Santiago Este Vacations from ¥314,032

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The Latest Santiago Este Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

Bella Vista
¥314,032
per person
Oct 2 - Oct 7
found 19 hours ago
Roundtrip non-stop flight included
Tokyo (TYO) to Panama City (PTY)
9/10 Wonderful! (5,778 reviews)
Megapolis Hotel Panamá

Megapolis Hotel Panamá

San Francisco
¥350,810
per person
Oct 2 - Oct 7
found 19 hours ago
Roundtrip non-stop flight included
Tokyo (TYO) to Panama City (PTY)
8.4/10 Very Good! (1,621 reviews)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Casco Viejo
¥324,971
per person
Oct 2 - Oct 7
found 19 hours ago
Roundtrip non-stop flight included
Tokyo (TYO) to Panama City (PTY)
9.2/10 Wonderful! (1,000 reviews)
This was a very beautiful hotel. The breakfast was absolutely amazing.

Reviewed on Aug 7, 2026

Hyatt Regency Panama City

Hyatt Regency Panama City

Bella Vista
¥329,498
per person
Oct 2 - Oct 7
found 19 hours ago
Roundtrip non-stop flight included
Tokyo (TYO) to Panama City (PTY)
9.6/10 Exceptional! (386 reviews)
Great atmosphere. Staff was very helpful when asking for directions and information, some more than others. Everything was clean. I really liked this hotel and my stay.

Reviewed on Aug 4, 2026

Las Clementinas

Las Clementinas

Casco Viejo
¥337,932
per person
Oct 2 - Oct 7
found 19 hours ago
Roundtrip non-stop flight included
Tokyo (TYO) to Panama City (PTY)
9.4/10 Exceptional! (199 reviews)
Very comfortable bed, cold air conditioning. The area felt very safe, being right across the street from the police station. Walkable to everything.

Reviewed on Aug 7, 2026

Find the Best Santiago Este Vacation Packages

Santiago Este Hotel Deals

Hotel Gran David

Hotel Gran David

Vía Interamericana Santiago Veraguas
Fully refundableReserve now, pay when you stay
¥9,084
¥10,020 total
Aug 13 - Aug 14
includes taxes & fees
8.6/10 Excellent! (419 reviews)
"Excelente"

Reviewed on Aug 7, 2026

Hotel Gran David
Hotel Mykonos Panama

Hotel Mykonos Panama

Panamerican Highway Nuevo Santiago Veraguas
Fully refundableReserve now, pay when you stay
¥17,344
¥19,118 total
Aug 10 - Aug 11
includes taxes & fees
8.8/10 Excellent! (592 reviews)
"Very well located"

Reviewed on Aug 2, 2026

Hotel Mykonos Panama
HOTEL VISTA LAGO

HOTEL VISTA LAGO

Rincón Largo La Pena Santiago de Veraguas
Fully refundableReserve now, pay when you stay
¥12,062
¥13,268 total
Aug 9 - Aug 10
includes taxes & fees
9.4/10 Exceptional! (121 reviews)
"We went to this hotel for the first time and it’s so amazing, excellent food nothing else to add"

Reviewed on Aug 3, 2026

HOTEL VISTA LAGO
See all 17 properties in Santiago Este
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What are the cheapest months to go to Santiago Este?
You can usually find lower prices and greater availability in August, September and October. Take a look at our cheap Santiago Este vacation packages and you could score some great off-season deals.
How many days is enough for Santiago Este?
Typically, a handful of days is enough to tick off the main sights during your Santiago Este vacation. However, if you'd like to have more time to chill out or take day tours, consider extending your itinerary.
How to find the best Santiago Este package deals?
Bagging a cheap Santiago Este package deal is a cinch with Expedia. After you've entered your travel dates and destination under our "Packages" tab, set your budget, apply a few filters and see what's available. You can personalize your search by "Popular locations," "Property type," "Guest rating" and more. Order the results by "Price: low to high" to discover the most economical Santiago Este package deals. Want a simple trick to get the biggest savings? Have some flexibility with your departure dates and consider traveling on a weekday, when prices are usually lower.
When to book a vacation package to Santiago Este?
If you're planning a spontaneous Santiago Este vacation, check out our last-minute deals that can be booked up to a week before you go. Don't want to leave things to the last minute? You can find amazing deals on your flights and hotels by booking ahead.
How to plan a trip to Santiago Este?
  1. Pick your dates: The things you want to do in Santiago Este and your favorite season will help you decide when to travel.
  2. Work out your budget: Ensure you have enough money to cover everything from transportation and meals to activities and airfares. Your hotel will likely be the largest expense during your trip to Santiago Este.
  3. Decide your trip length: Think about how long you'd like to spend discovering Santiago Este. Plan your days so you can get to all the attractions and activities you're interested in at a comfortable pace.
  4. Combine your airfare and accommodations: After you've nailed down your travel dates and duration, lock in the right Santiago Este vacation package for you.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.