Santa Cruz Vacations

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to ￥109,000 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Find the Best Santa Cruz Vacation Packages

Santa Cruz Hotel Deals

Hashtag 98 Hotel By Jalo

Hashtag 98 Hotel By Jalo

4 out of 5
Carrera 41 # 10 - 37 Medellín Medellín
Fully refundableReserve now, pay when you stay
The price is ￥10,972 per night from Nov 10 to Nov 11
￥10,972
￥10,972 total
Nov 10 - Nov 11
9.2/10 Wonderful! (2,362 reviews)
"Exelente"

Reviewed on Nov 3, 2026

Hashtag 98 Hotel By Jalo
Calle Flora Hotel by Jalo

Calle Flora Hotel by Jalo

4 out of 5
# 37-40 Calle 9A Medellín
Fully refundableReserve now, pay when you stay
The price is ￥11,964 per night from Nov 9 to Nov 10
￥11,964
￥11,964 total
Nov 9 - Nov 10
Calle Flora Hotel by Jalo
Heiss Hotel By Jalo

Heiss Hotel By Jalo

4 out of 5
1460 Cra. 43F Medellín Antioquia
Fully refundableReserve now, pay when you stay
The price is ￥9,024 per night from Nov 10 to Nov 11
￥9,024
￥9,024 total
Nov 10 - Nov 11
Heiss Hotel By Jalo
See all 4,697 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

What to do in Santa Cruz

Medellin: Bike City Tour with Local Food and Drink Tastings

Medellin: City Bike Tour with Colombian Drinks and Snacks

￥4,884
per adult
100% of travellers recommend
Medellin: City Bike Tour with Colombian Drinks and Snacks
Medellin: Comuna 13 History & Graffiti Tour with Cable Car

Medellin: Comuna 13 Graffiti Tour, Cable Car & Street Food

￥3,158
per adult
88% of travellers recommend
Medellin: Comuna 13 Graffiti Tour, Cable Car & Street Food
Pablo Escobar Tour Museum History and Beer

Pablo Escobar Tour Museum History and Beer

￥6,269
per adult
92% of travellers recommend
Pablo Escobar Tour Museum History and Beer
See all activities in Santa Cruz

Frequently asked questions

How much does a Santa Cruz vacation package cost?
You can grab a vacation package to this top destination on Expedia. However, how much your vacation to Santa Cruz costs will depend on factors like the length of stay, season and hotel choice.
What are the cheapest months to go to Santa Cruz?
To score cheap Santa Cruz vacation packages, organize your getaway outside of busy periods like public holidays and major festivals. You'll generally find lower prices and better availability for flights and hotels.
How many days is enough for Santa Cruz?
The ideal length for your Santa Cruz vacation depends on what you'd like to see. Generally, a handful of days to a week will give you time to tick off all the major sights and discover some hidden treasures along the way.
How to find the best Santa Cruz package deals?
Start your search for a Santa Cruz package deal by entering your travel dates and destination under our "Packages" tab. Then add some filters, like "Guest rating" and "Property type," to fine-tune the results to your exact style. You can also sort by "Package discount" and browse offers that come with huge savings. If you don't find the perfect Santa Cruz package deal straight away, simply change your dates and search again. Remember that deals are only available for a limited time, so book early and get your Santa Cruz escape underway.
Is it cheaper to book a Santa Cruz vacation as a package?
An Expedia vacation package could score you significant savings when compared to booking accommodations and flights separately. Better still, you can personalize your Santa Cruz getaway to fit your exact needs. Pick your preferred flight time, select the hotel type and add a rental car. Explore our bundles to see how much you can save.
When to book a vacation package to Santa Cruz?
If you have your Santa Cruz vacation dates finalized, book as soon as you can to bag some incredible deals. With Expedia, you can generally reserve some flights up to one year in advance. Prefer spur-of-the-moment adventures? Our last-minute deals are perfect for traveling on a whim.
How to plan a trip to Santa Cruz?

  1. Choose the ideal time to travel: Your schedule, favorite season and the type of weather you like can all influence your decision on when to travel to Santa Cruz.
  2. Budget wisely: In addition to the price of your hotel, you should consider other expenses. These include transportation, food and flights. Also, set aside a little extra for unexpected costs that may arise during your trip to Santa Cruz.
  3. Decide how long to go away for: Now that you're up to speed on Santa Cruz, you can work out the ideal length of your vacation. Create a rough plan and allocate enough time to cover everything you want to see.
  4. Bundle your flights and hotel: Epic destination, check. Length of stay, check. All that's left now is to pick a Santa Cruz vacation package that brings all your bookings together.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.