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Oct 7 - Oct 8
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Oct 8 - Oct 9
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Oct 9 - Oct 11
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Our top choices for Santiago Este hotels

A pool area with lounge chairs and a covered seating area, surrounded by modern buildings.
A spacious lobby with a central water feature, multiple seating areas, and a curved ceiling with hanging lights.
A spacious lobby with modern seating, a central coffee table, and decorative hanging lights.
A modern hotel with a prominent entrance, outdoor seating area, and a handicap-accessible parking space.

1. Hotel Mykonos Panama

Hotel Mykonos Panama
Nuevo Santiago
United States
Ismael
￥13,359
￥14,780 total
includes taxes & fees
Oct 9 - Oct 10
Hotel Mykonos Panama
A pool surrounded by palm trees and a tiled roof structure.
A spacious room with a high ceiling, a large window, and a wooden door leading to another area. There are several potted plants and a small table with a vase.
A tree in a stone planter in a well-lit indoor space with a stone wall and a door in the background.
A hallway with a glass partition leading to a dining area, a stone wall, and a metal gate with decorative patterns.

2. Hotel Gran David

Hotel Gran David
Santiago
United States
Roxani
￥12,080
￥13,288 total
includes taxes & fees
Oct 8 - Oct 9
Hotel Gran David
A modern lobby with a sofa, armchairs, a desk, and a large window offering a view of the cityscape.
A lobby with a reception desk, two armchairs, a sofa, and a table with a lamp.
A bathroom with a tiled shower wall, a sink, and a towel rack.
A hotel room with two single beds, a desk with a chair, a television, and a door.

3. Hotel Plaza Los Tucanes

Hotel Plaza Los Tucanes
Nuevo Santiago
United States
James
￥8,186
￥9,005 total
includes taxes & fees
Oct 8 - Oct 9
Hotel Plaza Los Tucanes
A swimming pool with a water slide, surrounded by palm trees and lounge chairs.
A spacious dining area with high ceilings, large windows, and natural light. Tables are set with chairs and centerpieces.
A multi-story hotel with balconies, a pool, and a reflection in the water.
A modern bedroom with a large bed, a small table, and a chair. There is a window with curtains and a lamp on the wall.

4. HOTEL VISTA LAGO

HOTEL VISTA LAGO
La Pena
United States
Hedwig
￥11,355
￥12,563 total
includes taxes & fees
Oct 10 - Oct 11
HOTEL VISTA LAGO
A beach with a wide sandy shore and gentle waves.
A building with a thatched roof, a signboard with text, and a parked car.
A child crossing a rope bridge over water, with a person assisting.
A bedroom with a bed, a chair, a mirror, and an air conditioning unit.

5. olivias village room

olivias village room
Capellania
￥6,395
￥23,380 total
includes taxes & fees
Oct 8 - Oct 9
olivias village room
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Top Santiago Este Hotel Reviews

HOTEL VISTA LAGO

HOTEL VISTA LAGO

10/10 Excellent
"Todo perfecto"
Michele 2-night trip
Posted 3 weeks ago
HOTEL VISTA LAGO
Hotel Plaza Los Tucanes

Hotel Plaza Los Tucanes

10/10 Excellent
"Excelente"
Olopilel 1-night trip
Posted 2 months ago
Hotel Plaza Los Tucanes

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Frequently asked questions

Where is the best place for a stay in Santiago Este?
Located 14.9 mi (24 km) from the heart of Santiago Este, Hotel Mykonos Panama is a top choice for your stay based on our traveler data. Two other options for your stay in the area are Hotel Gran David and HOTEL VISTA LAGO. See all available top hotels, or vacation rentals in Santiago Este.
What's the top vacation rental that Santiago Este has to offer?
Minutes from downtown Santiago, Chicho Fábrega hospital and Universidad Latina.: Visitors like this Santiago Este vacation home rental. It is located in a rural location and offers a garden, air-conditioning, and laundry facilities to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchenette with a stovetop, a microwave, and a coffee maker, so you can cook with friends or family. See all vacation rentals in Santiago Este.
If I need to cancel my hotel reservation in Santiago Este, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santiago Este.
Where can I learn more about changing or cancelling my trip to Santiago Este?
For additional details about changing or cancelling your trip to Santiago Este, head over to our customer service page.
What is staying in Santiago Este like?
Travelers to Santiago Este will find plenty to explore and enjoy. There are 17 hotels and other accommodations in the surrounding area. Find out more about Santiago Este.
What is there to see in Santiago Este?
Places to visit in the wider area include Stella Sierra Regional Museum, Parque Acuatico Italia Guadalupe Panama, and Museum of Salt and Sugar. You'll also find Playa Bella Vista and Sarigua National Park in the area. Check out what more to see and do in Expedia's Santiago Este guide.
What's the weather like in Santiago Este?
The hottest months are usually March and April with an average temp of 80°F, while the coldest months are January and December with an average of 77°F. The rainiest months in Santiago Este are October, August, June, and November, with each month seeing an average of 18 inches of rainfall.