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Pythagorio Vacation Rentals

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Check prices for these dates

In two weeks
Jan 9 - Jan 11
In two months
Feb 20 - Feb 22
In three months
Mar 20 - Mar 22
In four months
Apr 17 - Apr 19

Our top choices for Pythagorio vacation rentals

Seasonal outdoor pool, pool umbrellas, sun loungers
Scorpios Hotel & Suites

Scorpios Hotel & Suites

Scorpios Hotel & Suites
3.0 star property
Samos
8.8 out of 10, Excellent, (19)
"It has a very nice view to the ocean and great quality of services "
Mexico
Karla
The price is ￥15,928
￥17,725 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Scorpios Hotel & Suites
Traditional Villa | Terrace/patio
Villa of the old olive oil factory

Villa of the old olive oil factory

Villa of the old olive oil factory
Samos
8.0 out of 10, Very Good, (6)
"Service de ménage catastrophique mais proprietaire reactif suite a des problemes d enlèvement des courses personnelles lors d un passage"
France
Bruno Michel
Villa of the old olive oil factory
Beach
Eva's Apartments

Eva's Apartments

Eva's Apartments
Karlovasi
The price is ￥12,857
￥17,449 total
includes taxes & fees
Dec 27 - Dec 28
Eva's Apartments
Private kitchen
THALIA'S COTTAGE

THALIA'S COTTAGE

THALIA'S COTTAGE
Samos
10.0 out of 10, Exceptional, (1)
"Bel emplacement stratégique pour visiter l île. Maison confortable, propre et tranquille.Super hôte Un grand merci "
France
FREDDY B.
The price is ￥22,041
￥25,347 total
includes taxes & fees
Dec 27 - Dec 28
THALIA'S COTTAGE
Beach
Seacret too by Villa Glyfos

Seacret too by Villa Glyfos

Seacret too by Villa Glyfos
Charavgi
The price is ￥36,735
￥50,143 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Seacret too by Villa Glyfos
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Pythagorio Hotel Reviews

Casa Cook Samos

Casa Cook Samos

10/10 Excellent
"Clean and modernly decorated rooms with all the facilities"
Aylin 3-night trip
Posted 2 months ago
Casa Cook Samos

Find out more about Pythagorio

Search for holiday rentals in Pythagorio on Expedia! You can easily find your home rentals, villas, holiday apartments in Pythagorio using one of the methods below:

  • View our selection of featured holiday rentals in Pythagorio
  • Use the map to find apartments and other holiday homes in the Pythagorio neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Pythagorio while they last

Look no further and take a look at our great range of rental properties in Pythagorio!

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Frequently asked questions

Can I find vacation rentals in Pythagorio?

Yes, we give you a choice of vacation rentals near well known points of interest in Pythagorio, or you can go with a more secluded option if you're looking for relaxation. Discover why Pythagorio is known for its waterfront and seaside. Make sure you have time to check out the monuments and museums during your trip.

What are some of the best vacation rentals that Pythagorio has to offer?

Astonishing house with sea view in Samos Island: Located near Pythagorio, this vacation home rental offers a balcony, a garden, and cable TV to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, an oven, and a coffee maker.

How many vacation rentals will I find in Pythagorio?

With 5 Expedia vacation rentals, you're sure to find just the right place for your Pythagorio stay.

What can I see and do in Pythagorio?

Enjoy the outdoors at Glicorisa Beach and İreo beach, or simply take in cultural attractions like Folklore Museum of Samos and Nikolaos Dimitriou Folklore Museum. Other places in town to visit include Samos Pythagorion Archaeological Museum and Pythagoreion.

What are vacation rentals like in Pythagorio?

Vacation rentals are privately owned properties you can stay in for a short or long stay in Pythagorio. Vacation rentals feature amenities such as kitchens and laundry facilities so you'll have all the comforts of home. If you're concerned about a sanitized environment, vacation rentals can offer a sense of security away from shared hotel elevators and busy front desks while still allowing you a great travel experience. You'll also get more space in a vacation rental than in a standard hotel, which makes a vacation rental a popular choice for families.