Find hotels in Santa Maria, Guayaquil from ￥4,521

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Discover 389 Santa Maria hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Wyndham Garden Guayaquil
Rooftop bar, alfresco dining, open daily

Wyndham Garden Guayaquil

3.5 star property
9.0 out of 10, Wonderful, (1000)
"great staff easy access and parking, nice location "
The price is ￥12,514
￥13,987 total
Oct 12 - Oct 13
Wyndham Garden Guayaquil
Holiday Inn Guayaquil Airport by IHG
Outdoor pool

Holiday Inn Guayaquil Airport by IHG

3.5 star property
9.2 out of 10, Wonderful, (1013)
"This was an absolutely fabulous hotel and stay from our arrival and pick up to the staff at the hotel to the restaurant wonderful!"
The price is ￥14,496
￥16,316 total
Oct 13 - Oct 14
Holiday Inn Guayaquil Airport by IHG
Sheraton Guayaquil Hotel
2 restaurants, breakfast, lunch, dinner served; Regional cuisine

Sheraton Guayaquil Hotel

5.0 star property
9.0 out of 10, Wonderful, (586)
"Excellent service from the staff and just seven minutes away from the airport. "
The price is ￥20,058
￥22,434 total
Nov 1 - Nov 2
Sheraton Guayaquil Hotel
Hotel Patrimonial by Greenfield
Outdoor pool, sun loungers

Hotel Patrimonial by Greenfield

3.5 star property
8.6 out of 10, Excellent, (128)
"Excellent location and close to the airport."
Hotel Patrimonial by Greenfield
Doubletree By Hilton Guayaquil
In-room safe, blackout drapes, soundproofing, iron/ironing board

Doubletree By Hilton Guayaquil

3.5 star property
9.0 out of 10, Wonderful, (50)
"The staff is amazing and the hotel is so beautiful."
The price is ￥11,190
￥12,457 total
Oct 12 - Oct 13
Doubletree By Hilton Guayaquil
TRYP by Wyndham Guayaquil Airport
Exterior

TRYP by Wyndham Guayaquil Airport

4.5 star property
8.8 out of 10, Excellent, (1009)
"Covenient, many options for dinning on premises. "
The price is ￥15,532
￥17,455 total
Oct 12 - Oct 13
TRYP by Wyndham Guayaquil Airport
DC Suites Aeropuerto
Lobby

DC Suites Aeropuerto

3.0 star property
9.0 out of 10, Wonderful, (558)
"Stayed for one night. Clean bathroom, easy to check in and very close to the airport. "
DC Suites Aeropuerto
Radisson Hotel Guayaquil
Outdoor pool, sun loungers

Radisson Hotel Guayaquil

5.0 star property
9.2 out of 10, Wonderful, (615)
"Excellent staff."
The price is ￥11,945
￥13,509 total
Nov 1 - Nov 2
Radisson Hotel Guayaquil
Iguanazu Bed & Breakfast
Exterior

Iguanazu Bed & Breakfast

3.5 star property
9.2 out of 10, Wonderful, (46)
"Swimming pool"
The price is ￥13,147
￥14,959 total
Oct 6 - Oct 7
Iguanazu Bed & Breakfast
Grand Hotel Guayaquil, an Ascend Collection Hotel
Outdoor pool, open 8:00 AM to 9:00 PM, sun loungers

Grand Hotel Guayaquil, an Ascend Collection Hotel

4.0 star property
9.2 out of 10, Wonderful, (959)
"Great place to Stay.!"
The price is ￥11,242
￥12,588 total
Oct 14 - Oct 15
Grand Hotel Guayaquil, an Ascend Collection Hotel
Ibis Styles El Malecon Guayaquil
Restaurant

Ibis Styles El Malecon Guayaquil

4.0 star property
9.4 out of 10, Exceptional, (254)
"Great location and great hotel "
The price is ￥8,875
￥9,984 total
Oct 11 - Oct 12
Ibis Styles El Malecon Guayaquil
Unipark by Oro Verde Hotels
Reception

Unipark by Oro Verde Hotels

4.0 star property
9.2 out of 10, Wonderful, (1009)
"I enjoyed much my staying in this hotel."
The price is ￥10,117
￥11,499 total
Oct 31 - Nov 1
Unipark by Oro Verde Hotels
Hotel GH Galeria
Exterior

Hotel GH Galeria

3.5 star property
8.4 out of 10, Very Good, (386)
"Location "
Hotel GH Galeria
Hotel Puerto Pacifico Guayaquil Airport
Massages

Hotel Puerto Pacifico Guayaquil Airport

4.0 star property
8.8 out of 10, Excellent, (210)
"Loved my stay. It was very clean and close to the airport. "
Hotel Puerto Pacifico Guayaquil Airport
Wyndham Guayaquil Puerto Santa Ana
Presidential Suite, 1 King Bed, Jetted Tub, River View | Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds

Wyndham Guayaquil Puerto Santa Ana

4.5 star property
9.2 out of 10, Wonderful, (1012)
"Very nice hotel "
The price is ￥16,241
￥18,235 total
Oct 12 - Oct 13
Wyndham Guayaquil Puerto Santa Ana
Courtyard by Marriott Guayaquil
Lobby

Courtyard by Marriott Guayaquil

3.5 star property
9.0 out of 10, Wonderful, (1004)
"Great stay "
The price is ￥11,094
￥12,425 total
Oct 10 - Oct 11
Courtyard by Marriott Guayaquil
Suitesecu Guayaquil
Executive Suite, Kitchenette, City View | Private kitchen | Microwave, electric kettle, griddle, cookware/dishes/utensils

Suitesecu Guayaquil

4.5 star property
9.6 out of 10, Exceptional, (5)
"Great place! Close to everything. Fast host. "
The price is ￥3,559
￥4,521 total
Oct 5 - Oct 6
Suitesecu Guayaquil
Hotel Palace Guayaquil
Lobby

Hotel Palace Guayaquil

4.0 star property
9.2 out of 10, Wonderful, (902)
"Good place to stay "
The price is ￥9,333
￥10,488 total
Oct 12 - Oct 13
Hotel Palace Guayaquil
Oro Verde Guayaquil
Children's activities

Oro Verde Guayaquil

5.0 star property
9.4 out of 10, Exceptional, (1000)
"Wonderful people,, great hotel . Very clean and comfortable stayed."
The price is ￥13,165
￥14,851 total
Oct 5 - Oct 6
Oro Verde Guayaquil
Hilton Colon Guayaquil
Lobby

Hilton Colon Guayaquil

4.5 star property
8.6 out of 10, Excellent, (773)
"Well located. Safe. Pool and spa were excellent. "
The price is ￥14,459
￥16,275 total
Oct 12 - Oct 13
Hilton Colon Guayaquil
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Santa Maria

Find the best Santa Maria areas and neighborhoods for the activities you enjoy most.

Downtown Guayaquil

Travelers come to Downtown Guayaquil for its abundant dining options, and you can see top attractions like Central Market and Sports Federation of Guayas while you're in town.

Ecuador

Though Ecuador might not have many top sights, you can venture to the surrounding area to see attractions like C.C. Riocentro Sur and Mall del Sur.

Puerto Santa Ana

Well-liked for its restaurants and river views, you might stop by Santa Ana Hill and La Perla while you're exploring Puerto Santa Ana and the surrounding neighborhoods.

Kennedy

Unique features of Kennedy include the shopping and restaurants. Make a stop by San Marino Mall or Policentro while you're exploring the area.

Urdesa

Urdesa is well-liked for its restaurants. If you'd like to do some sightseeing in the greater Guayaquil area, you might plan a trip to San Marino Mall or Policentro.

Top Santa Maria Hotel Reviews

Oro Verde Guayaquil

Oro Verde Guayaquil

10/10 Excellent
"The hotel was everything offered and more, the staff is extraordinary, from the outside security, front desk receptionists, servers throughout all the restaurants, housekeepers and more, these people know what it is to host. I’m planing my next trip to Ecuador and be certain that I won’t need to search for any other hotel, Oro Verde is it for me!!!"
Felix 9-night trip
Posted 5 days ago
Oro Verde Guayaquil

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Explore a world of travel with Expedia

Frequently asked questions

What is Santa Maria like?

Travelers are sure to enjoy a stay in Guayaquil's Santa Maria neighborhood.

If I need to cancel my hotel reservation in Santa Maria, will I receive a refund?

Yes, the majority of hotel bookings are fully refundable provided that you cancel before the hotel’s cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, it might still be possible to cancel it and be given a refund within 24 hours of your booking. Enter dates in and click on "Search", then filter by "fully refundable" to get the best options available in Santa Maria.

Where can I learn more about changing or cancelling my trip to Santa Maria?

For more information about changing or cancelling your trip to Santa Maria, go to https://www.expedia.com/service/.

What can I see and do in this Guayaquil neighborhood?

Salón de Eventos Rubi, City Mall, and Guayaquil Parrot are just a few of the places to visit in and around Santa Maria. La Rotonda Shopping Center and Santa Ana Port are also worth a visit when you're out sightseeing in Guayaquil.