Find Boutique Hotels in Santa Fe

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Santa Fe Boutique Hotels

Our top choices for Santa Fe boutique hotels

Rooftop terrace
Casa Decu

Casa Decu

Casa Decu
4.0 star property
La Condesa
9.4 out of 10, Exceptional, (813)
"Clean rooms, the staff was helpful and courteous.The bathrooms are a bit tight - but for the price its hard to complain. "
United States
Walid
Casa Decu
Rooftop terrace
Maria Condesa

Maria Condesa

Maria Condesa
4.0 star property
La Condesa
8.8 out of 10, Excellent, (804)
"Great staff "
United States
Jeffrey
The price is ￥14,388
￥17,194 total
includes taxes & fees
Dec 16 - Dec 17
Maria Condesa
Exterior
Hotel Carlota

Hotel Carlota

Hotel Carlota
3.5 star property
Reforma
8.4 out of 10, Very Good, (571)
"Overall good "
Mexico
HSIN HAN
The price is ￥12,507
￥15,216 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Hotel Carlota
Breakfast, lunch, dinner served; international cuisine
Downtown Mexico, a Member of Design Hotels

Downtown Mexico, a Member of Design Hotels

Downtown Mexico, a Member of Design Hotels
4.0 star property
Historic Center
8.8 out of 10, Excellent, (443)
"Historical property with spacious rooms and a lot of style. Excellent restaurant and boutique shops in the same building. Friendly and accommodating service."
United States
Robert
The price is ￥31,162
￥37,239 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Downtown Mexico, a Member of Design Hotels
Bar (on property)
Habita, Mexico City, a Member of Design Hotels

Habita, Mexico City, a Member of Design Hotels

Habita, Mexico City, a Member of Design Hotels
4.0 star property
Polanco
7.8 out of 10, Good, (360)
"Conveniently located and comfortable."
United States
Belinda
The price is ￥28,046
￥33,515 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Habita, Mexico City, a Member of Design Hotels
Lobby
The Green Park Hotel

The Green Park Hotel

The Green Park Hotel
4.0 star property
Miguel Hidalgo
8.6 out of 10, Excellent, (561)
"Great place, friendly staff and conveniently located to many great locations "
United States
Ernesto
The price is ￥27,835
￥33,263 total
includes taxes & fees
Dec 15 - Dec 16
The Green Park Hotel
Polaris Suite | View from room
La Valise Mexico City, Member of Small Luxury Hotels

La Valise Mexico City, Member of Small Luxury Hotels

La Valise Mexico City, Member of Small Luxury Hotels
5.0 star property
Roma Norte
9.6 out of 10, Exceptional, (49)
"Incredible experience at this hotel - the room was wonderful, the location was perfect, and the staff were the best! "
Canada
Aram
The price is ￥74,974
￥95,826 total
includes taxes & fees
Jan 12 - Jan 13, 2026
La Valise Mexico City, Member of Small Luxury Hotels
Staircase
Las Alcobas, a Luxury Collection Hotel, Mexico City

Las Alcobas, a Luxury Collection Hotel, Mexico City

Las Alcobas, a Luxury Collection Hotel, Mexico City
5.0 star property
Polanco
9.8 out of 10, Exceptional, (290)
"Beautifully located and very attentive staff."
Canada
Hussein
The price is ￥82,112
￥101,033 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Las Alcobas, a Luxury Collection Hotel, Mexico City
Free daily full breakfast
Casa Goliana La Roma

Casa Goliana La Roma

Casa Goliana La Roma
4.0 star property
Roma Norte
9.4 out of 10, Exceptional, (90)
"Such nice hosts, beautiful property, delicious breakfast "
United States
Rina
Casa Goliana La Roma
Terrace/patio
Las Suites Campos Eliseos

Las Suites Campos Eliseos

Las Suites Campos Eliseos
4.0 star property
Polanco
9.2 out of 10, Wonderful, (1349)
"The staff was top notch"
United States
Alan
The price is ￥25,174
￥30,083 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Las Suites Campos Eliseos
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Santa Fe Hotel Reviews

Zocalo Central & Rooftop Mexico City

Zocalo Central & Rooftop Mexico City

10/10 Excellent
"Staff was excellent and responded immediately to any requests. We would definitely stay here again. "
Maria 5-night trip
Posted 2 days ago
Zocalo Central & Rooftop Mexico City

Explore a world of travel with Expedia

Frequently asked questions

What's the best boutique accommodation in Santa Fe?
Distrito Capital is a favorite property with our travelers looking for a stylish accommodation, and features 30 guestrooms, free breakfast, and free valet parking.
What's there to see and do in Santa Fe?
The shopping and restaurants are just some of the things to enjoy while you're in the area. Top activities and sights around Santa Fe include Paseo de la Reforma, Autódromo Hermanos Rodríguez, and Angel of Independence Monument. You might also want to see places like Zócalo, Basilica of Our Lady of Guadalupe, and Teatro Zentrika during your trip.
What's the best way to get to my boutique hotel in Santa Fe?
You have a few options for getting to Santa Fe. The closest major airport is Benito Juarez International Airport (MEX), which is located 12.5 mi (20.2 km) away. Nearby metro stations include Santa Fé Station and Vasco de Quiroga Station.