Photo by Erdem Yücel

Find hotels in Pythagorio from ¥10,304

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Our top choices for Pythagorio hotels

Scorpios Hotel & Suites

Scorpios Hotel & Suites
3.0 star property
Samos
8.8 out of 10, Excellent, (19)
Discover Greek island tranquility at this Samos aparthotel near Gagou Beach. Elegant apartments feature Egyptian cotton sheets and Select Comfort beds. Refresh at the seasonal outdoor pool before enjoying drinks at the beach bar.

"It has a very nice view to the ocean and great quality of services "
Mexico
Karla
The price is ¥15,971
¥17,772 total
includes taxes & fees
Dec 28 - Dec 29
Scorpios Hotel & Suites

Samos Hotel

Samos Hotel
3.0 star property
Samos
7.6 out of 10, Good, (231)
Enjoy island tranquility at this Samos hotel offering an outdoor pool with poolside bar. Unwind with drinks from the bar/lounge or grab a bite at the café. Just minutes from Port of Samos, the hotel includes free WiFi, parking, and 24-hour fitness access.

"Central location Extremely small rooms for two single beds. "
United States
Phyllis
The price is ¥11,937
¥13,352 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Samos Hotel

Villa of the old olive oil factory

Villa of the old olive oil factory
Samos
8.0 out of 10, Very Good, (6)
"Service de ménage catastrophique mais proprietaire reactif suite a des problemes d enlèvement des courses personnelles lors d un passage"
France
Bruno Michel
Villa of the old olive oil factory

Hotel Aria

Hotel Aria
1.0 star property
Samos
6.6 out of 10, (30)
Just steps from Samos Port, this well-maintained hotel offers easy access to the Samos Archaeological Museum. Enjoy a drink at the bar after exploring nearby attractions. Free WiFi and parking enhance your Greek island stay.

"uygun fiyata merkezi yerde sadece uyumak için ideal bir otel. İşletmecisi orta yaşlarda bir teyze çok tatlı ve misafirperver... "
Turkey
Nuran
Hotel Aria

Erato by Samian Mare

Erato by Samian Mare
4.0 star property
Samos
9.2 out of 10, Wonderful, (18)
Experience Samos Island charm at this spa hotel featuring 2 outdoor pools and a poolside bar. Enjoy local cuisine at Samian Mare Restaurant, then relax with deep-tissue massages. The Karlovasi museums are nearby, with free breakfast, WiFi and parking included.

"Great stay! The staff was very helpful with booking taxis for us. The breakfast was great too!"
United States
Anonymous traveler
The price is ¥20,275
¥22,764 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Erato by Samian Mare

Aegeon

Aegeon
3.0 star property
Samos
7.6 out of 10, Good, (19)
Bask in Mediterranean charm at this coastal haven near Karlovasi Tannery Museum. After enjoying the complimentary breakfast, unwind by the outdoor pool or indulge in massages. The restaurant, poolside bar, and free parking enhance your Greek island experience.

"Great pool & outdoor area with a lovely bar"
Australia
Tracey
The price is ¥9,155
¥10,304 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Aegeon
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Pythagorio attractions

Learn more about Pythagorio

The ancient harbor town showcases Pythagoras' legacy at its archaeological museum and the impressive remains of Tunnel of Eupalinos. Waterfront tavernas serve fresh seafood beside bobbing fishing boats, while nearby beaches offer perfect swimming spots.

Energy limonate😋👌
Photo by Erdem Yücel
Open Photo by Erdem Yücel

Top Pythagorio Hotel Reviews

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Frequently asked questions

What's the best place to stay in Pythagorio?
Casa Cook Samos is one of the top choices for your stay based on our traveler data. This hotel offers a full-service spa and 2 bars. Other good options for your trip include Doryssa Seaside Resort and Doryssa Theorem Hotel. See all available top hotels, or vacation rentals in Pythagorio.
What are some of the best vacation rentals that Pythagorio has to offer?
Astonishing house with sea view in Samos Island: Located near Pythagorio, this vacation home rental offers a balcony, a garden, and cable TV to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, an oven, and a coffee maker. See all vacation rentals in Pythagorio.
If I need to cancel my hotel reservation in Pythagorio, will I receive a refund?
Yes, you'll find most room reservations are fully refundable if you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and receive a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Pythagorio.
Where can I learn more about changing or cancelling my trip to Pythagorio?
For more information about updating your trip to Pythagorio or cancelling it, go to https://www.expedia.com/service/.
What's the best hotel for families in Pythagorio?
Anna Studios is a guesthouse with kid-friendly meals and free WiFi, and it's a top choice on Expedia for families. Attractions in the area like Natural History Museum of the Aegean are also fun for the whole family. Find more child-friendly accommodations in Pythagorio.
What is the favorite LGBTQ-friendly hotel in Pythagorio?
Sama is a top LGBTQ-friendly hotel and features private balconies. See all available hotels listed as LGBTQ-friendly in Pythagorio.
What's the best pet-friendly accommodation in Pythagorio?
Casa Cook Samos is a top hotel for people traveling with their pets, and offers a full-service spa and free WiFi for its human guests. Other good options for you and your pet's trip include Doryssa Boutique Hotel and Nisea Hotel Samos. See more pet-friendly hotel accommodations in Pythagorio.
Where is the best place to stay near Samos Pythagorion Archaeological Museum?
Adjacent to Samos Pythagorion Archaeological Museum, Doryssa Seaside Resort is one of the top choices for your stay based on our traveler data, and this 5-star hotel offers 2 outdoor pools and a full-service spa. Other good choices within a short distance include Fito Aqua Bleu Resort and Kallirroi Studios.
What about the best place to stay near Pythagoreion?
One of the top choices for your stay is Doryssa Seaside Resort, located next to Pythagoreion, and this 5-star hotel offers 2 outdoor pools and a full-service spa. Fito Aqua Bleu Resort and Kallirroi Studios are other good choices nearby.
What's the best place for a beach vacation in Pythagorio?
Casa Cook Samos is a top beachfront hotel with a seasonal outdoor pool and free breakfast, and it's located close to Potakaki beach. Other good options to stay near the beach include Proteas Blu Resort - Adults Only and Doryssa Seaside Resort. See more stays near the beach in Pythagorio.
What's the best luxury accommodation in Pythagorio?
Casa Cook Samos is a luxury hotel with a beachfront restaurant and 2 bars, and it's a popular choice for Expedia travelers looking for an elegant place to stay. Proteas Blu Resort - Adults Only and Doryssa Seaside Resort are other upscale choices for your vacation. Find more luxury hotels in Pythagorio.
What's the best boutique hotel in Pythagorio?
Casa Cook Samos is a favorite hotel with Expedia travelers looking for a stylish stay, and features a beachfront restaurant and 2 bars. Doryssa Boutique Hotel and Naftilos are other boutique-style choices. See all boutique hotels in Pythagorio.
What are some accommodations with pools in Pythagorio?
Proteas Blu Resort - Adults Only is a top hotel with an indoor pool, an outdoor pool, and a private beach. View all hotels with pools in Pythagorio.
What is the best spa hotel in Pythagorio?
Casa Cook Samos is a top beach spa hotel featuring a fitness center, a hair salon, a beach bar, and a restaurant. Treat yourself to a facial, body scrub, or Swedish massage at the onsite spa. In-room massages are also available. Other popular spa hotels in Pythagorio include Proteas Blu Resort - Adults Only and Doryssa Seaside Resort. See all spa hotels in Pythagorio.
What's the best hotel for staying near Samos International Airport (SMI)?
Doryssa Seaside Resort is a popular 5-star hotel featuring 2 outdoor pools and a full-service spa. It's located a short 1.5 mi (2.3 km) from Samos Intl. Airport. Other accommodations within close proximity to the airport include Hotel Apollon and Fito Aqua Bleu Resort.
How is it to stay in Pythagorio?
Visitors to Pythagorio are sure to enjoy the seaside. Tourists can also enjoy the city's monuments, museums, and gardens. In Pythagorio, there are 74 hotels and other accommodations to choose from. Find out more about Pythagorio.
What are the top places to visit in Pythagorio?
Cultural venues include Folklore Museum of Samos, Nikolaos Dimitriou Folklore Museum, and Folklore Museum of the Nikolaos Dimitriou Foundation of Samos. Landmarks like Pythagoreion, Castle of Lycurgus, and Panagia Spiliani Monastery might be worth a visit. Natural beauty is on display at Glicorisa Beach, İreo beach, and Potakaki beach. Check out what more to see and do in Expedia's Pythagorio guide.
What's the weather like in Pythagorio?
The hottest months are usually August and July with an average temp of 77°F, while the coldest months are January and February with an average of 55°F. Average annual precipitation for Pythagorio is 33 inches.