Santa Lucia Vacation Rentals

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Check prices for these dates

In two weeks
Jan 2 - Jan 4
In two months
Feb 13 - Feb 15
In three months
Mar 13 - Mar 15
In four months
Apr 10 - Apr 12

Our top choices for Santa Lucia vacation rentals

Design Suite, 1 Bedroom, Bathtub | Memory foam beds, minibar, in-room safe, desk
Excellence Suite

Excellence Suite

Excellence Suite
Rome City Centre
8.4 out of 10, Very Good, (1039)
"The staff was very nice, the room was very clean and had everything I needed. The hotels location is in a great spot."
United States
Jennifer
Excellence Suite
Exterior detail
hu Roma Camping In Town

hu Roma Camping In Town

hu Roma Camping In Town
Gianicolense Suburb
8.2 out of 10, Very Good, (2399)
"Excellent staff & accommodations "
Canada
Luigi
The price is ￥7,705
￥9,584 total
includes taxes & fees
Jan 9 - Jan 10, 2026
hu Roma Camping In Town
Romantic Double or Twin Room, Terrace | Memory foam beds, in-room safe, individually decorated
Aenea Superior Inn

Aenea Superior Inn

Aenea Superior Inn
Rome City Centre
9.6 out of 10, Exceptional, (1002)
"Room was very clean and a great location"
Canada
Kelly
The price is ￥25,693
￥30,479 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Aenea Superior Inn
Apartment, 1 Bedroom, Terrace | Private kitchen
Tritone Top House

Tritone Top House

Tritone Top House
Rome City Centre
8.4 out of 10, Very Good, (628)
"Great location , room was a good size "
Australia
Rachel
The price is ￥10,511
￥13,409 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Tritone Top House
Free minibar, in-room safe, blackout drapes, soundproofing
Villa della Fonte - Trastevere

Villa della Fonte - Trastevere

Villa della Fonte - Trastevere
Rome City Centre
9.8 out of 10, Exceptional, (158)
"The staff was the best great loacation would definitely stay again"
United States
andrew
Villa della Fonte - Trastevere
Classic Double or Twin Room | Minibar, in-room safe, individually decorated, individually furnished
Palazzetto Trevi

Palazzetto Trevi

Palazzetto Trevi
Rome City Centre
9.4 out of 10, Exceptional, (223)
"The room was super clean and the TV had Netflix and Amazon, which was fab!"
United Kingdom
Natasha
Palazzetto Trevi
Property entrance
San Pietro Boutique Rooms

San Pietro Boutique Rooms

San Pietro Boutique Rooms
Rome City Centre
10.0 out of 10, Exceptional, (915)
"Great place to stay in Rome. Quiet and less crowded. "
United States
Tanya
San Pietro Boutique Rooms
Front of property
Tullia e Prisca Relais

Tullia e Prisca Relais

Tullia e Prisca Relais
Rome City Centre
9.2 out of 10, Wonderful, (573)
"Really nice staff and great room. We really enjoyed our stay!"
United States
Hannah
The price is ￥14,963
￥18,676 total
includes taxes & fees
Dec 22 - Dec 23
Tullia e Prisca Relais
Deluxe Studio Suite | Living area | 50-inch flat-screen TV with satellite channels, TV
Ara di Marte Suites

Ara di Marte Suites

Ara di Marte Suites
Rome City Centre
9.2 out of 10, Wonderful, (104)
"Loved the location and great staff"
United States
Earnell
The price is ￥21,111
￥25,439 total
includes taxes & fees
Dec 23 - Dec 24
Ara di Marte Suites
Rooftop terrace
Giuditta in Trastevere

Giuditta in Trastevere

Giuditta in Trastevere
Rome City Centre
9.6 out of 10, Exceptional, (264)
"Clean room, good location and fantastic staff "
United States
alberto
Giuditta in Trastevere
Double Room | Desk, free WiFi, bed sheets
La Piccola Maison

La Piccola Maison

La Piccola Maison
Rome City Centre
9.2 out of 10, Wonderful, (388)
"I found the area quiet and safe while I was walking in the night. I liked the fact that it was still walkable to a lot places I wanted to see."
Canada
Tonisha
The price is ￥17,381
￥20,966 total
includes taxes & fees
Jan 11 - Jan 12, 2026
La Piccola Maison
1 bedroom, premium bedding, in-room safe, desk
Capricci Romani

Capricci Romani

Capricci Romani
Rome City Centre
9.4 out of 10, Exceptional, (361)
"Really enjoyed the location and staff. Breakfast was amazing. "
United States
Raquel
Capricci Romani
Fountain
Relais Servio Tullio

Relais Servio Tullio

Relais Servio Tullio
Rome City Centre
9.0 out of 10, Wonderful, (387)
"We were very very comfortable here"
United States
Fiona
The price is ￥14,622
￥17,931 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Relais Servio Tullio
Amazzonia | In-room safe, blackout drapes, soundproofing, free WiFi
Camere IV Miglio

Camere IV Miglio

Camere IV Miglio
Cinecitta
9.6 out of 10, Exceptional, (11)
"Yes was very nice and quiet."
Canada
Ali Hassan
The price is ￥18,892
￥22,628 total
includes taxes & fees
Dec 22 - Dec 23
Camere IV Miglio
View from property
Colosseo Panoramic Rooms

Colosseo Panoramic Rooms

Colosseo Panoramic Rooms
Rome City Centre
9.4 out of 10, Exceptional, (476)
"Loved the amazing location and the friendly staff "
United States
Melissa
Colosseo Panoramic Rooms
Exterior
Numa Rome Trastevere

Numa Rome Trastevere

Numa Rome Trastevere
Gianicolense
9.2 out of 10, Wonderful, (60)
"Clean room, great amenities, good location"
Germany
Efthimios-Enias
The price is ￥13,998
￥17,615 total
includes taxes & fees
Jan 14 - Jan 15, 2026
Numa Rome Trastevere
Double or Twin Room | Frette Italian sheets, premium bedding, memory foam beds, minibar
Star Vatican Rooms

Star Vatican Rooms

Star Vatican Rooms
Rome City Centre
8.0 out of 10, Very Good, (593)
"Great place , clean and close to main attractions "
United States
Leonel
Star Vatican Rooms
Premium bedding, down comforters, memory foam beds, minibar
The Bridge Suites

The Bridge Suites

The Bridge Suites
Rome City Centre
9.2 out of 10, Wonderful, (230)
"Staff was great!"
United States
Philipp
The Bridge Suites
Romantic Studio Suite, Hot Tub | Egyptian cotton sheets, premium bedding, minibar, in-room safe
Navona Central Suites

Navona Central Suites

Navona Central Suites
Rome City Centre
9.0 out of 10, Wonderful, (273)
"We had a great stay!"
United States
Christopher
The price is ￥20,955
￥25,267 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Navona Central Suites
Premium bedding, minibar, in-room safe, desk
Relais La Maison De Luxe

Relais La Maison De Luxe

Relais La Maison De Luxe
Rome City Centre
9.2 out of 10, Wonderful, (259)
"Service staff were extremely helpful with providing suggestion on where to eat or get the best view of Rome!"
United States
Richard
The price is ￥14,811
￥18,510 total
includes taxes & fees
Jan 14 - Jan 15, 2026
Relais La Maison De Luxe
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Lucia Hotel Reviews

Trastevere Roma | UNA Esperienze

Trastevere Roma | UNA Esperienze

10/10 Excellent
"Amazing area! We looked for months on where to stay and this place was not in the location we were looking but so happy with our choice. It’s not overly touristy with great local vibe and day and night life. We were able to walk across the river every day for all the big atttractions. Hotel is clean, staff is accommodating. We would definitely return "
Kendall 9-night trip
Posted 12 hours ago
Trastevere Roma | UNA Esperienze

Find out more about Santa Lucia

Search for holiday rentals in Santa Lucia on Expedia! You can easily find your home rentals, villas, holiday apartments in Santa Lucia using one of the methods below:

  • View our selection of featured holiday rentals in Santa Lucia
  • Use the map to find apartments and other holiday homes in the Santa Lucia neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Santa Lucia while they last

Look no further and take a look at our great range of rental properties in Santa Lucia!

Frequently asked questions

Can I find a vacation rental in Santa Lucia?

Yes, there are vacation rentals near popular sights in Santa Lucia, or you can choose a more secluded option if you're looking for a relaxing stay.

What are some of the best vacation rentals that Santa Lucia has to offer?

Oriana Homèl Roma: This vacation home rental outside of Santa Lucia is in the city center and equipped with air-conditioning and WiFi to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave.

What’s there to see and do in Santa Lucia?

Explore the area and family-friendly sights such as Bioparco di Roma, or get out into nature at a spot like Villa Borghese. While in the area, you can also visit popular places like Trevi Fountain and Colosseum.

What’s a vacation rental in Santa Lucia like?

Vacation rentals are private properties where you can stay for a few weeks or just a few days in Santa Lucia. Vacation rentals offer amenities such as hot tubs, fire pits, and patios so you'll have all the comforts of home. If you're concerned about cleanliness, vacation rentals can provide a sense of seclusion away from public hotel elevators and busy reception areas while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is a great option for families.