Default HTG hotel image

Find hotels in Mesopotamia from ￥8,542

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Jul 17 - Jul 19
Next weekend
Jul 24 - Jul 26

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Mesopotamia hotels

Interior

To Spiti tis Sofias

To Spiti tis Sofias
Kastoria
10.0 out of 10, Exceptional, (1 review)
"Tout simplement le meilleur de notre voyage en Grèce. Simple mais tellement mieux qu'ailleurs. Accueil parfait, chambre confortable et petit déjeuner de roi. Je reviendrais à 100% si je passe dans le coin. "
France
Anonymous traveler
The price is ￥9,729
￥11,419 total
includes taxes & fees
Jul 26 - Jul 27
To Spiti tis Sofias
Front of property - evening/night

Hotel Anastassiou

Hotel Anastassiou
2.0 star property
Kastoria
8.0 out of 10, Very Good, (70 reviews)
"Nice simple stay."
United States
Jeffrey
The price is ￥7,195
￥8,542 total
includes taxes & fees
Aug 14 - Aug 15
Hotel Anastassiou
Property grounds

Anesis Hotel

Anesis Hotel
2.0 star property
Kastoria
9.0 out of 10, Wonderful, (9 reviews)
"Fantastic hotel in the heart of Kastoria. The owners are lovely people, very helpful and made me feel right at home. Will definitely stay there again!"
Canada
Adam
The price is ￥8,506
￥10,029 total
includes taxes & fees
Jul 27 - Jul 28
Anesis Hotel
Lunch and dinner served

Guesthouse Monopati

Guesthouse Monopati
Amyntaio
10.0 out of 10, Exceptional, (3 reviews)
The price is ￥11,466
￥13,392 total
includes taxes & fees
Jul 23 - Jul 24
Guesthouse Monopati
Exterior

Guest House Ilektra

Guest House Ilektra
Voio
9.8 out of 10, Exceptional, (11 reviews)
"Friendly and courteous hosts, great food and excellent service "
United States
Pantelia
The price is ￥9,767
￥11,461 total
includes taxes & fees
Jul 28 - Jul 29
Guest House Ilektra
Terrace/patio

Chloe Hotel

Chloe Hotel
3.0 star property
Kastoria
10.0 out of 10, Exceptional, (88 reviews)
"Exceptional service, clean environment, superb breakfast and attentive staff."
United States
Tammy
The price is ￥17,093
￥20,336 total
includes taxes & fees
Jul 20 - Jul 21
Chloe Hotel
House | 2 bedrooms

Anastasia s Kastoria Cozy Modern Garden Retreat

Anastasia s Kastoria Cozy Modern Garden Retreat
Kastoria
Anastasia s Kastoria Cozy Modern Garden Retreat
Property grounds

Calma Hotel & Spa

Calma Hotel & Spa
4.0 star property
Kastoria
9.6 out of 10, Exceptional, (37 reviews)
"Pleasant stay. Good amenities. Great staff. "
New Zealand
Robert
The price is ￥16,226
￥20,280 total
includes taxes & fees
Jul 26 - Jul 27
Calma Hotel & Spa
Restaurant

Guesthouse Vissinokipos

Guesthouse Vissinokipos
Kastoria
9.4 out of 10, Exceptional, (10 reviews)
"Wonderfull view and very friendly people.the place is avery dpecial artistic decorated.wonderfull weather.nice varieties for breakfast.price was ver good.i recommend it!"
United States
Carmen
The price is ￥10,573
￥12,377 total
includes taxes & fees
Jul 18 - Jul 19
Guesthouse Vissinokipos
Exterior

Arhontiko Christodoulou

Arhontiko Christodoulou
2.0 star property
Prespes
The price is ￥11,721
￥13,681 total
includes taxes & fees
Jul 18 - Jul 19
Arhontiko Christodoulou
Outdoor dining

OIKOI - Luxury Suites & Maisonettes

OIKOI - Luxury Suites & Maisonettes
Kastoria
The price is ￥16,116
￥22,369 total
includes taxes & fees
Aug 8 - Aug 9
OIKOI - Luxury Suites & Maisonettes
Exterior

Le Marron

Le Marron
4.0 star property
Voio
8.0 out of 10, Very Good, (1 review)
The price is ￥19,526
￥24,028 total
includes taxes & fees
Jul 16 - Jul 17
Le Marron
Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds

Kyknos De Luxe Hotel

Kyknos De Luxe Hotel
Kastoria
10.0 out of 10, Exceptional, (43 reviews)
"Very nice clean, very polite staff and great breakfast!"
United States
Vasilios
The price is ￥14,326
￥16,640 total
includes taxes & fees
Jul 30 - Jul 31
Kyknos De Luxe Hotel
Indoor pool

Esperos Palace Luxury & Spa Hotel

Esperos Palace Luxury & Spa Hotel
4.0 star property
Kastoria
9.0 out of 10, Wonderful, (84 reviews)
"The hotel is beautiful, large room with balcony. Grate bathroom, comfortable, the dinner is good ,however the breakfast was amazing. "
United States
Michal
The price is ￥19,068
￥23,504 total
includes taxes & fees
Jul 21 - Jul 22
Esperos Palace Luxury & Spa Hotel
Exterior

Andromeda Boutique hotel

Andromeda Boutique hotel
4.0 star property
Kastoria
8.8 out of 10, Excellent, (3 reviews)
The price is ￥10,279
￥15,379 total
includes taxes & fees
Jul 19 - Jul 20
Andromeda Boutique hotel
Apartment | Interior

Lūma Retreat

Lūma Retreat
Kastoria
The price is ￥11,866
￥13,846 total
includes taxes & fees
Jul 16 - Jul 17
Lūma Retreat
House | 3 bedrooms, high-speed internet

The Sunset Haven Kastoria Modern Lake Elegance

The Sunset Haven Kastoria Modern Lake Elegance
Kastoria
The price is ￥7,976
￥33,363 total
includes taxes & fees
Jul 17 - Jul 18
The Sunset Haven Kastoria Modern Lake Elegance
Terrace/patio

Orologopoulos Mansion

Orologopoulos Mansion
5.0 star property
Kastoria
9.6 out of 10, Exceptional, (36 reviews)
"Wonderful stay Very well kept hotel Nice room with a warm feeling The spaces in hotel are beautiful and give you the feeling that you stay at a luxurious home Very good breakfast- I will definitely stay here again "
United Kingdom
elyahu
The price is ￥19,634
￥25,071 total
includes taxes & fees
Aug 9 - Aug 10
Orologopoulos Mansion
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Mesopotamia Hotel Reviews

Limneon Resort & Spa

Limneon Resort & Spa

10/10 Excellent
"We had only a one night stay but it was lovely. Outdoor pool and breakfast were nice, bed is comfortable. The indoor pool and sauna area really need updating. But they are usable."
Brian 1-night trip
Posted 3 weeks ago
Limneon Resort & Spa

More cheap stays in Mesopotamia

Hotel Anastassiou

Hotel Anastassiou

1st km Highway Kastoria-Athens Kastoria Western Macedonia
The price is ￥7,195 per night from Aug 14 to Aug 15
￥7,195
￥8,542 total
Aug 14 - Aug 15
includes taxes & fees

Frequently asked questions

Where is the best place for a stay in Mesopotamia?
To Spiti tis Sofias is one of the top choices for your stay based on our traveler data. This guesthouse offers free parking and free WiFi. Two other choices for your visit to the area are Limneon Resort & Spa and Calma Hotel & Spa. See all available top hotels, or vacation rentals in Mesopotamia.
What are some of the best vacation home rentals that Mesopotamia has to offer?
Anastasia s Kastoria Cozy Modern Garden Retreat: This vacation home rental outside of Mesopotamia offers a garden, a barbecue grill, and free WiFi to help you feel perfectly comfortable in your new surroundings. This vacation rental also comes with free parking to give you added peace of mind. See all vacation rentals in Mesopotamia.
If I need to cancel my hotel reservation in Mesopotamia, will I receive a refund?
Yes! You'll find that most room reservations are refundable provided that you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Mesopotamia.
Where can I learn more about changing or cancelling my trip to Mesopotamia?
For more details about picking new dates or cancelling your trip to Mesopotamia, click here.
What is the best accommodation for staying close to Macedonia Airport (SKG)?
Hyatt Regency Thessaloniki is a popular 5-star hotel featuring 2 outdoor pools and a full-service spa. It's located a short 1.1 mi (1.8 km) from Macedonia Airport. Other options near the airport are Athina Airport Hotel and Hotel Nikopolis.
What is staying in Mesopotamia like?
Travelers to Mesopotamia will find plenty to explore and enjoy. There are 49 hotels and other accommodations in the surrounding area. Find out more about Mesopotamia.
What are the top places to visit in Mesopotamia?
Places to visit in the wider area include Neolithic Lakeside Settlement, Kastoria Lake, and Kastoria Aquarium. You'll also find Taxiarhia of the Metropolis and Dragon's Lair in the area. Check out what more to see and do in Expedia's Mesopotamia guide.
What's the seasonal weather like in Mesopotamia?
The hottest months are usually August and July with an average temp of 69°F, while the coldest months are January and February with an average of 37°F. Average annual precipitation for Mesopotamia is 28 inches.

Explore a world of travel with Expedia