The Best Hotels Closest to Museum of Life and Science in Raleigh for 2026

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Our top choices for Museum of Life and Science hotels

A breakfast area with a chalkboard menu, a sign indicating breakfast starts here, and a variety of food items like waffles, oatmeal, and fruits.

A large indoor swimming pool with clear blue water, surrounded by beige tiled flooring and walls, with large windows allowing natural light.

A hotel room with a bed, a desk with a chair, a flat-screen TV, a microwave, and a mirror.

A Hampton Inn hotel with a modern facade, multiple floors, and a parking lot.

1. Hampton Inn & Suites Durham/North I-85

1.4 km from Museum of Life and Science

elizabeth

￥18,138

￥20,587 total

includes taxes & fees

Sep 27 - Sep 28

A hotel room with two beds, a flat-screen TV, a wooden headboard, and a carpeted floor.

A coffee station with two coffee machines, a coffee press, and various coffee-related items on a counter.

A gym with treadmills, elliptical machines, and a rack of dumbbells.

A Holiday Inn Express hotel with a modern design, featuring a prominent sign, multiple windows, and a well-lit entrance.

2. Holiday Inn Express Durham by IHG

2.2 km from Museum of Life and Science

Kimberly R

￥17,512

￥19,878 total

includes taxes & fees

Sep 23 - Sep 24

A hotel room with a bed, a desk, a chair, a small table, a coffee machine, and a trash bin.

A reception area with a wooden reception desk, blue seating, a flat-screen TV, and a stone accent wall.

A swimming pool with lounge chairs and umbrellas, surrounded by a building with a clear sky.

A Comfort Inn & Suites hotel with a modern design, featuring a prominent entrance and a landscaped front yard.

3. Comfort Inn & Suites Durham near Duke University

Croasdaile Farm Master, 3.2 km from Museum of Life and Science

Ngoc

￥12,986

￥14,740 total

includes taxes & fees

Oct 11 - Oct 12

A hotel room with two beds, a TV, a desk, and a chair.

A vending machine area with Pepsi and other beverage options, including a selection of juices and sodas.

A motel with a red and white sign, multiple balconies, and a parking lot.

A Red Roof Inn reception area with a stone wall, a coffee machine, and two white armchairs.

4. Red Roof Inn Durham - Duke Univ Medical Center

2.2 km from Museum of Life and Science

Luis

￥9,631

￥11,191 total

includes taxes & fees

Sep 21 - Sep 22

A stone fire pit surrounded by striped chairs and tables in an outdoor lounge area with a view of a building in the background.

A modern dining area with a long table, multiple chairs, and a sofa with red ottomans.

A modern hotel lobby with a reception desk, seating area, and a cityscape mural on the wall.

A Hampton Inn & Suites hotel with a modern facade, multiple windows, and a parking lot.

5. Hampton Inn & Suites Durham University Medical Center

4.8 km from Museum of Life and Science

Claire

￥18,846

￥21,390 total

includes taxes & fees

Sep 27 - Sep 28

A bar area with wooden bar stools, pendant lighting, and a counter with a glass display. There are tables and chairs in the background, and the room has a wooden floor.

A hotel room with two beds, a sofa, a TV, and a bathroom visible through a door.

A covered porch with steps leading to a door, a brick wall, and a street lamp.

A bar area with wooden shelves, a chalkboard menu, and various bottles.

6. The Colonial Inn, an Ascend Collection Hotel

18.9 km from Museum of Life and Science

Veronica

￥16,966

￥19,257 total

includes taxes & fees

Oct 11 - Oct 12

A brick pathway flanked by neatly trimmed hedges leading to a building with a red facade and a grey roof.

A modern living room with two sofas facing a glass coffee table, a large window with curtains, and a brick wall.

An outdoor dining area with tables set for four, surrounded by a brick pathway and lush greenery.

A restaurant with brick walls, wooden tables, and blue chairs.

7. Rizzo Center, a Destination by Hyatt Hotel

16.3 km from Museum of Life and Science

Andrea

￥30,261

￥34,346 total

includes taxes & fees

Sep 21 - Sep 22

A modern lobby with a central seating area, a TV screen, and a patterned wall.

A modern hotel room with a bed, bedside table, TV, and a small desk area.

A modern kitchen with a built-in refrigerator, a gray sofa, and a gray armchair.

A reception area with a counter, a welcome sign, a digital screen, and a hallway leading to a dining area.

8. Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek

17.5 km from Museum of Life and Science

Frank

￥18,214

￥20,626 total

includes taxes & fees

Sep 27 - Sep 28

A swimming pool with lounge chairs and a wooden fence.

A multi-story hotel with a modern design, featuring a prominent entrance with a glass canopy and an American flag.

A modern bar area with a refrigerated display, wooden bar counter, and seating.

A spacious lobby with a reception desk, seating area, and artwork on the walls.

9. Hyatt Place Durham Southpoint

15.3 km from Museum of Life and Science

Andres

￥20,737

￥23,537 total

includes taxes & fees

Sep 21 - Sep 22

A hotel entrance with a stone facade, large wooden doors, and a view into the interior.

A dining area with a chandelier, tables, chairs, and a Christmas tree.

A hotel with a stone lion statue, a covered entrance, and a landscaped garden.

An indoor swimming pool with clear blue water, surrounded by lounge chairs and potted plants.

10. Washington Duke Inn & Golf Club

5.9 km from Museum of Life and Science

Lowell

￥37,258

￥42,288 total

includes taxes & fees

Sep 23 - Sep 24

An outdoor seating area with sofas, chairs, and a fire pit, adjacent to a modern building with large windows.

A modern bar area with a long counter, multiple bar stools, and a large screen displaying a sports event.

A modern kitchen with a central island, bar stools, wooden cabinets, and pendant lighting.

A modern living room with a fireplace, seating area, and a pool table.

11. JB Duke Hotel

5.6 km from Museum of Life and Science

Derek

￥31,159

￥35,367 total

includes taxes & fees

Sep 20 - Sep 21

A lobby with a green sofa, yellow chairs, a coffee table with drinks, and a window with plants.

A Hilton Garden Inn hotel with a modern design, featuring a large entrance and a parking area with a delivery van.

An indoor swimming pool with clear glass walls, a tiled floor, and a seating area with chairs and a table.

A business center with wooden paneling, multiple workstations, and framed artwork on the walls.

12. Hilton Garden Inn Durham/University Medical Center

9th Street District, 3.3 km from Museum of Life and Science

Hal

￥22,641

￥25,698 total

includes taxes & fees

Sep 27 - Sep 28

An indoor swimming pool with clear water, a no diving sign, and a seating area with chairs and tables.

A modern kitchen with built-in shelves, a glass backsplash, and a variety of kitchenware.

A modern hotel lobby with a reception desk, several chairs, a large monitor, and pendant lighting.

A modern hotel lobby with a long dining table, multiple chairs, a sofa, and a bar area.

13. Hyatt House Raleigh / RDU / Brier Creek

17.1 km from Museum of Life and Science

William

￥18,202

￥20,613 total

includes taxes & fees

Sep 27 - Sep 28

A breakfast counter with various food items and a sign that reads 'TOP IT BREAKFAST'.

An outdoor seating area with a blue sofa, orange chairs, and a table.

A modern hotel lobby with a central counter, a refrigerated display case, and a seating area with a sofa.

14. Tru by Hilton Raleigh Durham Airport

19.7 km from Museum of Life and Science

Jennifer

￥16,317

￥18,479 total

includes taxes & fees

Oct 4 - Oct 5

An outdoor seating area with wicker chairs and a large umbrella, a fire feature, and a view of the interior through glass walls.

A hotel room with a large bed, a bedside table with a lamp, a TV mounted on the wall, and a window with curtains.

A kitchen with a microwave, coffee maker, and sink.

A modern kitchen with a microwave, coffee maker, and dishwasher. There is a round table with two green chairs in front.

15. DoubleTree Suites by Hilton Raleigh - Durham

13.3 km from Museum of Life and Science

Ryan

￥14,467

￥16,419 total

includes taxes & fees

Sep 27 - Sep 28

A modern hotel with a prominent entrance, multiple floors, and a balcony on the second floor.

A modern hotel room with a bed, a desk, a chair, a small seating area, and a kitchenette.

A modern dining area with wooden tables and chairs, large windows, and geometric pendant lighting.

A modern hotel lobby with a reception desk, a beverage refrigerator, and a well-stocked snack bar.

16. SpringHill Suites by Marriott Durham City View

4.6 km from Museum of Life and Science

Taurean

￥19,716

￥22,377 total

includes taxes & fees

Sep 27 - Sep 28

A spacious, elegantly decorated interior with a central round table, high ceilings, and classic architectural columns.

A large, historic building with a central courtyard, columns, and a brick facade.

A spacious living room with a sofa, armchairs, a coffee table, and a chandelier.

A well-lit living room with a sofa, armchairs, a coffee table, and a fireplace.

17. The Carolina Inn, a Destination by Hyatt Hotel

19.3 km from Museum of Life and Science

vasilisa

￥49,167

￥55,805 total

includes taxes & fees

Sep 20 - Sep 21

An outdoor patio with wicker furniture, a stone fire pit, and a brick building in the background.

A gym with treadmills, elliptical machines, a bench press, and a blue balance board.

A hotel room with two beds, a desk, a TV, and a sofa.

A spacious lobby with a reception desk, seating area, and a beverage kiosk.

18. Residence Inn Durham McPherson/Duke University Medical Cntr

Trinity Park, 3.3 km from Museum of Life and Science

Shelly

￥25,655

￥29,118 total

includes taxes & fees

Sep 20 - Sep 21

An outdoor patio with a stone fire pit, seating, and a covered area.

A modern dining area with wooden tables and chairs, a kitchen in the background, and a counter with stools.

A reception area with a wooden counter, a 'HELLO Morrisville' sign, a 'PINCH' sign above a snack display, and a 'Manager on Duty' sign.

A hotel room with a bed, a desk, and a chair. There is a door and a wall-mounted lamp.

19. Towneplace Suites By Marriott Raleigh-Durham Airport/Morrisville

19.7 km from Museum of Life and Science

Anthony

￥15,579

￥17,644 total

includes taxes & fees

Sep 20 - Sep 21

A spacious lobby with high ceilings, a central fountain, and seating areas.

A modern bedroom with a large bed, a fireplace, a walk-in closet, and a bathroom with a round mirror and vanity.

A spacious lobby with a curved seating area, large windows, and a modern chandelier.

A bar area with multiple liquor cabinets and hanging pendant lights.

20. Embassy Suites by Hilton Raleigh Durham Airport Brier Creek

17.5 km from Museum of Life and Science

Darren C.

￥24,436

￥27,674 total

includes taxes & fees

Sep 27 - Sep 28

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Compare popular hotels close to Museum of Life and Science

Property	Star rating	Guest rating
Hampton Inn & Suites Durham/North I-85	9.0 1001 1,001 reviews	View
Holiday Inn Express Durham by IHG	8.8 1002 1,002 reviews	View
Comfort Inn & Suites Durham near Duke University	8.6 1140 1,140 reviews	View
Red Roof Inn Durham - Duke Univ Medical Center	6.8 1002 1,002 reviews	View
Hampton Inn & Suites Durham University Medical Center	9.6 554 554 reviews	View

Top Museum of Life and Science Hotel Reviews

Holiday Inn Express Durham by IHG

10/10 Excellent

"Very clean rooms, easy access, breakfast, pool"

Unscripted Durham, Part of JDV by Hyatt

8/10 Good

"none at this time"

Curated & Caffeinated! Gem near Duke & Downtown • Espresso bar, Eco+, Fire Pit

10/10 Excellent

"Kristin was a wonderful host and we loved our stay! The house was so thoughtfully curated and comfortable. We would definitely stay here again if we visit Durham in the future!"

NEW! Renovated 2Br/1Ba Convenient to 9th St, NCSSM

10/10 Excellent

"this stay reminded me of a time when vacation rentals used to be clean and neat with thoughtful touches like extra blankets and a few extras of things you might have forgotten (toothpaste, coffee and tea); in other words, it was exactly that and i really appreciated it."

21c Museum Hotel Durham

10/10 Excellent

"This is a charmingly retro, art-centric hotel. Fun to stay at 21c."

Red Roof Inn Durham - Duke Univ Medical Center

8/10 Good

"The ID worked well. Seems kind of exposed to the outside but the curtain still worked well."

Everything within 1 mile

10/10 Excellent

"Perfect size and great location! The host has thought of everything and included so many extra thoughtful touches! So close to everything, quiet, clean, and stocked!"

Cottage with Yard, Mins to Duke

10/10 Excellent

"This was a cheerful home with comfortable beds and many thoughtful extras. We enjoyed our time here."

New & Renovated Charming Bungalow near DT Durham

10/10 Excellent

"quiet neighborhood and cozy home close to anything you’d need in durham. bed was comfy, shower was good, all is well!"

Other attractions near Museum of Life and Science

Brightleaf Square

9.6/10 (8 reviews)

You can browse for the perfect souvenirs at Brightleaf Square during your visit to Durham. Discover the lively festivals and stunning cathedral in this family-friendly area.

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Vietnam Veterans Living Memorial

You can find out about the history of Durham with a visit to Vietnam Veterans Living Memorial. Attend a sporting event or visit the stunning cathedral in this family-friendly area.

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Northgate Mall

8.2/10 (60 reviews)

You can find the perfect gifts to bring home at Northgate Mall during your trip to Durham. Experience the lively festivals or attend a sporting event in this family-friendly area.

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Duke Homestead

Learn about the local history of Durham when you take a trip to Duke Homestead. Attend a sporting event or visit the stunning cathedral in this family-friendly area.

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Fullsteam Brewery

7.4/10 (3 reviews)

You can take time to visit Fullsteam Brewery during your travels to Durham. Experience the lively festivals or attend a sporting event in this family-friendly area.

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Durham Convention Center

8.2/10 (118 reviews)

Learn about the events happening at Durham Convention Center during your trip to Durham. Discover the entertainment choices and stunning cathedral in this family-friendly area.

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African American Dance Ensemble

8.8/10 (3 reviews)

You can enjoy some culture when you stop by African American Dance Ensemble in Durham.

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Carolina Theatre

8.2/10 (220 reviews)

You can make plans for a show at Carolina Theatre during your stay in Durham. Experience the area's entertainment choices or attend a sporting event.

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Frequently asked questions

What's the area like around Museum of Life and Science?

Museum of Life and Science is located in an area of Durham known for its stunning cathedral. If you're looking for a convenient place to stay, check out the 10 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Museum of Life and Science?

Hampton Inn & Suites Durham/North I-85 is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located just a short 0.8 mi (1.4 km) from Museum of Life and Science. Other good options within 5 miles include Courtyard Durham Near Duke University/Downtown and Red Roof Inn Durham - Duke Univ Medical Center.

How many hotels will I find close to Museum of Life and Science?

Expedia has 10 hotels and other accommodations within a mile from Museum of Life and Science.

If I need to cancel the hotel reservation for my stay near Museum of Life and Science, will I receive a refund?

Yes, most hotel room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you booked a non-refundable reservation, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then use the "fully refundable" filter to view the best deals near Museum of Life and Science.

Where can I learn more about changing or cancelling my trip in the area near Museum of Life and Science?

To access more information about picking new dates or cancelling your stay near Museum of Life and Science, go to https://www.expedia.com/service/.

What can I see and do near Museum of Life and Science?

You'll want to browse the exhibits at Nasher Museum of Art at Duke University and Bennett Place. Explore landmarks like American Tobacco Campus, Cameron Indoor Stadium, and Wallace Wade Stadium. You can enjoy live performances at Carolina Theatre and Common Ground Theatre.

Find hotels near Museum of Life and Science, Raleigh from ￥11,191

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Our top choices for Museum of Life and Science hotels

1. Hampton Inn & Suites Durham/North I-85

2. Holiday Inn Express Durham by IHG

3. Comfort Inn & Suites Durham near Duke University

4. Red Roof Inn Durham - Duke Univ Medical Center

5. Hampton Inn & Suites Durham University Medical Center

6. The Colonial Inn, an Ascend Collection Hotel

7. Rizzo Center, a Destination by Hyatt Hotel

8. Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek

9. Hyatt Place Durham Southpoint

10. Washington Duke Inn & Golf Club

11. JB Duke Hotel

12. Hilton Garden Inn Durham/University Medical Center

13. Hyatt House Raleigh / RDU / Brier Creek

14. Tru by Hilton Raleigh Durham Airport

15. DoubleTree Suites by Hilton Raleigh - Durham

16. SpringHill Suites by Marriott Durham City View

17. The Carolina Inn, a Destination by Hyatt Hotel

18. Residence Inn Durham McPherson/Duke University Medical Cntr

19. Towneplace Suites By Marriott Raleigh-Durham Airport/Morrisville

20. Embassy Suites by Hilton Raleigh Durham Airport Brier Creek

Compare popular hotels close to Museum of Life and Science

Top Museum of Life and Science Hotel Reviews

Holiday Inn Express Durham by IHG

Unscripted Durham, Part of JDV by Hyatt

Curated & Caffeinated! Gem near Duke & Downtown • Espresso bar, Eco+, Fire Pit

NEW! Renovated 2Br/1Ba Convenient to 9th St, NCSSM

21c Museum Hotel Durham

Red Roof Inn Durham - Duke Univ Medical Center

Everything within 1 mile

Cottage with Yard, Mins to Duke

*New & Renovated* Charming Bungalow near DT Durham

Other attractions near Museum of Life and Science

Brightleaf Square

Vietnam Veterans Living Memorial

Northgate Mall

Duke Homestead

Fullsteam Brewery

Durham Convention Center

African American Dance Ensemble

Carolina Theatre

Frequently asked questions

New & Renovated Charming Bungalow near DT Durham