Santa Cruz Vacations & Trips
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to ￥109,000 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Santa Cruz Hotel Deals
Hotel Fiesta
Calle Moises Brito y Juan Montalvo Puerto Ayora Galapagos
￥24,934
￥24,934 total
Oct 14 - Oct 15
Hotel el descanso del Guia
Calle Delfin, Barrio el Mirador Puerto Ayora Galapagos
￥11,578
￥11,578 total
Oct 29 - Oct 30
8.8/10 Excellent! (234 reviews)
"Espectacular la atención de los recepcionistas, del personal de limpieza y de la persona que atiende en el restaurante. Muchísimas gracias por todo"
Reviewed on Oct 10, 2026
Maidith Galapagos Inn
Calle Cucuve #341 y Seymour, Santa Cruz Puerto Ayora Galápagos
￥17,439
￥17,439 total
Oct 23 - Oct 24
10/10 Exceptional! (168 reviews)
"me gusto el hotel, es comodo, esta bien ubicado, el dueño esta siempre ahi, te ayudan en todo lo que puedan, ya tiene sus añitos el hotel pero esta bien cuidado, es comodo, no es para nada elegante, mas bien es acogedor, comodo, mas intimo, con personal local amables, cuidado, seguro, limpio."
Reviewed on Oct 12, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
How much does a Santa Cruz vacation package cost?
Handcraft your Santa Cruz vacation package from as little as . Pick from any combination of hotels, flights and rental cars to build the escape you've been dreaming about for ages. Be sure to add on a few experiences or activities!
How do I get a cheap travel package to Santa Cruz?
Our Santa Cruz vacation packages offer plenty of savings for the savvy globetrotter. For the best deal, simply bundle your hotel, flights and extras (such as activities) into an affordable package. But low prices are just the beginning of your next amazing adventure. Book with Expedia and and you'll have over 550 airlines and 1,000,000 hotels throughout the world to pick from. Whatever your style, there's a vacation package that's perfect for you.
How far in advance should I book my Santa Cruz vacation?
To bag cheap prices, book ASAP. Airlines typically advertise flights, along with some of the lowest fares, nearly a year ahead of time. Hotels, car rental and experiences should also be booked well in advance to avoid disappointment. If you've decided on a last-minute getaway in Santa Cruz, there are always plenty of great bargains to be had on Expedia. Check them out now!
What does an Expedia Santa Cruz travel package include?
Rental cars, flights and hotels, or any combination of the three — the choice is yours. Whether you're exploring Santa Cruz with the whole family or adventuring solo, there's a package to suit your style and budget. Once you've made your booking, why not add on a couple of activities?
What should I know before booking a Santa Cruz travel package?
Get set to save with an Expedia travel package. Combine your airfares, rental cars and hotels and be rewarded with exciting discounts. Hotels aren't your only choice, though. We have oceanfront condos, creek-side mountain cabins and even glamping tents!
Can I choose my airline with a Santa Cruz Expedia vacation package?
Yes, and with more than 550 airlines to select from around the world, you've got lots of choice. Look through the available options and find out which airline suits your budget and needs.
If I'm not able to travel, can I cancel my Santa Cruz vacation package?
If your travel plans in Santa Cruz have changed, it's comforting to know that you can cancel your booking. If you made your booking less than 24 hours ago, you may be eligible to receive a refund. If your booking is older than that, your airline, hotel or car rental company may charge a fee. To find out more, visit our Customer Service Portal.
Stay near popular Santa Cruz attractions
Photo by Elizabeth Oates
Tortuga Bay Beach
9.6/10 (488 reviews)
If a restful vacation is part of your travel plans, Tortuga Bay Beach might be the perfect place to seek out during your trip to Bella Vista. While you're in the area, wander around the parks.
Photo by Luis Felipe
El Garrapatero Beach
9.2/10 (154 reviews)
Why not spend a carefree afternoon at El Garrapatero Beach during your travels in El Cascajo? While you're in the area, wander around the parks.
Playa de los Alemanes
8.8/10 (262 reviews)
If a restful vacation is part of your travel plans, Playa de los Alemanes might be the perfect place to seek out during your trip to Puerto Ayora. While you're here, you can savor the top-notch restaurants.
Malecon
9.2/10 (350 reviews)
You can find out about the history of Puerto Ayora with a visit to Malecon. Wander the waterfront and beaches in the area.
Los Gemelos Sinkholes
9.2/10 (143 reviews)
Commune with nature and explore the great outdoors at Los Gemelos Sinkholes during your travels in Santa Rosa. Wander the waterfront and beaches in the area.
What to do in Santa Cruz
El Chato 2 Reserve Admission Ticket in Santa Cruz Island
￥1,255
per traveler
Bay Tour in Santa Cruz - Galapagos Islands
￥9,413
per adult
100% of travellers recommend
Half Day Bay Tour in Santa Cruz Island
￥11,766
per adult
90% of travellers recommend
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
