Top 10 Hotels in Santa Cruz from ￥3,774 - Competitive Prices

A colonial-style building with a bell tower, palm trees, and a paved walkway.

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Pet friendly

Pool

Condo

Apartment

Spa

Hot tub

Family friendly

Waterpark

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Our top choices for Santa Cruz hotels

1. Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Equipetrol

ERNESTO

￥22,066

￥22,066 total

Oct 1 - Oct 2

2. Ibis Santa Cruz DE LA Sierra

Equipetrol

Hui Hua

￥6,967

￥6,967 total

Oct 2 - Oct 3

3. Marriott Santa Cruz de la Sierra Hotel

Santa Cruz

Deivis

￥16,249

￥16,249 total

Oct 2 - Oct 3

4. Camino Real Hotel

Santa Cruz

Wendy

￥22,399

￥22,399 total

Sep 14 - Sep 15

5. Hotel Cortez

Equipetrol

Leonora

￥17,275

￥17,275 total

Oct 13 - Oct 14

Panoramic Apartment, 1 King Bed with Sofa bed, Terrace

6. Premium Suites Deluxe Aparthotel Equipetrol

Santa Cruz

Luisa

￥7,066

￥7,066 total

Sep 15 - Sep 16

7. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Santa Cruz

Scott

￥11,306

￥11,306 total

Oct 2 - Oct 3

Premium Suite, 2 Queen Beds, Pool View | View from room

8. Sun Hotel

Santa Cruz

Ivan

￥15,007

￥15,007 total

Sep 18 - Sep 19

9. Delfines Collection Hotel By Mercure

Equipetrol

Mathetes

￥8,183

￥8,183 total

Sep 13 - Sep 14

10. TRYP by Wyndham Santa Cruz

Equipetrol

Pluetina

￥13,395

￥13,395 total

Sep 15 - Sep 16

11. Chairú Eco Hotel

Santa Cruz

Luis

￥7,570

￥7,570 total

Oct 5 - Oct 6

12. Novotel Santa Cruz De La Sierra

Santa Cruz

ERNESTO

￥18,986

￥18,986 total

Oct 1 - Oct 2

Comfort Double Room, 2 Queen Beds, Ensuite, City View

13. HOTEL OSHO

Santa Cruz

David

￥6,745

￥6,745 total

Sep 13 - Sep 14

14. Hotel Las Américas

Centro Histórico

Stanley

￥4,009

￥4,009 total

Sep 28 - Sep 29

15. Lido Hotel

Centro Histórico

Gabrielle

￥3,619

￥3,619 total

Sep 14 - Sep 15

16. Alfonsina Hotel Boutique by Inboccaluppo

Equipetrol

Elizabeth

￥16,560

￥16,560 total

Sep 30 - Oct 1

17. Hotel LP Equipetrol

Equipetrol

Ricardo

￥5,285

￥6,053 total

Oct 2 - Oct 3

18. Swissôtel Santa Cruz De La Sierra

Santa Cruz

GONZALO

￥20,154

￥20,154 total

Oct 8 - Oct 9

19. Cosmopolitano Hotel Boutique

Centro Histórico

Veronica

￥8,834

￥8,834 total

Sep 28 - Sep 29

20. Hotel LP Santa Cruz Centro

Santa Cruz

John

￥4,558

￥5,330 total

Sep 19 - Sep 20

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Vacation Rentals in Santa Cruz

Aparthotel

Premium Suites Deluxe Aparthotel Equipetrol

Santa Cruz

"great place to stay!"

Apartment

Business Apartment, 2 Bedrooms (Plus) | In-room dining

Apart Hotel Premium Suites Santa Cruz

Santa Cruz

"Great location."

Apartment

AMERICA APARTMENTS

Santa Cruz

"Clean room, great staff "

Aparthotel

Terranova Suites

Santa Cruz

"Easy to access"

Aparthotel

Standard Suite, 1 Queen Bed | Private kitchen

Equipetrol Suites Apart Hotel

Santa Cruz

"Perfect hotel"

Aparthotel

Apart Hotel Toborochi

Equipetrol

"Very comfortable and quiet place and very good location. "

Vacation Home

Casa Vida

Santa Cruz

"buena recepción, el lugar es muy bueno un poco alejado de la ciudad, falta comodidad en algunos aspectos pero la casa es grande y espaciosa"

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Where to stay in Santa Cruz

Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most.Learn more about Santa Cruz

Hamacas

While Hamacas isn't home to many top sights, Santa Cruz Zoo and Las Brisas Shopping Center are some notable places to visit nearby.

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Stay near popular Santa Cruz attractions

A historic building with arched windows and a clock. People are sitting and standing on the steps in front of the building.

Plaza 24 de Septiembre

8.8/10 (164 reviews)

Plaza 24 de Septiembre buzzes with local culture beneath swaying palms and colonial architecture. Climb the Cathedral's bell tower for spectacular city views while sampling authentic Bolivian coffee from vendors.

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An interior of a church with high arched ceilings, wooden pews, and a central altar.

San Lorenzo Cathedral

9.0/10 (84 reviews)

This grand neoclassical cathedral dominates Santa Cruz's skyline with its towering spires and ornate façade. Climb the bell tower at sunset for breathtaking panoramic views of the city.

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Ventura Mall

9.0/10 (183 reviews)

Ventura Mall, Santa Cruz's premier shopping destination, features international brands and local boutiques. Enjoy the cinema complex, food court, and entertainment options in this contemporary Bolivian retail hub.

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Guembe Biocenter

8.8/10 (60 reviews)

This vibrant ecological sanctuary showcases hundreds of butterfly species in a lush, tropical environment. Explore walking trails, enjoy boat rides, and learn about biodiversity in this serene natural retreat.

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Santa Cruz Zoo

8.4/10 (53 reviews)

The Santa Cruz Municipal Zoo showcases Bolivia's native wildlife in naturalistic habitats, featuring jaguars, tapirs, and free-ranging sloths. Morning visits offer the best chance to see active animals.

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Ramon Tahuichi Aguilera Stadium

8.4/10 (18 reviews)

This multi-purpose stadium hosts Bolivia's most passionate football rivalries and tournaments. Experience the electric atmosphere of a local derby while enjoying modernized facilities and vibrant Santa Cruz culture.

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Blacutt Square

8.2/10 (19 reviews)

Plaza Blacutt offers a verdant escape in Santa Cruz with mature trees shading tiled pathways. Enjoy local flavors from vendors along the northern edge while children play in the well-equipped playground areas.

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Cine Center

8.0/10 (53 reviews)

This premier entertainment complex offers state-of-the-art cinema experiences with immersive 4D E-Motion formats. Enjoy the latest films, then explore the shopping center and diverse dining options in the food court.

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Learn more about Santa Cruz

Tropical energy pulses through Plaza 24 de Septiembre, where locals gather under palm trees and the Metropolitan Cathedral's twin towers stand watch. Biocentro Güembé offers rainforest trails with butterfly gardens, while the massive Ventura Mall provides air-conditioned shopping when afternoon temperatures climb.

See all hotels in Santa Cruz

Top Santa Cruz Hotel Reviews

Ibis Santa Cruz DE LA Sierra

8/10 Good

"Muy buena variedad de alimentos"

Hotel Cortez

10/10 Excellent

"Awesome Hotel"

Sun Hotel

10/10 Excellent

"Very nice place to stay. Close to the airport with shuttle to the hotel."

TRYP by Wyndham Santa Cruz

10/10 Excellent

"We had a great stay here. The rooms were clean and comfortable. Will return!"

Camino Real Hotel

10/10 Excellent

"The food is excellent quality and delicious! Friendly staff"

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

10/10 Excellent

"The room was very clean and the breakfast was fantastic. Overall it was a great experience."

Hotel Las Américas

10/10 Excellent

"DELICIOSO EL DESAYUNO"

Novotel Santa Cruz De La Sierra

10/10 Excellent

"All around good price and location"

HOTEL OSHO

10/10 Excellent

"Good"

More cheap stays in Santa Cruz

Equipetrol Suites Apart Hotel

Equipetrol Santa Cruz Departamento de Santa Cruz

￥7,262

￥7,262 total

Sep 13 - Sep 14

Ibiza Hostel

445 Santa Cruz Departamento de Santa Cruz

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Amaca Hostal

249 Independencia Santa Cruz Departamento de Santa Cruz

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Casa Por Temporadas

Barrio Las Pampitas, calle 3 Nro. 99 Santa Cruz Santa Cruz Department

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10/10 Exceptional! (1 review)

HOTEL CASA BLANCA

Avenida Marcelo Terceros Zona Equipetrol Santa Cruz Santa Cruz de la Sierra

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Hotel Viru Viru II

Av. Alameda 72 - Zona Valle Sanchez Santa Cruz Santa Cruz de la Sierra

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4.8/10 (3 reviews)

Frequently asked questions

What's the best place for a stay in Santa Cruz?

Ibis Santa Cruz DE LA Sierra is one of the top choices for your stay based on our traveler data. This hotel offers a restaurant and free parking. Other good choices for your visit include Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel and Marriott Santa Cruz de la Sierra Hotel. See all available top hotels, or vacation rentals in Santa Cruz.

What's the top vacation rental that Santa Cruz has to offer?

Casa Vida: Visitors give good reviews to this Santa Cruz vacation home rental, which is located in a rural location and has an outdoor pool, a patio, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a full-sized fridge, a stovetop, and a microwave, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a private yard and a selection of games. Some other homes for rent in Santa Cruz include Cozy 1-bedroom house in beautiful Santa Cruz de la Sierra with WiFi, AC and Mi casa su casa, moderna y chic.. See all vacation rentals in Santa Cruz.

If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?

Yes! Most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.

Where can I learn more about changing or cancelling my trip to Santa Cruz?

To find more details about picking new dates or cancelling your trip to Santa Cruz, head over to our customer service page.

What's the best budget-friendly accommodation in Santa Cruz?

Based on our traveler reviews, residencial francia - Hostel is a top choice for a less expensive stay. Other choices for your budget-friendly stay include Ibiza Hostel and Residencial Ikandire II. View all budget hotels in Santa Cruz.

What's the best accommodation for a family trip to Santa Cruz?

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel is a hotel with 2 restaurants and free parking, and it's a top choice on Expedia for families. Other choices for your stay with the kids include Marriott Santa Cruz de la Sierra Hotel and Camino Real Hotel. Attractions like Santa Cruz Zoo and Play Land Amusement Park are also fun for kids of all ages. Find more child-friendly accommodations in Santa Cruz.

What is the top LGBTQ-friendly accommodation in Santa Cruz?

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is a top LGBTQ-friendly hotel that features free breakfast and free WiFi. Swissôtel Santa Cruz De La Sierra and Hotel Pascana centro are other good choices for your trip. See all available hotels listed as LGBTQ-friendly in Santa Cruz.

What's the best pet-friendly hotel in Santa Cruz?

Ibis Santa Cruz DE LA Sierra is a top hotel for people traveling with their pets, and offers a restaurant and free WiFi for its human guests. Other good options for you and your pet's trip include Casa Por Temporadas and Swissôtel Santa Cruz De La Sierra. See more pet-friendly hotel accommodations in Santa Cruz.

Where is the best place to stay close to Plaza 24 de Septiembre?

Adjacent to Plaza 24 de Septiembre, Nomad Hostel is one of the top choices for your stay based on our traveler data, and this property offers a restaurant and a bar. Other good options close by include Senses Centro and Cosmopolitano Hotel Boutique.

What about the best place to stay near Ventura Mall?

One of the top choices for your stay is Camino Real Hotel, located next to Ventura Mall, and this 4-star hotel offers 2 bars and a restaurant. Los Tajibos Hotel And Convention Center and Marriott Santa Cruz de la Sierra Hotel are two other good choices in the immediate area.

What's the best luxury accommodation in Santa Cruz?

Marriott Santa Cruz de la Sierra Hotel is a luxury hotel with a full-service spa and a rooftop terrace, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Camino Real Hotel and Hampton by Hilton Santa Cruz/Equipetrol, Bolivia are other upscale choices for your vacation. Find more luxury hotels in Santa Cruz.

What are some accommodations with pools in Santa Cruz?

Yotau All Suites Hotel is a top hotel with 2 outdoor pools, a children's pool, and 2 restaurants. A couple of other options that offer an onsite pool include Buganvillas Hotel Suites & Spa and Gran Hotel Santa Cruz. View all hotels with pools in Santa Cruz.

What is the best spa hotel in Santa Cruz?

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel is a top spa hotel featuring a fitness center, a hair salon, and a bar. Enjoy a facial, body scrub, or hydrotherapy at Los Tajibos Club Spa. Other popular spa hotels in Santa Cruz include Marriott Santa Cruz de la Sierra Hotel and Camino Real Hotel. See all spa hotels in Santa Cruz.

What's the top hotel in Santa Cruz with an on-site water park or a water park nearby?

Gran Hotel Santa Cruz is a popular hotel featuring free water park access, an outdoor pool, and a restaurant. Check out all hotels with or near waterparks in Santa Cruz.

What's the best hotel for staying near Viru Viru International Airport (VVI)?

Sun Hotel is a popular 3.5-star hotel featuring free breakfast and a restaurant. It's located a short 1.3 mi (2.1 km) from Viru Viru Intl. Airport.

How is it to stay in Santa Cruz?

Visitors to Santa Cruz are sure to enjoy the shopping. Tourists can also enjoy the city's cafes, zoo, and cathedral. In Santa Cruz, there are 311 hotels and other accommodations to choose from. Find out more about Santa Cruz.

What should I do while I'm visiting Santa Cruz?

Cultural venues include Ethno-folkloric Museum, Cine Center, and Sacred Art Museum. Landmarks like San Lorenzo Cathedral, Plaza 24 de Septiembre, and Blacutt Square might be worth a visit. Natural beauty is on display at Arenal Park, Guembe Biocenter, and Lomas de Arena Regional Park. Check out what more to see and do in Expedia's Santa Cruz guide.

How should I get around Santa Cruz?

To see more of the larger area, ride aboard one of the trains from Santa Cruz de la Sierra Station. If you want to venture out around the area, you may want a rental car in Santa Cruz for your journey.

What's the weather like in Santa Cruz?

The hottest months are usually October and November with an average temp of 79°F, while the coldest months are June and July with an average of 70°F. Average annual precipitation for Santa Cruz is 48 inches.

Find hotels in Santa Cruz from ￥3,774

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Santa Cruz

Check prices for these dates

Filter by

Property class

Guest rating

Our top choices for Santa Cruz hotels

1. Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

2. Ibis Santa Cruz DE LA Sierra

3. Marriott Santa Cruz de la Sierra Hotel

4. Camino Real Hotel

5. Hotel Cortez

6. Premium Suites Deluxe Aparthotel Equipetrol

7. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

8. Sun Hotel

9. Delfines Collection Hotel By Mercure

10. TRYP by Wyndham Santa Cruz

11. Chairú Eco Hotel

12. Novotel Santa Cruz De La Sierra

13. HOTEL OSHO

14. Hotel Las Américas

15. Lido Hotel

16. Alfonsina Hotel Boutique by Inboccaluppo

17. Hotel LP Equipetrol

18. Swissôtel Santa Cruz De La Sierra

19. Cosmopolitano Hotel Boutique

20. Hotel LP Santa Cruz Centro

Vacation Rentals in Santa Cruz

Premium Suites Deluxe Aparthotel Equipetrol

Apart Hotel Premium Suites Santa Cruz

AMERICA APARTMENTS

Terranova Suites

Equipetrol Suites Apart Hotel

Apart Hotel Toborochi

Casa Vida

Where to stay in Santa Cruz

Hamacas

Centro Histórico

Urubó

Zona Sur (South Zone)

Equipetrol

Stay near popular Santa Cruz attractions

Plaza 24 de Septiembre

San Lorenzo Cathedral

Ventura Mall

Guembe Biocenter

Santa Cruz Zoo

Ramon Tahuichi Aguilera Stadium

Blacutt Square

Cine Center

Learn more about Santa Cruz

Top Santa Cruz Hotel Reviews

Ibis Santa Cruz DE LA Sierra

Hotel Cortez

Sun Hotel

TRYP by Wyndham Santa Cruz

Camino Real Hotel

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hotel Las Américas

Novotel Santa Cruz De La Sierra

HOTEL OSHO

More cheap stays in Santa Cruz

Equipetrol Suites Apart Hotel

Ibiza Hostel

Amaca Hostal

Casa Por Temporadas

HOTEL CASA BLANCA

Hotel Viru Viru II

Frequently asked questions

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