Find hotels in Santa Cruz de la Sierra from ￥9,946

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Dec 10 - Dec 11
Tomorrow
Dec 11 - Dec 12
This weekend
Dec 12 - Dec 14
Next weekend
Dec 19 - Dec 21

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Our top choices for Santa Cruz de la Sierra hotels

Outdoor pool
Eurostars Palacio Santa Marta

Eurostars Palacio Santa Marta

4.0 star property
Trujillo
9.2 out of 10, Wonderful, (327)
"Just excellent, Service from all staff is perfect "
Mexico
Jor
The price is ￥10,358
￥11,394 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Eurostars Palacio Santa Marta
Seasonal outdoor pool, sun loungers
Hotel Izan Trujillo

Hotel Izan Trujillo

4.0 star property
Trujillo
8.8 out of 10, Excellent, (209)
"We enjoyed our stay, albeit just for one night. Nice hotel. Totally recommend. "
United Kingdom
Younes
The price is ￥11,161
￥12,277 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Hotel Izan Trujillo
Front of property
Finca la Desa

Finca la Desa

3.0 star property
Miajadas
9.6 out of 10, Exceptional, (5)
"Buenas situación , personal amable y buena comida"
Spain
José Jesús
The price is ￥12,495
￥13,744 total
includes taxes & fees
Dec 17 - Dec 18
Finca la Desa
Hallway
Parador de Trujillo

Parador de Trujillo

4.0 star property
Trujillo
9.2 out of 10, Wonderful, (222)
"Very nice hotel, good parking, well located, "
United States
Edgar
The price is ￥12,384
￥13,622 total
includes taxes & fees
Dec 14 - Dec 15
Parador de Trujillo
Seasonal outdoor pool, sun loungers
Finca El Azahar

Finca El Azahar

3.0 star property
Trujillo
10.0 out of 10, Exceptional, (6)
"Stunning, warm, beautiful, "
Canada
Alex
The price is ￥25,910
￥28,501 total
includes taxes & fees
Dec 12 - Dec 13
Finca El Azahar
Property grounds
Hostal León

Hostal León

2.0 star property
Trujillo
7.6 out of 10, Good, (51)
"Limpio y bien situado, porque está a 10 min o menos andando de la plaza mayor y está en un sitio donde se puede aparcar bien. Más hsvia el casco antiguo parecía difícil poder dejar el coche. Además, tiene aparcamiento cerca, de pago. La habitación suficiente para lo que era, visitar Trujillo, muy zona tranquila para dormir. Eso sí, hay escaleras para subir a las habitaciones, no vimos ascensor (a tener en cuenta si se va con personas con movilidad reducida). "
Spain
David
The price is ￥9,042
￥9,946 total
includes taxes & fees
Dec 10 - Dec 11
Hostal León
Lobby
Hospedium Hotel Soterraña

Hospedium Hotel Soterraña

3.0 star property
Madronera
8.8 out of 10, Excellent, (37)
"Kostenloser Parkplatz und Sauberkeit sind positiv hervorzuheben. Der Ort bietet so gut eie nichts. Wir waren im Nebengebäude untergebracht. Man kommt sich abgeschoben vor, weil es Personal und Frühstück nur im Haupthaus auf der anderen Straßenseite gibt. Das Zimmer war sehr dunkel (dunkle Einrichtung, kleines Fenster, unzureichendes Lampenlicht). Abendessen gibt es erst ab 20.00 Uhr. "
Germany
Bärbel
The price is ￥11,263
￥12,389 total
includes taxes & fees
Dec 10 - Dec 11
Hospedium Hotel Soterraña
Breakfast, lunch, dinner served; Regional cuisine
Hostal Hueso

Hostal Hueso

2.0 star property
Trujillo
8.2 out of 10, Very Good, (23)
"Excelent location, excelent staf"
United States
ALFRED
The price is ￥9,865
￥10,851 total
includes taxes & fees
Dec 10 - Dec 11
Hostal Hueso
Outdoor pool, sun loungers
Plaza Sandra

Plaza Sandra

3.0 star property
Trujillo
9.6 out of 10, Exceptional, (51)
"Good staff and beautiful place "
United States
Juan
Plaza Sandra
Coffee shop
Hospedium Hotel Triana

Hospedium Hotel Triana

3.0 star property
Miajadas
7.8 out of 10, Good, (19)
"This is a very convenient stop-over between Santander and Barbate/Vejer/Conil where we were staying. Simple, clean room,super helpful staff and great food at an amazing price. Free car parking in a plot next to the hotel. We've stayed here before and will do so again."
United Kingdom
tina
The price is ￥13,251
￥14,576 total
includes taxes & fees
Dec 18 - Dec 19
Hospedium Hotel Triana
Exterior
Alojamientos Plaza Mayor

Alojamientos Plaza Mayor

3.0 star property
Trujillo
8.0 out of 10, Very Good, (55)
"Susana was very friendly and wait for us to give us the keys. Great location in front of main plaza. Basic room, very clean. Room was located in third floor, no elevator. Overall very good experience "
United States
Adela
The price is ￥9,097
￥10,006 total
includes taxes & fees
Dec 17 - Dec 18
Alojamientos Plaza Mayor
Food court
Casa Rural Las Canteras

Casa Rural Las Canteras

3.0 star property
Trujillo
8.2 out of 10, Very Good, (33)
"Limpieza correcta "
Spain
Carlos
The price is ￥14,632
￥16,095 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Casa Rural Las Canteras
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Cruz de la Sierra Hotel Reviews

Hotel Izan Trujillo

Hotel Izan Trujillo

10/10 Excellent
"All very good"
Lance 1-night trip
Posted 3 weeks ago
Hotel Izan Trujillo

More cheap stays in Santa Cruz de la Sierra

Hostal León

Hostal León

Campillo 11 Trujillo Caceres
The price is ￥9,042 per night from Dec 10 to Dec 11
￥9,042
￥9,946 total
Dec 10 - Dec 11
includes taxes & fees
7.6/10 Good! (50 reviews)

Frequently asked questions

What's the best place to stay in Santa Cruz de la Sierra?
Parador de Trujillo, located 0.1 mi (0.1 km) from the heart of Santa Cruz de la Sierra, is a top choice for your stay based on our traveler data. Other good options for your stay in the area are Eurostars Palacio Santa Marta and Finca la Desa. See all available top hotels, or vacation rentals in Santa Cruz de la Sierra.
What's the top vacation rental in Santa Cruz de la Sierra?
Rural house with swimming pool El Huerto del Olivo, Plasenzuela, Trujillo, Cáceres: This vacation home near Santa Cruz de la Sierra is equipped with a barbecue grill, air-conditioning, and laundry facilities to help you feel comfortable during your stay. Kitchen amenities include a dishwasher, a stovetop, and a microwave. See all vacation rentals in Santa Cruz de la Sierra.
If I need to cancel my hotel reservation in Santa Cruz de la Sierra, will I receive a refund?
Yes! Most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you have a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz de la Sierra.
Where can I learn more about changing or cancelling my trip to Santa Cruz de la Sierra?
To find more details about updating your trip to Santa Cruz de la Sierra or cancelling it, head over to our customer service page.
What are some accommodations with pools in Santa Cruz de la Sierra?
Parador de Trujillo: Offers a snack bar/deli, a seasonal outdoor pool, and complimentary wired internet access. Another choice that features an onsite pool is Rural house (full rental) El Olivar del Marqués for 26 people. View all hotels with pools in Santa Cruz de la Sierra.
What's the best accommodation near Adolfo Suarez Madrid-Barajas Airport (MAD)?
Madrid Marriott Auditorium Hotel & Conference Center is a popular 4-star hotel featuring 2 restaurants and 2 bars. It's located a short 1.4 mi (2.2 km) from Adolfo Suarez Madrid-Barajas Airport. Other accommodations close to the airport are Hotel Clement Barajas and Meliá Barajas.
What's it like to stay in Santa Cruz de la Sierra?
Those traveling to Santa Cruz de la Sierra are sure to enjoy the sights to see and things to do. In Santa Cruz de la Sierra, there are 9 hotels and other accommodations to choose from. Find out more about Santa Cruz de la Sierra.
What is there to see in Santa Cruz de la Sierra?
Places to visit in the wider area include Juan Pizarro de Orellana Palace, Plaza Mayor, and Trujillo Castle. You'll also find Museo de Vino y Queso and City Walls in the area. Check out what more to see and do in Expedia's Santa Cruz de la Sierra guide.
What's the seasonal weather like in Santa Cruz de la Sierra?
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 47°F. Average annual precipitation for Santa Cruz de la Sierra is 22 inches.

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