Find hotels in Santa Maria from ￥6,531

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Check prices for these dates

Tonight
Dec 23 - Dec 24
Tomorrow
Dec 24 - Dec 25
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

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Our top choices for Santa Maria hotels

Terrace/patio
Termas el Corazon

Termas el Corazon

Termas el Corazon
3.0 star property
Los Andes
7.2 out of 10, Good, (10)
"Perfect place to relax. Clean, quiet with great food and excellent service"
Canada
Jean-Luc
Termas el Corazon
Exterior detail
Inca Hoteles

Inca Hoteles

Inca Hoteles
3.5 star property
Los Andes
9.2 out of 10, Wonderful, (135)
"Restaurant and breakfast buffet are delicious! Rooms were perfect size and very clean. Staff is incredibly friendly and helpful. Easy drive to Portillo to ski! "
United States
CAMERON
The price is ￥17,259
￥17,259 total
Jan 6 - Jan 7, 2026
Inca Hoteles
Front of property
Hotel Genova

Hotel Genova

Hotel Genova
2.5 star property
Los Andes
7.2 out of 10, Good, (39)
"The staff wasn’t very friendly Good place to stay."
United States
Jose
The price is ￥6,531
￥6,531 total
Dec 28 - Dec 29
Hotel Genova
Seasonal outdoor pool, pool umbrellas, sun loungers
Casona El Resguardo

Casona El Resguardo

Casona El Resguardo
3.0 star property
San Esteban
9.6 out of 10, Exceptional, (5)
"Lovely stay in this BnB style hotel. The food was the best part! Excellent chef that makes a special meal nightly considering all dietary restrictions. Location close enough to Portillo Ski resort to drive for daily skiing. Highly recommend. "
United States
Anonymous traveler
The price is ￥21,741
￥21,741 total
Dec 25 - Dec 26
Casona El Resguardo
Economy Twin Room
Hotel y Cabañas Palomar - Caja los Andes

Hotel y Cabañas Palomar - Caja los Andes

Hotel y Cabañas Palomar - Caja los Andes
2.0 star property
San Felipe
9.4 out of 10, Exceptional, (3)
"Excelente "
Costa Rica
Anonymous traveler
The price is ￥11,099
￥11,099 total
Dec 30 - Dec 31
Hotel y Cabañas Palomar - Caja los Andes
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Santa Maria attractions

El Zaino Dreaming Stones

You can find out about the history of Santa Maria with a stop at El Zaino Dreaming Stones.
See properties

Top Santa Maria Hotel Reviews

Casona El Resguardo

Casona El Resguardo

10/10 Excellent
"Lovely stay in this BnB style hotel. The food was the best part! Excellent chef that makes a special meal nightly considering all dietary restrictions. Location close enough to Portillo Ski resort to drive for daily skiing. Highly recommend. "
Anonymous traveler 3-night trip
Posted 4 months ago
Casona El Resguardo

More cheap stays in Santa Maria

Hotel Genova

Hotel Genova

523 Las Heras Los Andes Región de Valparaíso
The price is ￥6,531 per night from Dec 28 to Dec 29
￥6,531
￥6,531 total
Dec 28 - Dec 29
7.2/10 Good! (39 reviews)

Frequently asked questions

Where is the best place to stay in Santa Maria?
Based on our traveler data, Termas Jahuel Hotel & Spa is one of the top choices for your stay. This hotel offers a full-service spa and a restaurant. Two other options for your stay in the area are Termas el Corazon and Hotel Genova. See all available top hotels, or vacation rentals in Santa Maria.
What are some of the best vacation rentals that Santa Maria has to offer?
Boutique-mountain-lodge, near to Santiago de Chile, managed by owners: This vacation home rental outside of Santa Maria offers a balcony, a garden, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and an oven, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games. See all vacation rentals in Santa Maria.
If I need to cancel my hotel reservation in Santa Maria, will I receive a refund?
Yes, the majority of hotel bookings are refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before check in. If your reservation is non-refundable, you may still be able to cancel and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Maria.
Where can I learn more about changing or cancelling my trip to Santa Maria?
For additional details about changing or cancelling your trip to Santa Maria, click here.
What's the best accommodation for an all-inclusive stay in Santa Maria?
Termas Jahuel Hotel & Spa is an all-inclusive hotel featuring a full-service spa and a health club, and a favorite with Expedia travelers. See more all-inclusive resorts in Santa Maria.
What's the best hotel for staying near Arturo Merino Benitez Airport (SCL)?
Holiday Inn Santiago - Airport Terminal is a popular 3.5-star hotel featuring free extended parking and a restaurant. It's located a short 0.1 mi (0.2 km) from Arturo Merino Benitez Airport. Other good choices near the airport include Hotel Diego de Almagro Aeropuerto - Santiago and City Express Santiago Aeropuerto.
What is staying in Santa Maria like?
Travelers to Santa Maria will find plenty to explore and enjoy. There are 23 hotels and other accommodations in the surrounding area. Find out more about Santa Maria.
What is there to see in Santa Maria?
A favorite place to visit is El Zaino Dreaming Stones. You'll also find Termas El Corazón and Museo Antiguo Monasterio del Espíritu Santo in the area. Check out what more to see and do in Expedia's Santa Maria guide.
What's the weather like in Santa Maria?
The hottest months are usually January and February with an average temp of 69°F, while the coldest months are July and June with an average of 50°F. Average annual precipitation for Santa Maria is 14 inches.