The Best Hotels Closest to Museum of Life and Science in Raleigh for 2026

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Our top choices for Museum of Life and Science hotels

1. Hampton Inn & Suites Durham/North I-85

1.4 km from Museum of Life and Science

Rebecca

￥21,859 total

includes taxes & fees

Aug 16 - Aug 17

2. Holiday Inn Express Durham by IHG

2.2 km from Museum of Life and Science

Ignacio

￥27,398 total

includes taxes & fees

Aug 12 - Aug 13

Suite, 1 King Bed with Sofa bed, Non Smoking | Premium bedding, desk, blackout drapes, iron/ironing board

3. Comfort Inn & Suites Durham near Duke University

Croasdaile Farm Master, 3.2 km from Museum of Life and Science

LILIANA

￥17,886 total

includes taxes & fees

Aug 23 - Aug 24

4. Red Roof Inn Durham - Duke Univ Medical Center

2.2 km from Museum of Life and Science

Derrick

￥11,357 total

includes taxes & fees

Aug 12 - Aug 13

5. Hampton Inn & Suites Durham University Medical Center

4.8 km from Museum of Life and Science

Regina

￥24,136 total

includes taxes & fees

Jul 30 - Jul 31

6. The Colonial Inn, an Ascend Collection Hotel

18.9 km from Museum of Life and Science

Sharon

￥22,127 total

includes taxes & fees

Aug 9 - Aug 10

7. Rizzo Center, a Destination by Hyatt Hotel

16.3 km from Museum of Life and Science

mehmet

￥34,434 total

includes taxes & fees

Jul 31 - Aug 1

8. Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek

17.5 km from Museum of Life and Science

STEVEN

￥21,812 total

includes taxes & fees

Aug 16 - Aug 17

9. The Westin Raleigh-Durham Airport

17.5 km from Museum of Life and Science

Lucian

￥42,307 total

includes taxes & fees

Aug 8 - Aug 9

10. Fairfield by Marriott Inn & Suites Durham

17.3 km from Museum of Life and Science

Richard

￥19,154 total

includes taxes & fees

Jul 30 - Jul 31

11. Hyatt Place Durham Southpoint

15.3 km from Museum of Life and Science

Sam

￥23,617 total

includes taxes & fees

Aug 20 - Aug 21

12. JB Duke Hotel

5.6 km from Museum of Life and Science

Sophia

￥35,149 total

includes taxes & fees

Aug 2 - Aug 3

13. Washington Duke Inn & Golf Club

5.9 km from Museum of Life and Science

Kyna

￥38,784 total

includes taxes & fees

Aug 23 - Aug 24

Daily cooked-to-order breakfast for a fee

14. Courtyard Raleigh-Durham Airport/Brier Creek

15.9 km from Museum of Life and Science

Peggy

￥22,336 total

includes taxes & fees

Jul 31 - Aug 1

15. Tru by Hilton Raleigh Durham Airport

19.7 km from Museum of Life and Science

Rajani

￥19,629 total

includes taxes & fees

Aug 8 - Aug 9

16. Embassy Suites by Hilton Raleigh Durham Airport Brier Creek

17.5 km from Museum of Life and Science

Brian

￥29,519 total

includes taxes & fees

Aug 9 - Aug 10

17. The Carolina Inn, a Destination by Hyatt Hotel

19.3 km from Museum of Life and Science

Kelli

￥60,997 total

includes taxes & fees

Aug 20 - Aug 21

18. Hyatt House Raleigh / RDU / Brier Creek

17.1 km from Museum of Life and Science

Darius

￥23,394 total

includes taxes & fees

Aug 13 - Aug 14

19. Residence Inn Raleigh-Durham Airport/Brier Creek

15.9 km from Museum of Life and Science

Leslie

￥24,179 total

includes taxes & fees

Aug 1 - Aug 2

20. Towneplace Suites By Marriott Raleigh-Durham Airport/Morrisville

19.7 km from Museum of Life and Science

Mark

￥19,394 total

includes taxes & fees

Aug 16 - Aug 17

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Compare popular hotels close to Museum of Life and Science

Property	Star rating	Guest rating
Hampton Inn & Suites Durham/North I-85	2.5 star property	9.0 Wonderful 1,004 reviews	View
Holiday Inn Express Durham by IHG	2.5 star property	8.8 Excellent 1,007 reviews	View
Comfort Inn & Suites Durham near Duke University	2.5 star property	8.6 Excellent 1,082 reviews	View
Red Roof Inn Durham - Duke Univ Medical Center	2.0 star property	6.8 1,001 reviews	View
Hampton Inn & Suites Durham University Medical Center	2.5 star property	9.6 Exceptional 523 reviews	View

Top Museum of Life and Science Hotel Reviews

Hampton Inn & Suites Durham/North I-85

10/10 Excellent

"The staff were very friendly and helpful. The room was nice and clean and the bed was comfortable."

Curated & Caffeinated! Gem near Duke & Downtown • Espresso bar, Eco+, Fire Pit

10/10 Excellent

"It was the perfect spot to spend a few nights while we visited colleges in the area. The cottage was very clean and well decorated with pleasant details in every room (white noise maker, nightlight/ceiling projector, cotton balls, cosmetic wedges, welcome basket with snacks and treats, linen spray). The coffee and tea station was incredible. The whole experience was top notch and will truly spoil us when we rent anywhere else in the future."

Guest House with private Gate Near Downtown Durham Peaceful 2-bedroom 2 Bathroom

10/10 Excellent

"We enjoyed our short stay at Alexis's guest house. It's conveniently located and easy to find. Alexis was a wonderful host and so gracious. If we ever need to stay in Durham again we will definitely stay at his guest house."

Durham Charm Near Duke & 9Th St

8/10 Good

"It wasn’t as cool as we would’ve liked it. There are portable AC units in the living room and window units in the bedrooms. The living room and kitchen did not get very cool but luckily we were mostly there in the evenings. Unfortunately the backyard is completely overgrown so there’s no hanging out or taking dogs back there (if you’re traveling with one). Otherwise the property was clean and convenient for us going to my sister’s wedding."

Other attractions near Museum of Life and Science

Brightleaf Square

9.6/10 (8 reviews)

You can browse for the perfect souvenirs at Brightleaf Square during your visit to Durham. Discover the lively festivals and stunning cathedral in this family-friendly area.

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Frequently asked questions

What's the area like around Museum of Life and Science?

Museum of Life and Science is located in an area of Durham known for its stunning cathedral. If you're looking for a convenient place to stay, check out the 11 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Museum of Life and Science?

Hampton Inn & Suites Durham/North I-85 is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located just a short 0.8 mi (1.4 km) from Museum of Life and Science. Other good options within 5 miles include Comfort Inn & Suites Durham near Duke University and Holiday Inn Express Durham by IHG.

How many hotels will I find close to Museum of Life and Science?

Expedia has 11 hotels and other accommodations within a mile from Museum of Life and Science.

If I need to cancel the hotel reservation for my stay near Museum of Life and Science, will I receive a refund?

Yes, most hotel room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you booked a non-refundable reservation, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then use the "fully refundable" filter to view the best deals near Museum of Life and Science.

Where can I learn more about changing or cancelling my trip in the area near Museum of Life and Science?

To access more information about picking new dates or cancelling your stay near Museum of Life and Science, go to https://www.expedia.com/service/.

What can I see and do near Museum of Life and Science?

You'll want to browse the exhibits at Nasher Museum of Art at Duke University and Bennett Place. Explore landmarks like American Tobacco Campus, Cameron Indoor Stadium, and Wallace Wade Stadium. You can enjoy live performances at Carolina Theatre and Common Ground Theatre.

Find hotels near Museum of Life and Science, Raleigh from ￥11,357

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Our top choices for Museum of Life and Science hotels

1. Hampton Inn & Suites Durham/North I-85

2. Holiday Inn Express Durham by IHG

3. Comfort Inn & Suites Durham near Duke University

4. Red Roof Inn Durham - Duke Univ Medical Center

5. Hampton Inn & Suites Durham University Medical Center

6. The Colonial Inn, an Ascend Collection Hotel

7. Rizzo Center, a Destination by Hyatt Hotel

8. Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek

9. The Westin Raleigh-Durham Airport

10. Fairfield by Marriott Inn & Suites Durham

11. Hyatt Place Durham Southpoint

12. JB Duke Hotel

13. Washington Duke Inn & Golf Club

14. Courtyard Raleigh-Durham Airport/Brier Creek

15. Tru by Hilton Raleigh Durham Airport

16. Embassy Suites by Hilton Raleigh Durham Airport Brier Creek

17. The Carolina Inn, a Destination by Hyatt Hotel

18. Hyatt House Raleigh / RDU / Brier Creek

19. Residence Inn Raleigh-Durham Airport/Brier Creek

20. Towneplace Suites By Marriott Raleigh-Durham Airport/Morrisville

Compare popular hotels close to Museum of Life and Science

Top Museum of Life and Science Hotel Reviews

Hampton Inn & Suites Durham/North I-85

Other attractions near Museum of Life and Science

Brightleaf Square

Frequently asked questions