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Compare 340 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

ARIQUEPAY HOTEL

4.0 star property
Historical Center
9.6 out of 10, Exceptional, (176)
"The room was spotless, breakfast was pretty good, good location, rooftop bar is really nice. Only reason why it is not rated excellent is because the property is very noisy/loud."
United States
Emily
ARIQUEPAY HOTEL

Hotel Boutique Villa Elisa

3.5 star property
Historical Center
9.8 out of 10, Exceptional, (131)
"Loved this place. Don’t even want to think how much place like this would cost in the States."
United States
Ros
The price is ¥11,055
¥11,055 total
Dec 4 - Dec 5
Hotel Boutique Villa Elisa

qp Hotels Arequipa

3.5 star property
Historical Center
8.8 out of 10, Excellent, (151)
"The hotel is within a few minutes walk of the main square. Room size was good and having facilities to make hot drinks and have a fridge in the room was brilliant."
United Kingdom
Alexis
The price is ¥13,734
¥13,734 total
Dec 3 - Dec 4
qp Hotels Arequipa

Casa Andina Premium Arequipa

4.0 star property
Historical Center
9.2 out of 10, Wonderful, (385)
"Great place. 2 blocks from Plaza de Armas. Clean, great food, great staff."
United States
Kat Lim
The price is ¥18,626
¥20,489 total
Jan 2 - Jan 3, 2026
Casa Andina Premium Arequipa

Las Torres de Ugarte

3.0 star property
Historical Center
9.0 out of 10, Wonderful, (231)
"Great place very accommodating love the customer service "
United States
Yuvitkza
The price is ¥10,500
¥10,500 total
Jan 1 - Jan 2, 2026
Las Torres de Ugarte

CIRQA - Relais & Châteaux

3.5 star property
Historical Center
9.6 out of 10, Exceptional, (31)
"A great and unique place to stay in Arequipa"
United States
Min
The price is ¥64,323
¥70,827 total
Dec 14 - Dec 15
CIRQA - Relais & Châteaux

QASA Arequipa by Nomad

3.5 star property
Historical Center
9.4 out of 10, Exceptional, (91)
"The staff there were WONDERFUL!"
United States
Shinthia
The price is ¥9,582
¥10,562 total
Dec 4 - Dec 5
QASA Arequipa by Nomad

ANDARI HOTELES

3.0 star property
Historical Center
10.0 out of 10, Exceptional, (1)
"La habitación estaba muy limpia y ordenada , y el personal fue muy amable y atento. Es cercano a la plaza de armas de la ciudad, me gustó, definitivamente volveré."
United States
alexander
The price is ¥8,629
¥8,629 total
Dec 3 - Dec 4
ANDARI HOTELES

Palla Boutique Hotel

3.5 star property
Historical Center
9.4 out of 10, Exceptional, (113)
"Brilliant stay in a great hotel"
Australia
Rosanna
The price is ¥12,880
¥14,168 total
Dec 26 - Dec 27
Palla Boutique Hotel

HOTEL AREQUIPA INN

3.0 star property
Historical Center
9.6 out of 10, Exceptional, (70)
"The staff excellent, the breakfast superb"
United States
DORA
The price is ¥5,488
¥5,488 total
Dec 4 - Dec 5
HOTEL AREQUIPA INN

INKALMA CENTRO

2.0 star property
Historical Center
9.6 out of 10, Exceptional, (7)
"I can't fault this hotel. I arrived at 5am after a 14 hour bus journey and even though my check in wasn't until 12 they found me a room and I was asleep by 6. All at no extra cost I've never felt so welcome. Lovely staff, clean and quiet hotel and really convenient for the centre of town. Zero complaints."
United Kingdom
Gareth
The price is ¥4,536
¥5,780 total
Dec 17 - Dec 18
INKALMA CENTRO

Hostal Villa Sillar

3.0 star property
Historical Center
9.0 out of 10, Wonderful, (66)
"It was a great place to stay in Arequipa"
Canada
ROCIO
The price is ¥12,192
¥12,192 total
Dec 31 - Jan 1, 2026
Hostal Villa Sillar

La Casa de Margott

2.5 star property
Historical Center
9.0 out of 10, Wonderful, (23)
"Good place to stay, nearby the main plaza of arequipa, "
United States
Anonymous traveler
The price is ¥6,222
¥6,222 total
Dec 7 - Dec 8
La Casa de Margott

DM Hoteles Arequipa

3.0 star property
Cerro Colorado District
7.2 out of 10, Good, (5)
" Para ser un Hotel de una cadena importante fue muy decepcionante que alguno de su personal no sea servicial y perdida en dar información de los servicios esto me toco vivir con la recepcionista. Los precios que se pagan no están de acuerdo a la calidad de servicio. "
Peru
lino
DM Hoteles Arequipa

Mint Hotel

3.5 star property
Historical Center
9.2 out of 10, Wonderful, (128)
"Great place to stay "
United States
JOHN
Mint Hotel

El Portal de San Lázaro

3.0 star property
Historical Center
9.2 out of 10, Wonderful, (33)
"One night stay on the way to colca canyon. Hotel is in historic centre, 10min walk to plasa the armas. Even closer are some bars and restaurants with good music and food. Room was small but clean, breakfast excellent, staff helpful and pleasant. Perfect for several nights in arequipa. Recommended. a"
European Union
Goran
The price is ¥5,644
¥5,644 total
Dec 7 - Dec 8
El Portal de San Lázaro

Hampton by Hilton Arequipa

4.0 star property
Historical Center
9.4 out of 10, Exceptional, (108)
"We stayed here for 4 nights and loved everything about this location! We loved the staff and how comfortable the rooms were. Overall would recommend and would definitely stay here again! "
Canada
Anchal
The price is ¥15,556
¥17,112 total
Dec 12 - Dec 13
Hampton by Hilton Arequipa

Tierra Viva Arequipa Plaza

3.0 star property
Historical Center
9.4 out of 10, Exceptional, (452)
"Nice place to stay"
Mexico
Jose
Tierra Viva Arequipa Plaza

qema Arequipa

3.0 star property
Historical Center
9.6 out of 10, Exceptional, (34)
"Really cool place to stay. The gardens and pool were really nice to chill out in."
United Kingdom
Emma
The price is ¥3,279
¥3,607 total
Dec 16 - Dec 17
qema Arequipa

HUB HOTELS

3.0 star property
Arequipa
10.0 out of 10, Exceptional, (2)
"The room and bathroom were spotless. The staff make a great breakfast, were also very friendly and even lent me a phone charger for a couple of hours. The area is safe, walkable and there are some stores and restaurants nearby. "
United States
Joel
The price is ¥8,224
¥8,224 total
Jan 2 - Jan 3, 2026
HUB HOTELS
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mosopuquio Hotel Reviews

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Frequently asked questions

Where is the best place for a stay in Mosopuquio?
Located 12.4 mi (19.9 km) from the heart of Mosopuquio, qema Arequipa is a top choice for your stay based on our traveler data. Other good choices for your stay in the area are Sonesta Hotel Arequipa and Wyndham Costa del Sol Arequipa. See all available top hotels, or vacation rentals in Mosopuquio.
What are some of the best vacation home rentals that Mosopuquio has to offer?
Amazing Views of Misti in Yanahuara: This vacation home rental near Mosopuquio is located in the historical district and has a patio, a rooftop terrace, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave. Kick off your shoes and enjoy yourself with a selection of games and a hot tub. See all vacation rentals in Mosopuquio.
If I need to cancel my hotel reservation in Mosopuquio, will I receive a refund?
Yes, most room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Mosopuquio.
Where can I learn more about changing or cancelling my trip to Mosopuquio?
To find more details about changing or cancelling your trip to Mosopuquio, go to https://www.expedia.com/service/.
What's it like to stay in Mosopuquio?
Those traveling to Mosopuquio are sure to enjoy the sights to see and things to do. There are 340 hotels and other accommodations in the surrounding area. Find out more about Mosopuquio.
What is there to see in Mosopuquio?
Places to visit in the wider area include Molino de Sabandia, Mall Aventura Porongoche, and El Misti. You'll also find Parque Lambramani and Arequipa Stadium in the area. Check out what more to see and do in Expedia's Mosopuquio guide.
What's the seasonal weather like in Mosopuquio?
The hottest months are usually September and October with an average temp of 58°F, while the coldest months are July and June with an average of 56°F. Average annual precipitation for Mosopuquio is 14 inches.

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