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Our top choices for Santa Maria hotels

Hotel del Parque

Hotel del Parque
4.5 star property
7 km from Santa Maria
9.8 out of 10, Exceptional, (112 reviews)
"Friendly staff. We arrived very early and they were ablemto accommodate an early check-in. The hotel is beautiful "
Canada
Victor
The price is ¥68,250
¥75,075 total
Apr 12 - Apr 13
Hotel del Parque

Hotel Río Guayas by Art Hotels Ecuador

Hotel Río Guayas by Art Hotels Ecuador
4.0 star property
Las Peñas, 7.9 km from Santa Maria
10.0 out of 10, Exceptional, (3 reviews)
"The staff was very friendly and helpful. The hotel is new and modern, it is a good place to relax and work. "
United States
Richard
The price is ¥54,409
¥60,527 total
Apr 12 - Apr 13
Hotel Río Guayas by Art Hotels Ecuador

Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG
3.5 star property
5.5 km from Santa Maria
9.4 out of 10, Exceptional, (1,010 reviews)
"Perfect hotel for my overnight layover. 24-hour room service; helpful staff; easy and easily available shuttle to the airport. Would stay again."
United States
Alexander
The price is ¥14,636
¥16,497 total
May 3 - May 4
Holiday Inn Guayaquil Airport by IHG

Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana
4.5 star property
Puerto Santa Ana, 7.5 km from Santa Maria
9.2 out of 10, Wonderful, (1,004 reviews)
"Attentive staff and excellent breakfast and amenities."
United States
Mario
The price is ¥15,893
¥17,880 total
Apr 26 - Apr 27
Wyndham Guayaquil Puerto Santa Ana

NP Hotel & Suites

NP Hotel & Suites
3.0 star property
5.6 km from Santa Maria
The price is ¥8,110
¥8,269 total
Apr 13 - Apr 14
NP Hotel & Suites

Iguanazu Bed & Breakfast

Iguanazu Bed & Breakfast
3.5 star property
3 km from Santa Maria
9.2 out of 10, Wonderful, (47 reviews)
"A lovely oasis in the city. Very relaxing and friendly service."
United States
Landy
The price is ¥9,307
¥10,397 total
Apr 12 - Apr 13
Iguanazu Bed & Breakfast

Sheraton Guayaquil Hotel

Sheraton Guayaquil Hotel
5.0 star property
Simón Bolívar, 4.8 km from Santa Maria
9.0 out of 10, Wonderful, (635 reviews)
"Very nice place to stay ! "
United States
Diana
The price is ¥14,318
¥16,148 total
Apr 11 - Apr 12
Sheraton Guayaquil Hotel

Hilton Colon Guayaquil

Hilton Colon Guayaquil
4.5 star property
Kennedy, 4.2 km from Santa Maria
8.8 out of 10, Excellent, (888 reviews)
"convenient place and clean"
United States
Allyson
The price is ¥17,271
¥19,396 total
Apr 19 - Apr 20
Hilton Colon Guayaquil

Oro Verde Guayaquil

Oro Verde Guayaquil
5.0 star property
Downtown Guayaquil, 6.9 km from Santa Maria
9.4 out of 10, Exceptional, (1,001 reviews)
"Great staff!"
United States
Jeanette
The price is ¥12,727
¥14,398 total
Apr 12 - Apr 13
Oro Verde Guayaquil

Hotel La Ria Durán

Hotel La Ria Durán
3.0 star property
9.8 km from Santa Maria
7.4 out of 10, Good, (20 reviews)
"Muy buena experiencia"
Ecuador
HERNAN
The price is ¥7,636
¥7,636 total
Apr 11 - Apr 12
Hotel La Ria Durán

Hotel Puerto Pacifico Guayaquil Airport

Hotel Puerto Pacifico Guayaquil Airport
4.0 star property
Garzota, 4.9 km from Santa Maria
8.6 out of 10, Excellent, (247 reviews)
"The staff was very kind and professional. The food was delicious."
United States
Glenda E
The price is ¥8,052
¥8,291 total
Apr 19 - Apr 20
Hotel Puerto Pacifico Guayaquil Airport

Luxva Hotel Boutique

Luxva Hotel Boutique
3.0 star property
Urdesa, 4.7 km from Santa Maria
9.4 out of 10, Exceptional, (179 reviews)
"Clean room, staff, location"
United States
Veronica
The price is ¥13,602
¥13,761 total
Apr 11 - Apr 12
Luxva Hotel Boutique

Villa Celeste - VC

Villa Celeste - VC
2.5 star property
9.3 km from Santa Maria
7.4 out of 10, Good, (13 reviews)
"It is a good place, they respect your privacity and has a good communication with tourist places "
Mexico
Moises Reque
The price is ¥2,520
¥2,520 total
Apr 11 - Apr 12
Villa Celeste - VC

Casa Veranda

Casa Veranda
2.5 star property
8.9 km from Santa Maria
The price is ¥4,610
¥4,610 total
Apr 19 - Apr 20
Casa Veranda

Grand Hotel Guayaquil, an Ascend Collection Hotel

Grand Hotel Guayaquil, an Ascend Collection Hotel
4.0 star property
Rocafuerte, 7.9 km from Santa Maria
9.2 out of 10, Wonderful, (1,003 reviews)
"Nice place to stay. "
United States
Joanna
The price is ¥11,454
¥12,838 total
Apr 22 - Apr 23
Grand Hotel Guayaquil, an Ascend Collection Hotel

TRYP by Wyndham Guayaquil Airport

TRYP by Wyndham Guayaquil Airport
4.5 star property
Simón Bolívar, 4.9 km from Santa Maria
9.0 out of 10, Wonderful, (1,005 reviews)
"Very pleasant hotel - great location and excellent staff - room quiet and clean"
United States
Charles
The price is ¥13,459
¥15,203 total
Apr 12 - Apr 13
TRYP by Wyndham Guayaquil Airport

Wyndham Garden Guayaquil

Wyndham Garden Guayaquil
3.5 star property
Simón Bolívar, 4.8 km from Santa Maria
9.2 out of 10, Wonderful, (1,001 reviews)
"Excellent choice of hotel. Easy access from airport, friendly staff and excellent breakfast."
United States
Gerald
The price is ¥11,884
¥13,311 total
Apr 26 - Apr 27
Wyndham Garden Guayaquil

Mansión del Río

Mansión del Río
3.5 star property
Las Peñas, 7.8 km from Santa Maria
8.8 out of 10, Excellent, (136 reviews)
"Breakfast was good. I enjoyed my scrambled eggs and toast "
United States
Caitlin
The price is ¥9,240
¥10,323 total
Apr 30 - May 1
Mansión del Río

DC Suites Aeropuerto

DC Suites Aeropuerto
3.0 star property
Simón Bolívar, 5.2 km from Santa Maria
9.0 out of 10, Wonderful, (615 reviews)
"Clean room and nice staff"
United States
JUAN BERNARDO
The price is ¥5,441
¥5,600 total
May 1 - May 2
DC Suites Aeropuerto

Guayacan Apart Hotel

Guayacan Apart Hotel
2.0 star property
Downtown Guayaquil, 7.6 km from Santa Maria
The price is ¥6,364
¥6,364 total
Apr 11 - Apr 12
Guayacan Apart Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Maria

Find the best Santa Maria areas and neighborhoods for the activities you enjoy most.

Ecuador

Though Ecuador might not have many top sights, you can venture to the surrounding area to see attractions like C.C. Riocentro Sur and Mall del Sur.

Downtown Guayaquil

Travelers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Central Market and Sports Federation of Guayas while you're in town.

Puerto Santa Ana

Well-liked for its restaurants and river views, you might stop by Santa Ana Hill and Numa Pompilio Llona Street while you're exploring Puerto Santa Ana and the surrounding neighborhoods.

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or World Trade Center while you're exploring the area.

Bolívar

While Bolívar isn't home to many top sights, Malecon Mall and Central Market are some notable places to visit nearby.

Top Santa Maria Hotel Reviews

Frequently asked questions

What is Santa Maria like?
Travelers are sure to enjoy a stay in Guayaquil's Santa Maria neighborhood.
If I need to cancel my hotel reservation in Santa Maria, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, it might still be possible to cancel it and be given a refund within 24 hours of your booking. Enter dates in and click on "Search", then filter by "fully refundable" to get the best options available in Santa Maria.
Where can I learn more about changing or cancelling my trip to Santa Maria?
For more information about changing or cancelling your trip to Santa Maria, go to https://www.expedia.com/service/.
What can I see and do in this Guayaquil neighborhood?
Salón de Eventos Rubi, City Mall, and Guayaquil Parrot are just a few of the places to visit in and around Santa Maria. La Rotonda Shopping Center and Santa Ana Port are also worth a visit when you're out sightseeing in Guayaquil.