A large brick church with two bell towers and palm trees in front.

Find hotels in Santa Cruz de la Sierra from ￥10,174

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Jul 10 - Jul 12
Next weekend
Jul 17 - Jul 19

Filter by

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Property class

Our top choices for Santa Cruz de la Sierra hotels

Garden

Finca la Desa

Finca la Desa
3.0 star property
Miajadas
10.0 out of 10, Exceptional, (16 reviews)
"This is a diamond in the west country of Spain. Everything about this place was exceptional."
New Zealand
Craig
The price is ￥11,261
￥12,387 total
includes taxes & fees
Jul 16 - Jul 17
Finca la Desa
Ballroom

Hotel Izan Trujillo

Hotel Izan Trujillo
4.0 star property
Trujillo
8.6 out of 10, Excellent, (213 reviews)
"Friendly staff, good buffet breakfast, comfortable room. "
United Kingdom
Malcolm
The price is ￥11,417
￥12,558 total
includes taxes & fees
Jul 13 - Jul 14
Hotel Izan Trujillo
Lunch and dinner served

Hospedium Hotel Triana

Hospedium Hotel Triana
3.0 star property
Miajadas
8.0 out of 10, Very Good, (21 reviews)
"This is a very convenient stop-over between Santander and Barbate/Vejer/Conil where we were staying. Simple, clean room,super helpful staff and great food at an amazing price. Free car parking in a plot next to the hotel. We've stayed here before and will do so again."
United Kingdom
tina
The price is ￥13,420
￥14,762 total
includes taxes & fees
Jul 13 - Jul 14
Hospedium Hotel Triana
Breakfast, lunch and dinner served

Hostal Hueso

Hostal Hueso
2.0 star property
Trujillo
8.2 out of 10, Very Good, (26 reviews)
"Excelent location, excelent staf"
United States
ALFRED
The price is ￥9,249
￥10,174 total
includes taxes & fees
Jul 13 - Jul 14
Hostal Hueso
Exterior

Eurostars Palacio Santa Marta

Eurostars Palacio Santa Marta
4.0 star property
Trujillo
9.2 out of 10, Wonderful, (348 reviews)
"Beautiful hotel in the center of the old town. Staff are superb "
United States
robert
The price is ￥13,284
￥14,612 total
includes taxes & fees
Jul 16 - Jul 17
Eurostars Palacio Santa Marta
Restaurant

Hostal León

Hostal León
2.0 star property
Trujillo
7.6 out of 10, Good, (54 reviews)
"We turned up. No-one there ... Got to speak to a lady. Agreed to cancel with no charge. Expedia took the money anyway."
United Kingdom
Gareth
The price is ￥9,249
￥10,174 total
includes taxes & fees
Jul 12 - Jul 13
Hostal León
Interior

Plaza Sandra

Plaza Sandra
3.0 star property
Trujillo
9.6 out of 10, Exceptional, (57 reviews)
"Easy to follow check in instructions. Parking on the street nearby. Beautiful property right in the old town. Highly recommended!"
United States
Ismael
The price is ￥12,179
￥13,397 total
includes taxes & fees
Jul 26 - Jul 27
Plaza Sandra
Exterior

Parador de Trujillo

Parador de Trujillo
4.0 star property
Trujillo
9.2 out of 10, Wonderful, (238 reviews)
"Very nice hotel, good parking, well located, "
United States
Edgar
The price is ￥15,425
￥16,968 total
includes taxes & fees
Jul 19 - Jul 20
Parador de Trujillo
Exterior

Finca El Azahar

Finca El Azahar
3.0 star property
Trujillo
10.0 out of 10, Exceptional, (7 reviews)
"Stunning, warm, beautiful, "
Canada
Alex
The price is ￥34,145
￥37,560 total
includes taxes & fees
Jul 12 - Jul 13
Finca El Azahar
Apartment | Soundproofing, free WiFi, bed sheets

Hostal Ruralis Altozano

Hostal Ruralis Altozano
1.0 star property
Montánchez
9.0 out of 10, Wonderful, (2 reviews)
"Habitacion muy grande, muebles impecables, muy limpia almigualnque el baño. Todo perfecto.hitel.con oarking en centro de Montanchez. Arantxa es magnifica y un encanto. Llegamos muy tarde y nos atendio dejandolo todo preparado. Llaves, telefonos de contacto, etc. REPETIREMOS SIN LUGAR A DUDAS"
Spain
MARCO ANTONIO
The price is ￥9,395
￥10,334 total
includes taxes & fees
Jul 9 - Jul 10
Hostal Ruralis Altozano
Terrace/patio

Hospedium Hotel Soterraña

Hospedium Hotel Soterraña
3.0 star property
Madronera
8.8 out of 10, Excellent, (38 reviews)
"Tiene aparcamiento propio gratuito, la habitación muy bien y el personal excelente. Si restaurante muy buena calidad y buena atención. "
Spain
Ángel
The price is ￥10,949
￥12,044 total
includes taxes & fees
Jul 13 - Jul 14
Hospedium Hotel Soterraña
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Learn more about Santa Cruz de la Sierra

Head to Plaza Mayor and Alfiler Tower—just two of the sights around Santa Cruz de la Sierra.

See all hotels in Santa Cruz de la Sierra
A large brick church with two bell towers and palm trees in front.

Top Santa Cruz de la Sierra Hotel Reviews

Parador de Trujillo

Parador de Trujillo

8/10 Good
"Just at the outskirts of the historical center with easy access with a car and a short walk to the attractions, this hotel offers a comfortable and tranquil place to stay. Rooms are generous in size with comfortable beds. Breakfast is generous with cooked to order eggs."
Oscar 1-night trip
Posted 3 weeks ago
Parador de Trujillo

More cheap stays in Santa Cruz de la Sierra

Hostal León

Hostal León

Campillo 11 Trujillo Caceres
The price is ￥9,249 per night from Jul 12 to Jul 13
￥9,249
￥10,174 total
Jul 12 - Jul 13
includes taxes & fees
7.6/10 Good! (54 reviews)

Frequently asked questions

What's the best place to stay in Santa Cruz de la Sierra?
Eurostars Palacio Santa Marta, located 0.1 mi (0.1 km) from the heart of Santa Cruz de la Sierra, is a top choice for your stay based on our traveler data. Other good options for your stay in the area are Parador de Trujillo and Hotel Izan Trujillo. See all available top hotels, or vacation rentals in Santa Cruz de la Sierra.
What's the top vacation rental in Santa Cruz de la Sierra?
El Edén, Rural House with swimming pool: This vacation home near Santa Cruz de la Sierra offers a balcony, a garden, and air-conditioning to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave. See all vacation rentals in Santa Cruz de la Sierra.
If I need to cancel my hotel reservation in Santa Cruz de la Sierra, will I receive a refund?
Yes! Most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you have a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz de la Sierra.
Where can I learn more about changing or cancelling my trip to Santa Cruz de la Sierra?
To find more details about updating your trip to Santa Cruz de la Sierra or cancelling it, head over to our customer service page.
What are some accommodations with pools in Santa Cruz de la Sierra?
Eurostars Palacio Santa Marta: Offers complimentary wireless internet access, a seasonal outdoor pool, and televisions. Another choice that features an onsite pool is Rural house (full rental) El Olivar del Marqués for 26 people. View all hotels with pools in Santa Cruz de la Sierra.
What's the best accommodation near Adolfo Suarez Madrid-Barajas Airport (MAD)?
Madrid Marriott Auditorium Hotel & Conference Center is a popular 4-star hotel featuring 2 restaurants and 2 bars. It's located a short 1.4 mi (2.2 km) from Adolfo Suarez Madrid-Barajas Airport. Other accommodations close to the airport are Hotel Clement Barajas and Meliá Barajas.
What's it like to stay in Santa Cruz de la Sierra?
Those traveling to Santa Cruz de la Sierra are sure to enjoy the sights to see and things to do. In Santa Cruz de la Sierra, there are 9 hotels and other accommodations to choose from. Find out more about Santa Cruz de la Sierra.
What is there to see in Santa Cruz de la Sierra?
Places to visit in the wider area include Plaza Mayor, Alfiler Tower, and Juan Pizarro de Orellana Palace. You'll also find Palacio de la Conquista and Pizarro House Museum in the area. Check out what more to see and do in Expedia's Santa Cruz de la Sierra guide.
What's the seasonal weather like in Santa Cruz de la Sierra?
The hottest months are usually July and August with an average temp of 77°F, while the coldest months are January and February with an average of 47°F. Average annual precipitation for Santa Cruz de la Sierra is 22 inches.