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Our top choices for Santa Maria hotels

DC Suites Aeropuerto

DC Suites Aeropuerto
3.0 star property
Simón Bolívar, 5.2 km from Santa Maria
9.0 out of 10, Wonderful, (600 reviews)
"Great location and clean hotel"
United States
Elvin
DC Suites Aeropuerto

Villa Celeste - VC

Villa Celeste - VC
2.5 star property
9.3 km from Santa Maria
7.4 out of 10, Good, (13 reviews)
"It is a good place, they respect your privacity and has a good communication with tourist places "
Mexico
Moises Reque
The price is ¥2,425
¥2,425 total
Mar 6 - Mar 7
Villa Celeste - VC

Hotel Dorado

Hotel Dorado
2.0 star property
8.1 km from Santa Maria
8.8 out of 10, Excellent, (13 reviews)
"Great location! Great value "
United States
John
The price is ¥3,136
¥3,136 total
Feb 20 - Feb 21
Hotel Dorado

Tropical Inn

Tropical Inn
2.0 star property
9.2 km from Santa Maria
8.2 out of 10, Very Good, (16 reviews)
"for the price was good"
United States
Rosa
Tropical Inn

Casa Serena

Casa Serena
2.5 star property
Simón Bolívar, 4.9 km from Santa Maria
9.2 out of 10, Wonderful, (54 reviews)
"the property was ok for the price"
United States
ASONG
Casa Serena

Hotel Puerto Pacifico Guayaquil Airport

Hotel Puerto Pacifico Guayaquil Airport
4.0 star property
Garzota, 4.9 km from Santa Maria
8.8 out of 10, Excellent, (236 reviews)
"Great stay and great staff!"
United States
Jemima
Hotel Puerto Pacifico Guayaquil Airport

Harmonie

Harmonie
2.0 star property
Simón Bolívar, 4.8 km from Santa Maria
9.0 out of 10, Wonderful, (92 reviews)
"Friendly staff, great service! "
United States
Yerifer
The price is ¥4,640
¥4,640 total
Feb 26 - Feb 27
Harmonie

Hotel La Ria Durán

Hotel La Ria Durán
3.0 star property
9.8 km from Santa Maria
7.4 out of 10, Good, (20 reviews)
"Muy buena experiencia"
Ecuador
HERNAN
The price is ¥7,349
¥7,349 total
Feb 20 - Feb 21
Hotel La Ria Durán

MundialCity Hotel Guayaquil

MundialCity Hotel Guayaquil
3.0 star property
Simón Bolívar, 5.1 km from Santa Maria
8.4 out of 10, Very Good, (167 reviews)
"Room was great and very clean. The staff is amazingly friendly and nice. This will be my go to hotel from now on ."
United States
Gary
MundialCity Hotel Guayaquil

Casa Veranda

Casa Veranda
2.5 star property
8.9 km from Santa Maria
Casa Veranda

Iguanazu Bed & Breakfast

Iguanazu Bed & Breakfast
3.5 star property
3 km from Santa Maria
9.2 out of 10, Wonderful, (47 reviews)
"Excelente Todo "
Costa Rica
Cesar
The price is ¥8,778
¥9,827 total
Mar 15 - Mar 16
Iguanazu Bed & Breakfast

Pachamac House

Pachamac House
2.0 star property
6 km from Santa Maria
The price is ¥2,970
¥2,970 total
Mar 17 - Mar 18
Pachamac House

PRAGA APARTMENTS

PRAGA APARTMENTS
4.0 star property
Urdesa, 4.2 km from Santa Maria
9.2 out of 10, Wonderful, (17 reviews)
"The room was very nice and the employees were very friendly and helped me a lot. I would recommend my family and friends to stay here. It’s so nice and quiet here. "
Canada
Timothy
PRAGA APARTMENTS

Suitesecu Rentals Guayaquil

Suitesecu Rentals Guayaquil
4.5 star property
Garzota, 5.1 km from Santa Maria
9.2 out of 10, Wonderful, (11 reviews)
"You can walk to the airport."
United States
Digna
The price is ¥3,832
¥4,837 total
Mar 8 - Mar 9
Suitesecu Rentals Guayaquil

Hotel Varadero Internacional

Hotel Varadero Internacional
3.0 star property
Downtown Guayaquil, 6.6 km from Santa Maria
8.0 out of 10, Very Good, (67 reviews)
"Overall a good place to stay and close to most destinations."
United States
Daniel
Hotel Varadero Internacional

Ibis Styles El Malecon Guayaquil

Ibis Styles El Malecon Guayaquil
4.0 star property
Downtown Guayaquil, 8.1 km from Santa Maria
9.4 out of 10, Exceptional, (288 reviews)
"Excellent hotel! Spotless, convenient to the airport and right on the Malecon. Comfortable bed, warm shower, excellent breakfast, nice views and lovely staff."
United States
Claudia
The price is ¥9,186
¥10,335 total
Mar 14 - Mar 15
Ibis Styles El Malecon Guayaquil

Wyndham Garden Guayaquil

Wyndham Garden Guayaquil
3.5 star property
Simón Bolívar, 4.8 km from Santa Maria
9.2 out of 10, Wonderful, (1,000 reviews)
"Great room convenient location "
United States
Jorge
The price is ¥12,374
¥13,843 total
Feb 20 - Feb 21
Wyndham Garden Guayaquil

Mansión del Río

Mansión del Río
3.5 star property
Las Peñas, 7.8 km from Santa Maria
8.8 out of 10, Excellent, (136 reviews)
"Breakfast was good. I enjoyed my scrambled eggs and toast "
United States
Caitlin
The price is ¥9,094
¥10,157 total
Mar 16 - Mar 17
Mansión del Río

Hotel Las Peñas

Hotel Las Peñas
3.0 star property
Rocafuerte, 7.7 km from Santa Maria
8.4 out of 10, Very Good, (107 reviews)
"The air conditioning was great and the location was very good."
United States
Rommel
Hotel Las Peñas

Hotel GH Sander

Hotel GH Sander
3.0 star property
Rocafuerte, 7.3 km from Santa Maria
8.8 out of 10, Excellent, (15 reviews)
"great property. i would definitely come back again every time i come to guayaquil"
United States
George
Hotel GH Sander
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Maria

Find the best Santa Maria areas and neighborhoods for the activities you enjoy most.

Ecuador

Though Ecuador might not have many top sights, you can venture to the surrounding area to see attractions like C.C. Riocentro Sur and Mall del Sur.

Downtown Guayaquil

Travelers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Central Market and San Francisco Square while you're in town.

Puerto Santa Ana

Well-liked for its restaurants and river views, you might stop by Santa Ana Hill and Botanical Garden while you're exploring Puerto Santa Ana and the surrounding neighborhoods.

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or World Trade Center while you're exploring the area.

Bolívar

While Bolívar isn't home to many top sights, Malecon Mall and Central Market are some notable places to visit nearby.

Top Santa Maria Hotel Reviews

Frequently asked questions

What is Santa Maria like?
Travelers are sure to enjoy a stay in Guayaquil's Santa Maria neighborhood.
If I need to cancel my hotel reservation in Santa Maria, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, it might still be possible to cancel it and be given a refund within 24 hours of your booking. Enter dates in and click on "Search", then filter by "fully refundable" to get the best options available in Santa Maria.
Where can I learn more about changing or cancelling my trip to Santa Maria?
For more information about changing or cancelling your trip to Santa Maria, go to https://www.expedia.com/service/.
What can I see and do in this Guayaquil neighborhood?
Salón de Eventos Rubi, City Mall, and Guayaquil Parrot are just a few of the places to visit in and around Santa Maria. La Rotonda Shopping Center and Santa Ana Port are also worth a visit when you're out sightseeing in Guayaquil.