Find hotels in Santa Ana, Antigua Guatemala from ¥3,511

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Discover 1,135 Santa Ana hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Hostal Casa Buho

3.0 star property
8.4 out of 10, Very Good, (20)
"Nice clean affordable accomodations and very accomodating and amicable hosts."
Hostal Casa Buho

Casa Buho B&B

3.0 star property
9.2 out of 10, Wonderful, (44)
"The hotel is beatifull, much better than pictures, love the gardens and service. Help me with my daughther food desires that is priceless. "
The price is ¥6,082
¥7,420 total
includes taxes & fees
Jul 30 - Jul 31
Casa Buho B&B

Villas Santa Ana-Ricardo

3.5 star property
8.2 out of 10, Very Good, (10)
"Very nice place"
The price is ¥18,941
¥23,109 total
includes taxes & fees
Jul 29 - Jul 30
Villas Santa Ana-Ricardo

Castillo De Los Gigantes

2.0 star property
The price is ¥3,511
¥4,283 total
includes taxes & fees
Jul 29 - Jul 30
Castillo De Los Gigantes

La guarida del caudillo

1.0 star property
The price is ¥4,409
¥5,404 total
includes taxes & fees
Aug 10 - Aug 11
La guarida del caudillo

AC Hotel by Marriott Guatemala City

4.0 star property
8.6 out of 10, Excellent, (1003)
" Good place to stay "
The price is ¥16,194
¥19,757 total
includes taxes & fees
Aug 10 - Aug 11
AC Hotel by Marriott Guatemala City

Hotel Vista Quince

5.0 star property
8.4 out of 10, Very Good, (168)
"Really happy to stayed there. Definitely will stay again. "
The price is ¥16,351
¥20,738 total
includes taxes & fees
Aug 17 - Aug 18
Hotel Vista Quince

Villas Santander - Deluxe Stay

3.0 star property
7.6 out of 10, Good, (172)
"Is perfect place to stay I recommend TJ's place 100/100"
Villas Santander - Deluxe Stay

Casa Mesa

2.0 star property
8.6 out of 10, Excellent, (33)
"Very good option for staying "
The price is ¥6,053
¥7,384 total
includes taxes & fees
Jul 29 - Jul 30
Casa Mesa

Ever Green Hotel

3.5 star property
8.8 out of 10, Excellent, (52)
"It is a decent hotel. I had a very delicious breakfast. Staff is helpful."
Ever Green Hotel

Hotel Antigua Inn

3.5 star property
8.2 out of 10, Very Good, (62)
"Exelente hotel and location and friendly people. "
Hotel Antigua Inn

La Inmaculada Hotel

3.5 star property
9.2 out of 10, Wonderful, (565)
"Loved the view on top of balcony for breakfast!!! "
La Inmaculada Hotel

Hotel Capri

2.5 star property
7.6 out of 10, Good, (46)
"Overall this hotel is very good and I would stay again. It’s quiet and close to Civic centre and historic centre "
The price is ¥5,102
¥6,224 total
includes taxes & fees
Aug 18 - Aug 19
Hotel Capri

Hotel Ciudad Vieja

3.0 star property
9.0 out of 10, Wonderful, (199)
"Only 15 minutes to the airport by Uber. Also close to museums. The breakfast was a plus. Friendly staff and security "
Hotel Ciudad Vieja

Meraki Boutique Hotel

3.5 star property
9.0 out of 10, Wonderful, (358)
"Excellent place to stay "
The price is ¥11,926
¥14,550 total
includes taxes & fees
Jul 29 - Jul 30
Meraki Boutique Hotel

Hotel Santander Plaza

3.5 star property
8.2 out of 10, Very Good, (532)
"Clean and great breakfast "
The price is ¥15,507
¥18,919 total
includes taxes & fees
Jul 31 - Aug 1
Hotel Santander Plaza

Clarion Suites Guatemala City

4.0 star property
9.0 out of 10, Wonderful, (1016)
"Very nice clean safe and comfortable hotel."
The price is ¥15,507
¥18,919 total
includes taxes & fees
Aug 1 - Aug 2
Clarion Suites Guatemala City

Good Hotel Guatemala City

3.0 star property
9.4 out of 10, Exceptional, (205)
"Very nice for a quick stay in the city. "
The price is ¥12,511
¥15,263 total
includes taxes & fees
Aug 1 - Aug 2
Good Hotel Guatemala City

Hyatt Centric Guatemala City

4.5 star property
9.6 out of 10, Exceptional, (715)
"Great stay"
The price is ¥18,875
¥23,027 total
includes taxes & fees
Aug 15 - Aug 16
Hyatt Centric Guatemala City

Best Western Plus Hotel Stofella

4.0 star property
8.8 out of 10, Excellent, (1009)
"Great place to stay close to the airport"
The price is ¥13,256
¥17,499 total
includes taxes & fees
Aug 8 - Aug 9
Best Western Plus Hotel Stofella
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Santa Ana

Find the best Santa Ana areas and neighborhoods for the activities you enjoy most.
Historic Center map

Historic Center

3 out of top 10 points of interest in this area

While visiting Historic Center, you might make a stop by sights like Central Park and Antigua Guatemala Cathedral.

Barrio de La Concepción map

Barrio de La Concepción

1 out of top 10 points of interest in this area

While visiting Barrio de La Concepción, you might make a stop by sights like Casa Santo Domingo Museum and Jade Maya Factory and Museum.

Top Santa Ana Hotel Reviews

Frequently asked questions

What's it like in Santa Ana?

Travelers to the Santa Ana neighborhood in Antigua Guatemala will be sure to enjoy their stay.

What's a favorite hotel to stay in Santa Ana?

Based on Expedia customer reviews, Casa Buho B&B is the highest ranked property in Santa Ana. This hotel offers a restaurant and free parking. Another top choice in the area is Hostal Casa Buho.

How many hotels will I be able to find in Santa Ana?

If you're searching for places to stay in Antigua Guatemala, choose from one of Expedia's 19 hotels and other accommodations in Santa Ana.

If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?

Yes! You'll find that most hotel bookings are fully refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to review the top deals on offer in Santa Ana.

Where can I learn more about changing or cancelling my trip to Santa Ana?

To find more details about updating your trip to Santa Ana or cancelling it, click here.

What are the top things to see and do in Santa Ana?

Iglesia de la Escuela de Cristo, Church of San Francisco, and House of the Giants are just a few of the places to visit in and around Santa Ana. While you're out sightseeing in Antigua Guatemala, be sure to visit other sights like Santa Clara Convent or Jade Maya Factory and Museum.