Find hotels in Santa Ana, Antigua Guatemala from ￥4,527

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Nov 12 - Nov 13
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Discover 1,225 Santa Ana hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Interior
Casa Buho B&B

Casa Buho B&B

3.0 star property
Santa Ana
9.2 out of 10, Wonderful, (46)
"All was very good and True to the pictures "
United States
Xavier
The price is ￥8,578
￥10,465 total
includes taxes & fees
Dec 9 - Dec 10
Casa Buho B&B
Garden view
Hostal Casa Buho

Hostal Casa Buho

3.0 star property
Santa Ana
8.6 out of 10, Excellent, (21)
"Las instalaciones están muy bien solo que sí está lejos del centro de Antigua "
Mexico
LUIS FERNANDO
Hostal Casa Buho
Front of property
Villas Santa Ana-Ricardo

Villas Santa Ana-Ricardo

3.5 star property
Santa Ana
8.4 out of 10, Very Good, (11)
"We loved this house the view was wonderful "
United States
Emely
Villas Santa Ana-Ricardo
Living area
La guarida del caudillo

La guarida del caudillo

1.0 star property
Santa Ana
The price is ￥3,592
￥4,527 total
includes taxes & fees
Dec 13 - Dec 14
La guarida del caudillo
Reception hall
Barceló Guatemala City

Barceló Guatemala City

4.5 star property
22.7 km from Santa Ana
9.2 out of 10, Wonderful, (3077)
"This is my second stay here and the staff amenities are vey good "
United States
Kevin
The price is ￥12,509
￥15,261 total
includes taxes & fees
Dec 7 - Dec 8
Barceló Guatemala City
3 outdoor pools, pool umbrellas
Hotel Soleil La Antigua

Hotel Soleil La Antigua

4.0 star property
1.8 km from Santa Ana
8.6 out of 10, Excellent, (1000)
"Great place to stay"
United States
Edwin
Hotel Soleil La Antigua
Fitness studio
Hotel Museo Spa Casa Santo Domingo

Hotel Museo Spa Casa Santo Domingo

4.5 star property
Barrio de La Concepción, 1.1 km from Santa Ana
9.2 out of 10, Wonderful, (1001)
"Great overall stay"
United States
Jose
The price is ￥40,348
￥51,379 total
includes taxes & fees
Nov 13 - Nov 14
Hotel Museo Spa Casa Santo Domingo
Terrace/patio
Los Pasos Boutique Hotel & Spa

Los Pasos Boutique Hotel & Spa

4.5 star property
0.7 km from Santa Ana
9.4 out of 10, Exceptional, (1004)
"Great place to stay. "
United States
tania
The price is ￥22,661
￥27,854 total
includes taxes & fees
Dec 3 - Dec 4
Los Pasos Boutique Hotel & Spa
Egyptian cotton sheets, premium bedding, in-room safe, desk
El Convento Boutique Hotel

El Convento Boutique Hotel

4.0 star property
Historic Center, 1.5 km from Santa Ana
9.4 out of 10, Exceptional, (785)
"Super comfortable stay, loved the atmosphere and the restaurant was great. Would def go here again"
United States
Richard
The price is ￥30,504
￥39,525 total
includes taxes & fees
Dec 3 - Dec 4
El Convento Boutique Hotel
Outdoor pool
Hyatt Centric Guatemala City

Hyatt Centric Guatemala City

4.5 star property
23.3 km from Santa Ana
9.6 out of 10, Exceptional, (767)
"Excelente Hotel "
Mexico
Blanca
The price is ￥22,814
￥27,833 total
includes taxes & fees
Dec 6 - Dec 7
Hyatt Centric Guatemala City
Breakfast, lunch, dinner served; international cuisine, garden views
Clarion Suites Guatemala City

Clarion Suites Guatemala City

4.0 star property
23.3 km from Santa Ana
9.0 out of 10, Wonderful, (1004)
"Room was so clean and all the staff was so friendly "
United States
Irsa
The price is ￥16,176
￥19,735 total
includes taxes & fees
Nov 29 - Nov 30
Clarion Suites Guatemala City
2 treatment rooms
Hotel Las Americas

Hotel Las Americas

4.0 star property
22.3 km from Santa Ana
8.4 out of 10, Very Good, (1003)
"Excellent breakfast, nice room and nice view to the aurora airport "
Mexico
Ronald Fernando Rivera
Hotel Las Americas
4 restaurants, breakfast, lunch, dinner served; international cuisine
InterContinental Real Guatemala by IHG

InterContinental Real Guatemala by IHG

5.0 star property
23.2 km from Santa Ana
9.2 out of 10, Wonderful, (1001)
"Clean room and amenities"
United States
Nubia
The price is ￥27,423
￥35,336 total
includes taxes & fees
Dec 5 - Dec 6
InterContinental Real Guatemala by IHG
Exterior
All Suite El Marques de Antigua

All Suite El Marques de Antigua

3.5 star property
1 km from Santa Ana
9.4 out of 10, Exceptional, (288)
"So glad we chose the location, wish we had moretime to spend there."
United States
Max
All Suite El Marques de Antigua
Exterior
Hotel Posada de Don Rodrigo Antigua

Hotel Posada de Don Rodrigo Antigua

3.5 star property
Historic Center, 1.5 km from Santa Ana
9.4 out of 10, Exceptional, (633)
"Lovely hotel, good food. "
United Kingdom
Lucy
The price is ￥24,074
￥33,293 total
includes taxes & fees
Nov 26 - Nov 27
Hotel Posada de Don Rodrigo Antigua
Terrace/patio
In & Out Hotel

In & Out Hotel

3.0 star property
20.9 km from Santa Ana
8.4 out of 10, Very Good, (790)
"Breakfast included "
United States
Chelsea
In & Out Hotel
Exterior
Naif Boutique Hotel

Naif Boutique Hotel

3.0 star property
Historic Center, 1.4 km from Santa Ana
8.8 out of 10, Excellent, (361)
"Terrible"
United States
Eddie
The price is ￥18,746
￥22,871 total
includes taxes & fees
Nov 18 - Nov 19
Naif Boutique Hotel
Property amenity
Porta Hotel Antigua

Porta Hotel Antigua

4.5 star property
1.1 km from Santa Ana
9.4 out of 10, Exceptional, (1005)
"Outstanding hotel and location, my family and I had a blast, super friendly staff, extremely clean rooms and amenities, easy transportation from hotel to parking or viceversa, the food is exceptional a bit pricey but worth every penny! "
United States
Frank
The price is ￥24,981
￥32,018 total
includes taxes & fees
Nov 17 - Nov 18
Porta Hotel Antigua
Restaurant
Villas Santander - Deluxe Stay

Villas Santander - Deluxe Stay

3.0 star property
24.5 km from Santa Ana
7.6 out of 10, Good, (203)
"Great stay staff was nice The only one thing is it’s not noise proof. You do hear everything. But other than that great place will go again !!! "
United States
Elias
The price is ￥4,886
￥5,961 total
includes taxes & fees
Nov 16 - Nov 17
Villas Santander - Deluxe Stay
Exterior
Hotel Casa Carmina

Hotel Casa Carmina

4.0 star property
1.2 km from Santa Ana
9.0 out of 10, Wonderful, (189)
"Great place to stay the staff were very friendly and welcoming "
United States
Vanessa Sanchez
The price is ￥18,963
￥23,264 total
includes taxes & fees
Nov 14 - Nov 15
Hotel Casa Carmina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Hotels in Santa Ana with free breakfast

Garden view
Hostal Casa Buho
Hostal Casa Buho
3.0 star property
  • Breakfast included
8.6 out of 10, Excellent, (21)
Hostal Casa Buho
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Hotels in Santa Ana with a pool

Fridge, microwave, stovetop, dishwasher
Beautiful 2 Bedroom Apartment 5 min walk from Cayala
Beautiful 2 Bedroom Apartment 5 min walk from Cayala
  • Pool
2.0 out of 10, (1)
The price is ￥11,555
￥16,177 total
includes taxes & fees
Nov 17 - Nov 18
Beautiful 2 Bedroom Apartment 5 min walk from Cayala
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Top guest rated hotels in Santa Ana

Front of property
Villas Santa Ana-Ricardo
Villas Santa Ana-Ricardo
3.5 star property
    8.4 out of 10, Very Good, (11)
    Villas Santa Ana-Ricardo
    See more properties

    Where to stay in Santa Ana

    Find the best Santa Ana areas and neighborhoods for the activities you enjoy most.

    Historic Center

    While visiting Historic Center, you might make a stop by sights like Central Park and Santa Catalina Arch.

    Barrio de La Concepción

    While visiting Barrio de La Concepción, you might make a stop by sights like Casa Santo Domingo Museum and Jade Maya Factory and Museum.

    Top Santa Ana Hotel Reviews

    Wyndham Garden Guatemala City

    Wyndham Garden Guatemala City

    10/10 Excellent
    "Everything was great"
    Alison 2-night trip
    Posted 21 hours ago
    Wyndham Garden Guatemala City

    Explore a world of travel with Expedia

    Frequently asked questions

    What's it like in Santa Ana?
    Travelers to the Santa Ana neighborhood in Antigua Guatemala will be sure to enjoy their stay.
    What's a favorite hotel to stay in Santa Ana?
    Based on Expedia customer reviews, Casa Buho B&B is the highest ranked property in Santa Ana. This hotel offers a restaurant and free parking.
    How many hotels will I be able to find in Santa Ana?
    If you're searching for places to stay in Antigua Guatemala, choose from one of Expedia's 18 hotels and other accommodations in Santa Ana.
    If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
    Yes! You'll find that most hotel bookings are fully refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to review the top deals on offer in Santa Ana.
    Where can I learn more about changing or cancelling my trip to Santa Ana?
    To find more details about updating your trip to Santa Ana or cancelling it, click here.
    What are the top things to see and do in Santa Ana?
    House of the Giants, Santa Clara Convent, and Jade Maya Factory and Museum are just a few of the places to visit in and around Santa Ana. While you're out sightseeing in Antigua Guatemala, be sure to visit other sights like Tanque La Unión or Museo del Hermano Pedro.