Santa Cruz Vacations
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to ￥45,448 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
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Find the Best Santa Cruz Vacation Packages
Santa Cruz Hotel Deals
Calle Flora Hotel by Jalo
# 37-40 Calle 9A Medellín
Fully refundable
The price is ￥18,452 per night from Mar 3 to Mar 4
￥18,452
￥18,452 total
Mar 3 - Mar 4
9/10 Wonderful! (524 reviews)
Everything
Reviewed on Feb 26, 2026
Heiss Hotel By Jalo
1460 Cra. 43F Medellín Antioquia
Fully refundableReserve now, pay when you stay
The price is ￥10,893 per night from Mar 19 to Mar 20
￥10,893
￥10,893 total
Mar 19 - Mar 20
9.2/10 Wonderful! (1,229 reviews)
This hotel is a most, we enjoyed our stay.
Reviewed on Feb 25, 2026
Hotel Dorado La 70
Carrera 70 No 44 B-66 Medellín
Fully refundableReserve now, pay when you stay
8.8/10 Excellent! (1,852 reviews)
Excellent
Reviewed on Feb 24, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Santa Cruz
University of Antioquia
Enjoy the collegiate vibe when you visit University of Antioquia, during your travels in Medellín. Check out the shops and lively bars in this walkable area.
What to do in Santa Cruz
Pablo Escobar Tour : Museum, History and Beer
￥4,953
per adult
94% of travellers recommend
Medellin: City Bike Tour with Colombian Drinks and Snacks
￥4,605
per adult
100% of travellers recommend
hiking medellin and hidden waterfalls
￥6,191
per adult
96% of travellers recommend
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
