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Compare 1,014 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Hotel Museo Spa Casa Santo Domingo
View from property
Hotel Museo Spa Casa Santo Domingo
4.5 star property
9.2 out of 10, Wonderful, (1001)
"Best Hotel in Antigua Guatemala. Peaceful and relaxing. "
The price is ￥33,243
per night
Jun 4 - Jun 5
Hotel Museo Spa Casa Santo Domingo
Porta Hotel Antigua
Property amenity
Porta Hotel Antigua
4.5 star property
9.2 out of 10, Wonderful, (899)
"Beautiful pool and grounds, family friendly. Great buffet breakfast which is not included. Easy walk to the main square, beautiful views of Vulcan Aqua."
The price is ￥25,216
per night
May 27 - May 28
Porta Hotel Antigua
Hotel Soleil La Antigua
3 outdoor pools, pool umbrellas
Hotel Soleil La Antigua
4.0 star property
8.4 out of 10, Very Good, (1002)
"Amazing hotel! Would definitely stay here again when in Antigua again! "
The price is ￥19,399
per night
Jun 9 - Jun 10
Hotel Soleil La Antigua
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Hotel Camino Real Antigua
Bar (on property)
Hotel Camino Real Antigua
4.0 star property
9.6 out of 10, Exceptional, (913)
"Excellent experience, I will back "
The price is ￥25,768
per night
May 16 - May 17
Hotel Camino Real Antigua
El Carmen Hotel
Courtyard view
El Carmen Hotel
3.0 star property
8.6 out of 10, Excellent, (380)
"A quaint very clean and cozy hotel with close proximity to top restaurants and easy access to jade museum, the park, key monuments and shopping. "
The price is ￥13,297
per night
May 21 - May 22
El Carmen Hotel
Hotel Boutique Los Pasos & Spa
Terrace/patio
Hotel Boutique Los Pasos & Spa
4.5 star property
9.4 out of 10, Exceptional, (857)
"Beautiful place, excellent rooms, location is easy to walk around. We loved the restaurant (Thank you Precila). front desk were helpful in setting up shuttle and taxies. Friendly and sweet! "
The price is ￥21,329
per night
May 16 - May 17
Hotel Boutique Los Pasos & Spa
Santo Cielo by Casa Santo Domingo
In-room safe, free WiFi, bed sheets
Santo Cielo by Casa Santo Domingo
3.5 star property
9.2 out of 10, Wonderful, (393)
"the campers are amazing, so much fun. I loved staying at Santo Cielo, I think Santo Domingo is just an excellent deal all around, "
The price is ￥28,121
per night
May 27 - May 28
Santo Cielo by Casa Santo Domingo
El Convento Boutique Hotel
Premium Suite, 1 King Bed | Egyptian cotton sheets, premium bedding, minibar, in-room safe
El Convento Boutique Hotel
4.0 star property
9.4 out of 10, Exceptional, (598)
"Beautiful hotel with kind staff, very well kept. Quiet, peaceful, and romantic"
The price is ￥28,087
per night
May 21 - May 22
El Convento Boutique Hotel
Hotel Casa del Parque
Aerial view
Hotel Casa del Parque
3.5 star property
8.2 out of 10, Very Good, (296)
"I had a great stay over 4 days in Antigua. The pool was perfect to cool down in the afternoon. I stayed from Monday to Friday so the noise from the bar some have mentioned wasn’t bad. The staff were friendly and attentive. I already miss my room and Antigua. "
The price is ￥13,087
per night
May 16 - May 17
Hotel Casa del Parque
Good Hotel Antigua
Deluxe Double Room, Patio, Garden View | Terrace/patio
Good Hotel Antigua
4.0 star property
9.2 out of 10, Wonderful, (390)
"Such a cute and peaceful place!! But no AC :("
The price is ￥19,655
per night
May 20 - May 21
Good Hotel Antigua
Las Camelias Inn
Interior
Las Camelias Inn
3.0 star property
8.6 out of 10, Excellent, (348)
"Nice staff, hotel well situated in the city."
The price is ￥8,510
per night
Jun 2 - Jun 3
Las Camelias Inn
Hotel La Catedral
Terrace/patio
Hotel La Catedral
4.0 star property
9.4 out of 10, Exceptional, (450)
"Very helpful staff. Good bed and shower"
The price is ￥18,069
per night
May 16 - May 17
Hotel La Catedral
Pensativo House Hotel
Banquet hall
Pensativo House Hotel
4.5 star property
9.4 out of 10, Exceptional, (319)
"Very nice hotel with a cute courtyard and rooftop area. Staff was great and suite had ample space and amenities. "
The price is ￥27,751
per night
May 20 - May 21
Pensativo House Hotel
El Carmen Suites
Courtyard
El Carmen Suites
2.5 star property
8.2 out of 10, Very Good, (181)
"Great comfortable place to stay, nice staff, 10/10"
The price is ￥8,451
per night
May 16 - May 17
El Carmen Suites
Hotel Posada de Don Rodrigo Antigua
Exterior
Hotel Posada de Don Rodrigo Antigua
3.5 star property
9.2 out of 10, Wonderful, (375)
"Lovely! "
The price is ￥17,083
per night
May 23 - May 24
Hotel Posada de Don Rodrigo Antigua
Hotel Las Farolas
Breakfast, lunch, dinner served; Regional cuisine, garden views
Hotel Las Farolas
3.5 star property
9.2 out of 10, Wonderful, (560)
" The only Is not 6 minutes walking to central park is a least 15 minutes "
The price is ￥11,509
per night
Jun 13 - Jun 14
Hotel Las Farolas
Villa Bokeh - Relais & Chateaux
Indoor pool, outdoor pool, sun loungers
Villa Bokeh - Relais & Chateaux
4.0 star property
9.8 out of 10, Exceptional, (46)
"Excellent!!!"
The price is ￥35,199
per night
May 16 - May 17
Villa Bokeh - Relais & Chateaux
Adra Hostel
Terrace/patio
Adra Hostel
2.0 star property
9.2 out of 10, Wonderful, (59)
"My 1st time at a hostel. Im glad I chose this one. Everyone was so friendly and helpful. "
Adra Hostel
Hotel Convento Santa Catalina
Front of property
Hotel Convento Santa Catalina
3.5 star property
7.8 out of 10, Good, (264)
"Super central quiet hotel with an amazing restaurant! Love this place!"
The price is ￥10,519
per night
Jun 3 - Jun 4
Hotel Convento Santa Catalina
Nico Hotel
Traditional Single Room, 1 Queen Bed | Laptop workspace, iron/ironing board, free WiFi, bed sheets
Nico Hotel
3.0 star property
9.2 out of 10, Wonderful, (102)
"Amazingly cozy and the location perfect to get around to all the local spots. Breakfast is delicious and made fresh every morning. They go above and beyond to make sure you are happy and well taken care of. Even with all the excitement of a weekend in Antigua, the hotel was still quiet and we never had any issues! A perfectly quaint and lovely hotel."
The price is ￥10,325
per night
May 16 - May 17
Nico Hotel
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Frequently asked questions

What's the best place for a stay in Santa Ana?

Based on our traveler data, Casa Buho B&B is one of the top choices for your stay. This hotel offers a restaurant and free parking. Other good choices for your trip to the area are Barceló Guatemala City and Wyndham Garden Guatemala City. See all available top hotels, or vacation rentals in Santa Ana.

What's the top vacation rental in Santa Ana?

Casa Antigua: You might like this vacation home rental near Santa Ana. It is equipped with a garden, air-conditioning, and free WiFi to help you feel comfortable during your stay. This vacation rental also comes with free parking to give you added peace of mind. See all vacation rentals in Santa Ana.

If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?

Yes, the majority of hotel reservations are refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If your reservation is non-refundable, you might still have the option to cancel and receive a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Ana.

Where can I learn more about changing or cancelling my trip to Santa Ana?

For more details about changing or cancelling your trip to Santa Ana, click here.

What's the best accommodation for a family trip to Santa Ana?

Villas Santa Ana-Ricardo is a top 3.5-star villa on Expedia for families, and features in-room kitchens and free parking. Attractions in the area like La Aurora Zoo and Casa K'Ojom Museum of Mayan Music are also fun for kids of all ages.

What's the best pet-friendly hotel in Santa Ana?

Royal Santa Ana is a top dog-friendly hotel, and offers an outdoor pool along with free WiFi for its human guests. See more pet-friendly hotel accommodations in Santa Ana.

What are some accommodations with pools in Santa Ana?

Barceló Guatemala City: Hotel, 11-minute walk from La Aurora Zoo. Offers 3 restaurants, an outdoor pool, and a full-service spa. Tikal Futura Hotel & Convention Center and Hotel Museo Spa Casa Santo Domingo are a couple of other choices with an onsite pool. View all hotels with pools in Santa Ana.

What is staying in Santa Ana like?

Travelers to Santa Ana will find plenty to explore and enjoy. In Santa Ana, there are 10 hotels and other accommodations to choose from. Find out more about Santa Ana.

What is there to see in Santa Ana?

Places to visit in the wider area include Santa Clara Convent, Casa Santo Domingo Museum, and Antigua Guatemala Colonial Art Museum. You'll also find Antigua Guatemala Cathedral and Central Park in the area. Check out what more to see and do in Expedia's Santa Ana guide.

What's the weather like in Santa Ana?

The hottest months are usually April and March with an average temp of 67°F, while the coldest months are January and December with an average of 64°F. The rainiest months in Santa Ana are September, June, May, and August, with each month seeing an average of 16 inches of rainfall.