Top 10 Hotels in Santa Cruz from ￥3,292 - Competitive Prices

A colonial-style building with a bell tower, palm trees, and a paved walkway.

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Condo

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Our top choices for Santa Cruz hotels

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Plaza 24 de Septiembre

Hotel

1. Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Santa Cruz

Andrew

￥19,980

￥19,980 total

Aug 16 - Aug 17

2. Ibis Santa Cruz DE LA Sierra

Santa Cruz

Sarinela

￥5,367

￥5,367 total

Aug 24 - Aug 25

Outdoor pool, pool umbrellas, sun loungers

3. Marriott Santa Cruz de la Sierra Hotel

Santa Cruz

Deivis

￥16,688

￥16,688 total

Aug 14 - Aug 15

Indoor pool, outdoor pool, pool umbrellas

4. Camino Real Hotel

Santa Cruz

Austin

￥19,685

￥19,685 total

Sep 9 - Sep 10

5. Hotel Cortez

Santa Cruz

Sarinela

￥18,288

￥18,288 total

Sep 9 - Sep 10

Outdoor pool, open 9:00 AM to 8:00 PM, sun loungers

6. Premium Suites Deluxe Aparthotel Equipetrol

Santa Cruz

Luisa

￥5,557

￥6,280 total

Aug 23 - Aug 24

7. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Santa Cruz

imilse de

￥11,611

￥11,611 total

Aug 15 - Aug 16

Premium Suite, 2 Queen Beds, Pool View | View from room

8. Sun Hotel

Santa Cruz

JACK

￥17,038

￥17,038 total

Aug 10 - Aug 11

9. Delfines Collection Hotel By Mercure

Santa Cruz

ALEJANDRO

￥7,525

￥7,525 total

Aug 23 - Aug 24

Down comforters, minibar, in-room safe, blackout drapes

10. TRYP by Wyndham Santa Cruz

Santa Cruz

Pluetina

￥15,476

￥15,476 total

Aug 10 - Aug 11

11. Chairú Eco Hotel

Santa Cruz

marcia

￥8,519

￥8,519 total

Aug 10 - Aug 11

Outdoor pool, open 8:00 AM to 11:00 PM, free cabanas, pool umbrellas

12. Novotel Santa Cruz De La Sierra

Santa Cruz

ERNESTO

￥19,499

￥19,499 total

Sep 1 - Sep 2

Honeymoon Room, 1 King Bed | Egyptian cotton sheets, premium bedding, pillowtop beds, minibar

Comfort Double Room, 2 Queen Beds, Ensuite, City View | Egyptian cotton sheets, premium bedding, pillowtop beds, minibar

13. HOTEL OSHO

Santa Cruz

David

￥6,777

￥9,143 total

Aug 11 - Aug 12

Triple Room | Down comforters, WiFi (free), bed sheets

14. Hotel Las Américas

Santa Cruz

Stanley

￥5,457

￥5,457 total

Aug 10 - Aug 11

15. Lido Hotel

Santa Cruz

Gabrielle

￥5,700

￥5,700 total

Aug 10 - Aug 11

16. Alfonsina Hotel Boutique by Inboccaluppo

Santa Cruz

Elizabeth

￥17,006

￥17,006 total

Aug 12 - Aug 13

17. Hotel LP Equipetrol

Santa Cruz

Ricardo

￥6,231

￥7,020 total

Aug 30 - Aug 31

18. Swissôtel Santa Cruz De La Sierra

Santa Cruz

GONZALO

￥23,348

￥23,348 total

Aug 24 - Aug 25

Premium Room, 1 Queen Bed, Bathtub | Minibar, in-room safe, desk, soundproofing

City Loft, 1 Double Bed, Courtyard Area | Minibar, in-room safe, desk, soundproofing

19. Cosmopolitano Hotel Boutique

Santa Cruz

Heidi

￥8,755

￥8,755 total

Aug 16 - Aug 17

Standard Room, 2 Twin Beds | Premium bedding, minibar, in-room safe, desk

20. Hotel LP Santa Cruz Centro

Santa Cruz

John

￥7,685

￥8,474 total

Sep 9 - Sep 10

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Vacation Rentals in Santa Cruz

Aparthotel

Premium Suites Deluxe Aparthotel Equipetrol

Santa Cruz

"great place to stay!"

Apartment

1 bedroom, in-room safe, desk, iron/ironing board (on request)

Business Apartment, 2 Bedrooms (Plus) | In-room dining

Apart Hotel Premium Suites Santa Cruz

Santa Cruz

"Great location."

Aparthotel

Premium Room | Living area | 32-inch flat-screen TV with cable channels

Terranova Suites

Santa Cruz

"Easy to access"

Aparthotel

Standard Suite, 1 Queen Bed | Hypo-allergenic bedding available, down comforters, desk

Standard Suite, 1 Queen Bed | Private kitchen | Mini-fridge, microwave, dishwasher, toaster

Junior Suite, 1 Queen Bed | Hypo-allergenic bedding available, down comforters, desk

Equipetrol Suites Apart Hotel

Santa Cruz

"Perfect hotel"

Apartment

Classic Apartment, City View | Desk, blackout drapes, iron/ironing board (on request), WiFi (free)

AMERICA APARTMENTS

Santa Cruz

"Clean room, great staff "

Aparthotel

Apart Hotel Toborochi

Santa Cruz

"Very comfortable and quiet place and very good location. "

Vacation Home

House | Pool | Outdoor pool, pool umbrellas, sun loungers

Casa Vida

Santa Cruz

"buena recepción, el lugar es muy bueno un poco alejado de la ciudad, falta comodidad en algunos aspectos pero la casa es grande y espaciosa"

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Where to stay in Santa Cruz

Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most.Learn more about Santa Cruz

Hamacas

Hamacas

While Hamacas isn't home to many top sights, Santa Cruz Zoo and Las Brisas Shopping Center are some notable places to visit nearby.

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Stay near popular Santa Cruz attractions

A historic building with arched windows and a clock. People are sitting and standing on the steps in front of the building.

Plaza 24 de Septiembre

8.8/10 (164 reviews)

Plaza 24 de Septiembre buzzes with local culture beneath swaying palms and colonial architecture. Climb the Cathedral's bell tower for spectacular city views while sampling authentic Bolivian coffee from vendors.

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An interior of a church with high arched ceilings, wooden pews, and a central altar.

San Lorenzo Cathedral

9.0/10 (84 reviews)

This grand neoclassical cathedral dominates Santa Cruz's skyline with its towering spires and ornate façade. Climb the bell tower at sunset for breathtaking panoramic views of the city.

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Ventura Mall

9.0/10 (183 reviews)

Ventura Mall, Santa Cruz's premier shopping destination, features international brands and local boutiques. Enjoy the cinema complex, food court, and entertainment options in this contemporary Bolivian retail hub.

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Guembe Biocenter

8.8/10 (60 reviews)

This vibrant ecological sanctuary showcases hundreds of butterfly species in a lush, tropical environment. Explore walking trails, enjoy boat rides, and learn about biodiversity in this serene natural retreat.

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Santa Cruz Zoo

8.4/10 (53 reviews)

The Santa Cruz Municipal Zoo showcases Bolivia's native wildlife in naturalistic habitats, featuring jaguars, tapirs, and free-ranging sloths. Morning visits offer the best chance to see active animals.

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Cine Center

8.0/10 (53 reviews)

This premier entertainment complex offers state-of-the-art cinema experiences with immersive 4D E-Motion formats. Enjoy the latest films, then explore the shopping center and diverse dining options in the food court.

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Ramon Tahuichi Aguilera Stadium

8.4/10 (18 reviews)

This multi-purpose stadium hosts Bolivia's most passionate football rivalries and tournaments. Experience the electric atmosphere of a local derby while enjoying modernized facilities and vibrant Santa Cruz culture.

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Lomas de Arena Regional Park

8.4/10 (28 reviews)

Explore surreal desert-like sand dunes nestled within Bolivia's tropical landscape at Lomas de Arena. Sandboard down towering peaks or spot sloths and capybaras while hiking through diverse ecosystems.

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Learn more about Santa Cruz

Tropical energy pulses through Plaza 24 de Septiembre, where locals gather under palm trees and the Metropolitan Cathedral's twin towers stand watch. Biocentro Güembé offers rainforest trails with butterfly gardens, while the massive Ventura Mall provides air-conditioned shopping when afternoon temperatures climb.

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Top Santa Cruz Hotel Reviews

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

10/10 Excellent

"Como siempre el Mejor nivel para estancias en Santa Cruz"

Sun Hotel

10/10 Excellent

"El mejor servicio cerca del aeropuerto de Viru Viru"

Marriott Santa Cruz de la Sierra Hotel

10/10 Excellent

"Everything was great. Came for a business trip and would stay here again."

Premium Suites Deluxe Aparthotel Equipetrol

10/10 Excellent

"great place to stay!"

Camino Real Hotel

10/10 Excellent

"Enjoyed our stay. Warm welcome from the staff and great service. Highly recommended"

Ibis Santa Cruz DE LA Sierra

10/10 Excellent

"Great deal"

Hotel Cortez

10/10 Excellent

"Very good."

Hotel LP Equipetrol

8/10 Good

"El cuarto agradable, pero faltó servicio de ayuda para subir y bajar maletas, también servicio adecuado de taxi para moverse en Santa Cruz"

Alfonsina Hotel Boutique by Inboccaluppo

10/10 Excellent

"Good hotel. Very contemporary; buffet breakfast included. We walked to the old part of the city/cathedral - probably about 40 minutes walk but can stop for a coffee along the way! Restaurant and bar in hotel. Hotel also close to many other restaurants/bars"

More cheap stays in Santa Cruz

Ibiza Hostel

445 Santa Cruz Departamento de Santa Cruz

￥1,988

￥4,197 total

Aug 10 - Aug 11

Equipetrol Suites Apart Hotel

Equipetrol Santa Cruz Departamento de Santa Cruz

￥7,590

￥7,590 total

Aug 10 - Aug 11

Amaca Hostal

249 Independencia Santa Cruz Departamento de Santa Cruz

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Casa Por Temporadas

Barrio Las Pampitas, calle 3 Nro. 99 Santa Cruz Santa Cruz Department

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10/10 Exceptional! (1 review)

HOTEL CASA BLANCA

Avenida Marcelo Terceros Zona Equipetrol Santa Cruz Santa Cruz de la Sierra

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Hotel Viru Viru II

Av. Alameda 72 - Zona Valle Sanchez Santa Cruz Santa Cruz de la Sierra

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4.8/10 (3 reviews)

Frequently asked questions

What's the best place for a stay in Santa Cruz?

Ibis Santa Cruz DE LA Sierra is one of the top choices for your stay based on our traveler data. This hotel offers a restaurant and free parking. Other good choices for your visit include Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel and Marriott Santa Cruz de la Sierra Hotel. See all available top hotels, or vacation rentals in Santa Cruz.

What's the top vacation rental that Santa Cruz has to offer?

Casa Vida: Visitors give good reviews to this Santa Cruz vacation home rental, which is located in a rural location and has an outdoor pool, a patio, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a full-sized fridge, a stovetop, and a microwave, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a private yard and a selection of games. Some other homes for rent in Santa Cruz include Cozy 1-bedroom house in beautiful Santa Cruz de la Sierra with WiFi, AC and Seasonal House. See all vacation rentals in Santa Cruz.

If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?

Yes! Most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.

Where can I learn more about changing or cancelling my trip to Santa Cruz?

To find more details about picking new dates or cancelling your trip to Santa Cruz, head over to our customer service page.

What's the best budget-friendly accommodation in Santa Cruz?

Based on our traveler reviews, Ibiza Hostel is a top choice for a less expensive stay. Other choices for your budget-friendly stay include residencial francia - Hostel and Residencial Ikandire II. View all budget hotels in Santa Cruz.

What's the best accommodation for a family trip to Santa Cruz?

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel is a hotel with 2 restaurants and free parking, and it's a top choice on Expedia for families. Other choices for your stay with the kids include Marriott Santa Cruz de la Sierra Hotel and Camino Real Hotel. Attractions like Santa Cruz Zoo and Play Land Amusement Park are also fun for kids of all ages. Find more child-friendly accommodations in Santa Cruz.

What is the top LGBTQ-friendly accommodation in Santa Cruz?

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is a top LGBTQ-friendly hotel that features free breakfast and free WiFi. Swissôtel Santa Cruz De La Sierra and Radisson Hotel Santa Cruz are other good choices for your trip. See all available hotels listed as LGBTQ-friendly in Santa Cruz.

What's the best pet-friendly hotel in Santa Cruz?

Casa Por Temporadas is a top dog-friendly guesthouse, and offers an outdoor pool along with in-room kitchens for its human guests. Other good options for you and your pet's trip include Ibis Santa Cruz DE LA Sierra and Swissôtel Santa Cruz De La Sierra. See more pet-friendly hotel accommodations in Santa Cruz.

Where is the best place to stay close to Plaza 24 de Septiembre?

Adjacent to Plaza 24 de Septiembre, Nomad Hostel is one of the top choices for your stay based on our traveler data, and this property offers a restaurant and a bar. Other good options close by include Senses Centro and Cosmopolitano Hotel Boutique.

What about the best place to stay near Ventura Mall?

One of the top choices for your stay is Camino Real Hotel, located next to Ventura Mall, and this 4-star hotel offers 2 bars and a restaurant. Los Tajibos Hotel And Convention Center and Marriott Santa Cruz de la Sierra Hotel are two other good choices in the immediate area.

What's the best luxury accommodation in Santa Cruz?

Marriott Santa Cruz de la Sierra Hotel is a luxury hotel with a full-service spa and a rooftop terrace, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Camino Real Hotel and Novotel Santa Cruz De La Sierra are other upscale choices for your vacation. Find more luxury hotels in Santa Cruz.

What are some accommodations with pools in Santa Cruz?

Yotau All Suites Hotel is a top hotel with 2 outdoor pools, a children's pool, and 2 restaurants. A couple of other options that offer an onsite pool include Buganvillas Hotel Suites & Spa and Royal Lodge Hotel. View all hotels with pools in Santa Cruz.

What is the best spa hotel in Santa Cruz?

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel is a top spa hotel featuring a fitness center, a hair salon, and a bar. Enjoy a facial, body scrub, or hydrotherapy at Los Tajibos Club Spa. Other popular spa hotels in Santa Cruz include Marriott Santa Cruz de la Sierra Hotel and Camino Real Hotel. See all spa hotels in Santa Cruz.

What's the best hotel for staying near Viru Viru International Airport (VVI)?

Sun Hotel is a popular 3.5-star hotel featuring free breakfast and a restaurant. It's located a short 1.3 mi (2.1 km) from Viru Viru Intl. Airport.

How is it to stay in Santa Cruz?

Visitors to Santa Cruz are sure to enjoy the shopping. Tourists can also enjoy the city's cafes, zoo, and cathedral. In Santa Cruz, there are 298 hotels and other accommodations to choose from. Find out more about Santa Cruz.

What should I do while I'm visiting Santa Cruz?

Cultural venues include Cine Center, Ethno-folkloric Museum, and Sacred Art Museum. Landmarks like San Lorenzo Cathedral, Plaza 24 de Septiembre, and Blacutt Square might be worth a visit. Natural beauty is on display at Guembe Biocenter, Lomas de Arena Regional Park, and Arenal Park. Check out what more to see and do in Expedia's Santa Cruz guide.

How should I get around Santa Cruz?

To see more of the larger area, ride aboard one of the trains from Santa Cruz de la Sierra Station. If you want to venture out around the area, you may want a rental car in Santa Cruz for your journey.

What's the weather like in Santa Cruz?

The hottest months are usually October and November with an average temp of 79°F, while the coldest months are June and July with an average of 70°F. Average annual precipitation for Santa Cruz is 48 inches.

Find hotels in Santa Cruz from ￥3,292

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Santa Cruz

Check prices for these dates

Filter by

Property class

Guest rating

Our top choices for Santa Cruz hotels

1. Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

2. Ibis Santa Cruz DE LA Sierra

3. Marriott Santa Cruz de la Sierra Hotel

4. Camino Real Hotel

5. Hotel Cortez

6. Premium Suites Deluxe Aparthotel Equipetrol

7. Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

8. Sun Hotel

9. Delfines Collection Hotel By Mercure

10. TRYP by Wyndham Santa Cruz

11. Chairú Eco Hotel

12. Novotel Santa Cruz De La Sierra

13. HOTEL OSHO

14. Hotel Las Américas

15. Lido Hotel

16. Alfonsina Hotel Boutique by Inboccaluppo

17. Hotel LP Equipetrol

18. Swissôtel Santa Cruz De La Sierra

19. Cosmopolitano Hotel Boutique

20. Hotel LP Santa Cruz Centro

Vacation Rentals in Santa Cruz

Premium Suites Deluxe Aparthotel Equipetrol

Apart Hotel Premium Suites Santa Cruz

Terranova Suites

Equipetrol Suites Apart Hotel

AMERICA APARTMENTS

Apart Hotel Toborochi

Casa Vida

Where to stay in Santa Cruz

Hamacas

Stay near popular Santa Cruz attractions

Plaza 24 de Septiembre

San Lorenzo Cathedral

Ventura Mall

Guembe Biocenter

Santa Cruz Zoo

Cine Center

Ramon Tahuichi Aguilera Stadium

Lomas de Arena Regional Park

Learn more about Santa Cruz

Top Santa Cruz Hotel Reviews

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Sun Hotel

Marriott Santa Cruz de la Sierra Hotel

Premium Suites Deluxe Aparthotel Equipetrol

Camino Real Hotel

Ibis Santa Cruz DE LA Sierra

Hotel Cortez

Hotel LP Equipetrol

Alfonsina Hotel Boutique by Inboccaluppo

More cheap stays in Santa Cruz

Ibiza Hostel

Equipetrol Suites Apart Hotel

Amaca Hostal

Casa Por Temporadas

HOTEL CASA BLANCA

Hotel Viru Viru II

Frequently asked questions

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