Top 10 Hotels in Santa Cruz from ￥3,761 - Competitive Prices

A colonial-style building with a bell tower, palm trees, and a paved walkway.

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Our top choices for Santa Cruz hotels

A poolside area with lounge chairs and a palm tree.

A banquet hall with long tables, chandeliers, and draped curtains.

A dining table with breakfast items and a pool view.

A modern hotel entrance with a curved canopy, large columns, and a well-lit facade.

1. Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Santa Cruz

ERNESTO

￥20,109

￥20,109 total

Oct 4 - Oct 5

A modern lobby with seating areas, a coffee table, and a large potted plant.

A modern hotel with multiple floors, large windows, and a prominent red sign on the facade.

A modern shower with a glass door, tiled walls, and a visible toilet in the adjacent bathroom.

2. Ibis Santa Cruz DE LA Sierra

Santa Cruz

Hui Hua

￥5,659

￥5,659 total

Oct 1 - Oct 2

A modern hotel with a rooftop pool featuring illuminated blue and purple lights, lounge chairs, and a palm tree.

A modern lobby with a dining area, sofas, and a decorative wall.

A modern lobby with a curved staircase, seating area, and a large wooden bookshelf.

A luxurious banquet hall with ornate chandeliers, floral arrangements, and elegant table settings.

3. Marriott Santa Cruz de la Sierra Hotel

Santa Cruz

Deivis

￥16,796

￥16,796 total

Oct 2 - Oct 3

A spacious lobby with high ceilings, modern furniture, and large windows allowing natural light.

A large, illuminated swimming pool surrounded by palm trees and pathways.

A restaurant with a long counter, dark chairs, and hanging lights.

A hot tub with a wooden deck and stone walls, surrounded by a pool.

4. Camino Real Hotel

Santa Cruz

Austin

￥21,695

￥21,695 total

Oct 4 - Oct 5

A swimming pool with a water slide, surrounded by a hotel building with multiple floors and outdoor seating areas.

A spacious lobby with high ceilings, wooden beams, and a large seating area with wicker chairs.

A buffet with various fruits and snacks.

5. Hotel Cortez

Santa Cruz

Leonora

￥19,204

￥19,204 total

Oct 4 - Oct 5

A rooftop pool with a water feature, surrounded by modern buildings and a clear sky.

A buffet setup with various food items, including pastries, a cake, and beverages.

A modern staircase with glass railings, leading to a landing with a small garden area.

A hotel room with a large bed, a TV mounted on the wall, a dining area with chairs, and a sofa.

6. Premium Suites Deluxe Aparthotel Equipetrol

Santa Cruz

Luisa

￥7,304

￥7,304 total

Sep 7 - Sep 8

A modern restaurant with a city view, featuring glass tables, white chairs, and a large window with curtains.

A modern hotel lobby with a bar area, seating arrangements, and a television.

A small, enclosed garden area with various potted plants and a gravel path.

A hotel room with a large bed, a desk, a chair, a telephone, and a view of the city through large windows.

7. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Santa Cruz

imilse de

￥11,686

￥11,686 total

Oct 2 - Oct 3

A hotel with a large swimming pool, multiple balconies, and a central arched entrance.

A table set for a meal with a view of a body of water and decorative lighting.

A hotel room with two beds, a large window with a view of a pool, and a desk with a chair.

A spacious indoor area with multiple dining tables and chairs, a staircase, and large windows offering a view of the outdoors.

8. Sun Hotel

Santa Cruz

Daniela

￥17,277

￥17,277 total

Oct 4 - Oct 5

A rooftop pool with a glass barrier reflecting the sunset and city skyline.

An outdoor dining area with tables and chairs, a wooden pergola with hanging lights, and a city view.

A buffet with various food items and a pitcher of orange juice.

A hotel room with two beds, a desk, and a view of the city.

9. Delfines Collection Hotel By Mercure

Santa Cruz

Mathetes

￥7,693

￥7,693 total

Sep 7 - Sep 8

A modern building with the sign "TRYP SANTA CRUZ" and a glass entrance with decorative lighting.

A rooftop pool area with a view of the city skyline at dusk.

A reception area with a marble counter, a large chandelier, and a digital display.

A modern hotel room with a cityscape view at sunset, a tufted headboard, and a neatly made bed with white linens and dark accents.

10. TRYP by Wyndham Santa Cruz

Santa Cruz

Pluetina

￥17,307

￥17,307 total

Sep 4 - Sep 5

The exterior of the ECO HOTEL with illuminated signage and a wooden canopy.

A room with a large window, a brick wall, and a hanging plant.

A multi-level atrium with a central planter containing various plants, surrounded by glass railings and a brick wall.

A rooftop terrace with a view of the city skyline, including modern buildings and construction cranes.

11. Chairú Eco Hotel

Santa Cruz

Shabbir

￥8,652

￥8,652 total

Oct 4 - Oct 5

A spacious hotel lobby with modern furnishings, large windows offering city views, and unique hanging light fixtures.

A spacious lobby with a high ceiling, modern furniture, and a central seating area.

A window seat with a view of a cityscape at dusk.

A nighttime pool area with a blue-lit water surface, palm trees, and a modern building with geometric light patterns in the background.

12. Novotel Santa Cruz De La Sierra

Santa Cruz

ERNESTO

￥19,625

￥19,625 total

Oct 1 - Oct 2

A modern hotel room with a large bed, bedside tables, a desk with a chair, a small fridge, and a TV mounted on the wall.

A modern hotel lobby with a curved ceiling, a reception desk, and two artworks on the walls.

A hotel room with two beds, a sofa, a TV, and a wall-mounted light fixture.

13. HOTEL OSHO

Santa Cruz

David

￥7,577

￥9,959 total

Sep 5 - Sep 6

A balcony with a table set for breakfast, including a plate of fruit, a glass of orange juice, and a cup. The view includes a cityscape with buildings and a clear sky.

A hotel with a unique wavy facade, multiple parking spaces, and a clear blue sky.

A buffet setup with various food items and a serving area.

14. Hotel Las Américas

Santa Cruz

Stanley

￥4,144

￥4,144 total

Sep 5 - Sep 6

A spacious living area with a high ceiling, wooden beams, a staircase, and a view of a balcony.

Wicker furniture with cushions, potted plants, and a ceiling with lights.

A traditional-style room with a sofa set, a table, and two chairs.

A staircase with ornate lion statues at the base, a chandelier, and a framed artwork on the wall.

15. Lido Hotel

Santa Cruz

Gabrielle

￥3,761

￥3,761 total

Sep 14 - Sep 15

A building entrance with steps leading up to a glass door, a plaque reading "Coco Kl Primer B", and a sign for "Inmobili Calupo".

A staircase with a metal railing, wooden steps, and a concrete wall with framed pictures.

A modern outdoor pool area with a red brick wall, a large mural, and outdoor furniture.

A long bar with a wooden countertop, shelves with glassware, and framed pictures on the wall.

16. Alfonsina Hotel Boutique by Inboccaluppo

Santa Cruz

Elizabeth

￥17,117

￥17,117 total

Sep 24 - Sep 25

A buffet setup with various food items and beverages.

A corridor with wooden doors, orange walls, and a carpeted floor.

A tall hotel with a prominent 'LP' sign, featuring a modern design with large windows and a flat facade.

A modern hotel room with a large bed, a desk, a chair, and a view of the outside.

17. Hotel LP Equipetrol

Santa Cruz

Ricardo

￥5,790

￥6,591 total

Sep 5 - Sep 6

A spacious room with a wooden floor and large windows offering a city view.

A modern interior with a large mural of traditional figures, a glass railing, and contemporary lighting fixtures.

A hotel room with two beds, a nightstand, and a wall-mounted lamp.

A buffet table with various food items and a wine bottle.

18. Swissôtel Santa Cruz De La Sierra

Santa Cruz

GONZALO

￥26,040

￥26,040 total

Sep 17 - Sep 18

A modern hotel room with a large bed, a bedside table with a lamp, a small bench, and a glass-enclosed bathroom.

A multi-level indoor space with a pool, wooden flooring, and potted plants.

A building with a sign that reads "COSMOPOLITANO."

A room with a bed, a small wooden stool, a potted plant in a black frame, and a door in the background.

19. Cosmopolitano Hotel Boutique

Santa Cruz

Veronica

￥8,888

￥8,888 total

Sep 28 - Sep 29

A hotel room with a large window, a desk with a chair, a bed with white bedding and a blue accent, and a TV mounted on the wall.

A modern lobby with a glass wall, a blue sofa, a glass table, and a patterned ottoman.

A modern reception area with a grey reception desk labeled "hola. bienvenido".

A hotel entrance with glass doors, a sign reading "LP HOTELES", and a green wall.

20. Hotel LP Santa Cruz Centro

Santa Cruz

John

￥5,951

￥6,745 total

Oct 4 - Oct 5

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Vacation Rentals in Santa Cruz

Aparthotel

Premium Suites Deluxe Aparthotel Equipetrol

Santa Cruz

"great place to stay!"

Aparthotel

An outdoor dining area with tables and chairs, surrounded by plants and palm trees.

A hotel room with a bed, a sofa, a coffee table, and a vase of flowers.

A modern hotel with a swimming pool, lounge chairs, and a clear sky.

A kitchen with granite countertops, wooden chairs, a microwave, and a window.

Terranova Suites

Santa Cruz

"Easy to access"

Apartment

A hotel sign with the text "Apart Hotel Premium Suites Santa Cruz".

A balcony with two wooden chairs and a table, overlooking a cityscape with various buildings.

A reception desk with a wooden panel wall behind it, displaying the text "Premium Suites".

A group of women standing in a modern interior with wooden paneling and a reception desk.

Apart Hotel Premium Suites Santa Cruz

Santa Cruz

"Great location."

Apartment

A modern rooftop pool with a city view, wooden flooring, and a seating area.

A modern hotel room with a bed, bedside table, and a desk with a chair.

A modern living room with a sofa and a kitchen area featuring a microwave, kettle, and a coffee machine.

A modern kitchen with a built-in grill, a black countertop, and a wall mural of tropical leaves.

AMERICA APARTMENTS

Santa Cruz

"Clean room, great staff "

Aparthotel

A hotel with multiple floors, a pool area with lounge chairs, and palm trees.

A tropical garden with a wooden deck, a hot tub, and lush greenery.

A spacious lobby with a central round table, seating area, and a reception desk.

A modern dining area with a glass table and striped chairs, a white tablecloth, and a view of a kitchen and bar area.

Apart Hotel Toborochi

Santa Cruz

"Very comfortable and quiet place and very good location. "

Aparthotel

A modern hotel room with a bed, a nightstand, a lamp, a painting, a kitchen area, and a bathroom.

A cozy seating area with a round wooden table, a white cup, and a book.

A hotel reception area with a reception desk, a waiting area with a chair and ottoman, and an elevator.

A compact kitchen with a stove, sink, and coffee maker. A bed with a blue pillow is visible in the background.

Equipetrol Suites Apart Hotel

Santa Cruz

"Perfect hotel"

Vacation Home

A swimming pool with a waterfall feature, surrounded by lush greenery and palm trees.

Casa Vida

Santa Cruz

"buena recepción, el lugar es muy bueno un poco alejado de la ciudad, falta comodidad en algunos aspectos pero la casa es grande y espaciosa"

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Where to stay in Santa Cruz

Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most.Learn more about Santa Cruz

Hamacas

Hamacas

While Hamacas isn't home to many top sights, Santa Cruz Zoo and Las Brisas Shopping Center are some notable places to visit nearby.

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Stay near popular Santa Cruz attractions

A historic building with arched windows and a clock. People are sitting and standing on the steps in front of the building.

Plaza 24 de Septiembre

8.8/10 (164 reviews)

Plaza 24 de Septiembre buzzes with local culture beneath swaying palms and colonial architecture. Climb the Cathedral's bell tower for spectacular city views while sampling authentic Bolivian coffee from vendors.

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An interior of a church with high arched ceilings, wooden pews, and a central altar.

San Lorenzo Cathedral

9.0/10 (84 reviews)

This grand neoclassical cathedral dominates Santa Cruz's skyline with its towering spires and ornate façade. Climb the bell tower at sunset for breathtaking panoramic views of the city.

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Ventura Mall

9.0/10 (183 reviews)

Ventura Mall, Santa Cruz's premier shopping destination, features international brands and local boutiques. Enjoy the cinema complex, food court, and entertainment options in this contemporary Bolivian retail hub.

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Guembe Biocenter

8.8/10 (60 reviews)

This vibrant ecological sanctuary showcases hundreds of butterfly species in a lush, tropical environment. Explore walking trails, enjoy boat rides, and learn about biodiversity in this serene natural retreat.

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Santa Cruz Zoo

8.4/10 (53 reviews)

The Santa Cruz Municipal Zoo showcases Bolivia's native wildlife in naturalistic habitats, featuring jaguars, tapirs, and free-ranging sloths. Morning visits offer the best chance to see active animals.

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Cine Center

8.0/10 (53 reviews)

This premier entertainment complex offers state-of-the-art cinema experiences with immersive 4D E-Motion formats. Enjoy the latest films, then explore the shopping center and diverse dining options in the food court.

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Ramon Tahuichi Aguilera Stadium

8.4/10 (18 reviews)

This multi-purpose stadium hosts Bolivia's most passionate football rivalries and tournaments. Experience the electric atmosphere of a local derby while enjoying modernized facilities and vibrant Santa Cruz culture.

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Las Brisas Shopping Center

8.4/10 (40 reviews)

This modern complex offers 80+ stores, a nine-screen cinema, and a unique outdoor restaurant promenade. Explore the gastronomic boulevard for dining experiences beyond the standard food court options.

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Learn more about Santa Cruz

Tropical energy pulses through Plaza 24 de Septiembre, where locals gather under palm trees and the Metropolitan Cathedral's twin towers stand watch. Biocentro Güembé offers rainforest trails with butterfly gardens, while the massive Ventura Mall provides air-conditioned shopping when afternoon temperatures climb.

See all hotels in Santa Cruz

Top Santa Cruz Hotel Reviews

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

10/10 Excellent

"Breakfast is wonderful"

Ibis Santa Cruz DE LA Sierra

10/10 Excellent

"La ubicación es muy buena y puedes caminar por la zona"

Novotel Santa Cruz De La Sierra

10/10 Excellent

"All around good price and location"

Marriott Santa Cruz de la Sierra Hotel

10/10 Excellent

"Staff was super as well as how clean the room was."

HOTEL OSHO

10/10 Excellent

"Good"

Delfines Collection Hotel By Mercure

10/10 Excellent

"Todo muy bien"

Hotel LP Equipetrol

8/10 Good

"El cuarto agradable, pero faltó servicio de ayuda para subir y bajar maletas, también servicio adecuado de taxi para moverse en Santa Cruz"

Apart Hotel Premium Suites Santa Cruz

10/10 Excellent

"Great location."

More cheap stays in Santa Cruz

Equipetrol Suites Apart Hotel

Equipetrol Santa Cruz Departamento de Santa Cruz

￥7,303

￥7,303 total

Sep 25 - Sep 26

Ibiza Hostel

445 Santa Cruz Departamento de Santa Cruz

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Amaca Hostal

249 Independencia Santa Cruz Departamento de Santa Cruz

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Casa Por Temporadas

Barrio Las Pampitas, calle 3 Nro. 99 Santa Cruz Santa Cruz Department

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10/10 Exceptional! (1 review)

HOTEL CASA BLANCA

Avenida Marcelo Terceros Zona Equipetrol Santa Cruz Santa Cruz de la Sierra

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Hotel Viru Viru II

Av. Alameda 72 - Zona Valle Sanchez Santa Cruz Santa Cruz de la Sierra

Get rates

4.8/10 (3 reviews)

Frequently asked questions

What's the best place for a stay in Santa Cruz?

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel is one of the top choices for your stay based on our traveler data. This hotel offers a full-service spa and 2 restaurants. Other good choices for your visit include Ibis Santa Cruz DE LA Sierra and Marriott Santa Cruz de la Sierra Hotel. See all available top hotels, or vacation rentals in Santa Cruz.

What's the top vacation rental that Santa Cruz has to offer?

Casa Vida: Visitors give good reviews to this Santa Cruz vacation home rental, which is located in a rural location and has an outdoor pool, a patio, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a full-sized fridge, a stovetop, and a microwave, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a private yard and a selection of games. Some other homes for rent in Santa Cruz include Cozy 1-bedroom house in beautiful Santa Cruz de la Sierra with WiFi, AC and Seasonal House. See all vacation rentals in Santa Cruz.

If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?

Yes! Most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.

Where can I learn more about changing or cancelling my trip to Santa Cruz?

To find more details about picking new dates or cancelling your trip to Santa Cruz, head over to our customer service page.

What's the best budget-friendly accommodation in Santa Cruz?

Based on our traveler reviews, Ibiza Hostel is a top choice for a less expensive stay. Other choices for your budget-friendly stay include residencial francia - Hostel and Residencial Ikandire II. View all budget hotels in Santa Cruz.

What's the best accommodation for a family trip to Santa Cruz?

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel is a hotel with 2 restaurants and free parking, and it's a top choice on Expedia for families. Other choices for your stay with the kids include Marriott Santa Cruz de la Sierra Hotel and Camino Real Hotel. Attractions like Santa Cruz Zoo and Play Land Amusement Park are also fun for kids of all ages. Find more child-friendly accommodations in Santa Cruz.

What is the top LGBTQ-friendly accommodation in Santa Cruz?

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is a top LGBTQ-friendly hotel that features free breakfast and free WiFi. Swissôtel Santa Cruz De La Sierra and Radisson Hotel Santa Cruz are other good choices for your trip. See all available hotels listed as LGBTQ-friendly in Santa Cruz.

What's the best pet-friendly hotel in Santa Cruz?

Casa Por Temporadas is a top dog-friendly guesthouse, and offers an outdoor pool along with in-room kitchens for its human guests. Other good options for you and your pet's trip include Ibis Santa Cruz DE LA Sierra and Swissôtel Santa Cruz De La Sierra. See more pet-friendly hotel accommodations in Santa Cruz.

Where is the best place to stay close to Plaza 24 de Septiembre?

Adjacent to Plaza 24 de Septiembre, Nomad Hostel is one of the top choices for your stay based on our traveler data, and this property offers a restaurant and a bar. Other good options close by include Senses Centro and Cosmopolitano Hotel Boutique.

What about the best place to stay near Ventura Mall?

One of the top choices for your stay is Camino Real Hotel, located next to Ventura Mall, and this 4-star hotel offers 2 bars and a restaurant. Los Tajibos Hotel And Convention Center and Marriott Santa Cruz de la Sierra Hotel are two other good choices in the immediate area.

What's the best luxury accommodation in Santa Cruz?

Marriott Santa Cruz de la Sierra Hotel is a luxury hotel with a full-service spa and a rooftop terrace, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Camino Real Hotel and Hampton by Hilton Santa Cruz/Equipetrol, Bolivia are other upscale choices for your vacation. Find more luxury hotels in Santa Cruz.

What are some accommodations with pools in Santa Cruz?

Yotau All Suites Hotel is a top hotel with 2 outdoor pools, a children's pool, and 2 restaurants. A couple of other options that offer an onsite pool include Buganvillas Hotel Suites & Spa and Loft sobrio, rooftop panorámico y piscina infinita. View all hotels with pools in Santa Cruz.

What is the best spa hotel in Santa Cruz?

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel is a top spa hotel featuring a fitness center, a hair salon, and a bar. Enjoy a facial, body scrub, or hydrotherapy at Los Tajibos Club Spa. Other popular spa hotels in Santa Cruz include Marriott Santa Cruz de la Sierra Hotel and Camino Real Hotel. See all spa hotels in Santa Cruz.

What's the best hotel for staying near Viru Viru International Airport (VVI)?

Sun Hotel is a popular 3.5-star hotel featuring free breakfast and a restaurant. It's located a short 1.3 mi (2.1 km) from Viru Viru Intl. Airport.

How is it to stay in Santa Cruz?

Visitors to Santa Cruz are sure to enjoy the shopping. Tourists can also enjoy the city's cafes, zoo, and cathedral. In Santa Cruz, there are 305 hotels and other accommodations to choose from. Find out more about Santa Cruz.

What should I do while I'm visiting Santa Cruz?

Cultural venues include Cine Center, Ethno-folkloric Museum, and Sacred Art Museum. Landmarks like San Lorenzo Cathedral, Plaza 24 de Septiembre, and Blacutt Square might be worth a visit. Natural beauty is on display at Guembe Biocenter, Lomas de Arena Regional Park, and Arenal Park. Check out what more to see and do in Expedia's Santa Cruz guide.

How should I get around Santa Cruz?

To see more of the larger area, ride aboard one of the trains from Santa Cruz de la Sierra Station. If you want to venture out around the area, you may want a rental car in Santa Cruz for your journey.

What's the weather like in Santa Cruz?

The hottest months are usually October and November with an average temp of 79°F, while the coldest months are June and July with an average of 70°F. Average annual precipitation for Santa Cruz is 48 inches.

Find hotels in Santa Cruz from ￥3,761

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Santa Cruz

Check prices for these dates

Filter by

Property class

Guest rating

Our top choices for Santa Cruz hotels

1. Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

2. Ibis Santa Cruz DE LA Sierra

3. Marriott Santa Cruz de la Sierra Hotel

4. Camino Real Hotel

5. Hotel Cortez

6. Premium Suites Deluxe Aparthotel Equipetrol

7. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

8. Sun Hotel

9. Delfines Collection Hotel By Mercure

10. TRYP by Wyndham Santa Cruz

11. Chairú Eco Hotel

12. Novotel Santa Cruz De La Sierra

13. HOTEL OSHO

14. Hotel Las Américas

15. Lido Hotel

16. Alfonsina Hotel Boutique by Inboccaluppo

17. Hotel LP Equipetrol

18. Swissôtel Santa Cruz De La Sierra

19. Cosmopolitano Hotel Boutique

20. Hotel LP Santa Cruz Centro

Vacation Rentals in Santa Cruz

Premium Suites Deluxe Aparthotel Equipetrol

Terranova Suites

Apart Hotel Premium Suites Santa Cruz

AMERICA APARTMENTS

Apart Hotel Toborochi

Equipetrol Suites Apart Hotel

Casa Vida

Where to stay in Santa Cruz

Hamacas

Stay near popular Santa Cruz attractions

Plaza 24 de Septiembre

San Lorenzo Cathedral

Ventura Mall

Guembe Biocenter

Santa Cruz Zoo

Cine Center

Ramon Tahuichi Aguilera Stadium

Las Brisas Shopping Center

Learn more about Santa Cruz

Top Santa Cruz Hotel Reviews

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Ibis Santa Cruz DE LA Sierra

Novotel Santa Cruz De La Sierra

Marriott Santa Cruz de la Sierra Hotel

HOTEL OSHO

Delfines Collection Hotel By Mercure

Hotel LP Equipetrol

Apart Hotel Premium Suites Santa Cruz

More cheap stays in Santa Cruz

Equipetrol Suites Apart Hotel

Ibiza Hostel

Amaca Hostal

Casa Por Temporadas

HOTEL CASA BLANCA

Hotel Viru Viru II

Frequently asked questions

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