Santa Cruz Vacations
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to ￥45,448 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Find the Best Santa Cruz Vacation Packages
Santa Cruz Hotel Deals
Calle Flora Hotel by Jalo
# 37-40 Calle 9A Medellín
Fully refundableReserve now, pay when you stay
The price is ￥8,413 per night from Apr 15 to Apr 16
￥8,413
￥8,413 total
Apr 15 - Apr 16
9/10 Wonderful! (727 reviews)
Todo muy bonito y limpio, pero demasiado ruidoso el ambiente.
Reviewed on Apr 13, 2026
Hotel Dorado La 70
Carrera 70 No 44 B-66 Medellín
Fully refundableReserve now, pay when you stay
The price is ￥10,490 per night from Apr 28 to Apr 29
￥10,490
￥10,490 total
Apr 28 - Apr 29
8.8/10 Excellent! (1,871 reviews)
Ok
Reviewed on Apr 12, 2026
Hashtag 98 Hotel By Jalo
Carrera 41 # 10 - 37 Medellín Medellín
Fully refundableReserve now, pay when you stay
The price is ￥11,100 per night from May 11 to May 12
￥11,100
￥11,100 total
May 11 - May 12
9.2/10 Wonderful! (1,869 reviews)
Long list of issues won't be back
Reviewed on Apr 13, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Santa Cruz
Antioquia Museum
4.5/5(81 reviews)
Browse the original works of art on display by Medellin’s legendary artists Fernando Botero and Pedro Nel Gómez in the oldest museum in the state.
University of Antioquia
4.5/5(114 reviews)
Enjoy the collegiate vibe when you visit University of Antioquia, during your travels in Medellín. Check out the shops and top-notch restaurants in this walkable area.
What to do in Santa Cruz
Pablo Escobar Tour : Museum, History and Beer
￥6,348
per adult
90% of travellers recommend
Medellin: City Bike Tour with Colombian Drinks and Snacks
￥4,256
per adult
100% of travellers recommend
hiking medellin and hidden waterfalls
￥6,348
per adult
96% of travellers recommend
Explore a world of travel with Expedia
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
