as a package?
An Expedia vacation package could land you significant savings when compared to arranging flights and accommodations separately. Better still, you can personalize your Santiago escape to match your exact needs. Choose your preferred flight time, select the hotel type and add a rental car. Browse our great deals to see how much you can save.
When to book a vacation package to Santiago?
Enjoy incredible discounts by reserving your flights ahead of time with Expedia. If being spontaneous is more your thing, take advantage of our last-minute deals for a spur-of-the-moment Santiago trip.
How to plan a trip to Santiago?
- Choose when to travel: Check your diary and get your bags packed. Your favorite season and the activities available will also help you decide when to visit Santiago.
- Budget wisely: Besides the cost of your accommodations, you'll need to factor in other expenses too. These include food, flights and transportation. Also, set aside some extra funds for unexpected costs that may crop up during your trip to Santiago.
- Decide your trip length: Think about how long you want to spend exploring Santiago. Plan your days so you can get to all the experiences and attractions you're interested in at a leisurely pace.
- Bundle your bookings: With your travel dates in place, you can combine your flights, car rental, hotels and more into a personalized Santiago vacation package.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
