Find hotels in Medical District, Huntsville

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Dec 25 - Dec 26
Tomorrow
Dec 26 - Dec 27
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Medical District hotels

Desk, laptop workspace, iron/ironing board, free WiFi
Hyatt Studios Huntsville

Hyatt Studios Huntsville

Hyatt Studios Huntsville
2.5 star property
10.2 km from Medical District
10.0 out of 10, Exceptional, (7)
"New facilities, very clean. Staff was very nice "
United States
Jake
The price is ￥14,447
￥16,927 total
includes taxes & fees
Dec 26 - Dec 27
Hyatt Studios Huntsville
Exterior
Hotel O Haven Inn Huntsville AL US 72

Hotel O Haven Inn Huntsville AL US 72

Hotel O Haven Inn Huntsville AL US 72
2.5 star property
3.4 km from Medical District
8.6 out of 10, Excellent, (31)
"Great place to stay"
United States
Wade
The price is ￥8,489
￥11,009 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Hotel O Haven Inn Huntsville AL US 72
Free daily buffet breakfast
Tru By Hilton Huntsville Research Park Area

Tru By Hilton Huntsville Research Park Area

Tru By Hilton Huntsville Research Park Area
2.5 star property
9.3 km from Medical District
8.4 out of 10, Very Good, (8)
"Everything was just great!!"
United States
Dominique
The price is ￥13,938
￥16,340 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Tru By Hilton Huntsville Research Park Area
Breakfast, lunch and dinner served
Four Points by Sheraton Huntsville Airport

Four Points by Sheraton Huntsville Airport

Four Points by Sheraton Huntsville Airport
3.0 star property
19.7 km from Medical District
8.6 out of 10, Excellent, (1002)
"The staff were very helpful and the room was clean!!!"
United States
Marietta
The price is ￥15,298
￥17,905 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Four Points by Sheraton Huntsville Airport
Lobby
Sleep Inn & Suites Huntsville near U.S. Space & Rocket Center

Sleep Inn & Suites Huntsville near U.S. Space & Rocket Center

Sleep Inn & Suites Huntsville near U.S. Space & Rocket Center
2.5 star property
6.8 km from Medical District
9.0 out of 10, Wonderful, (1001)
"The staff was really excellent into catering our needs for what we wanted during breakfast hours."
United States
George
The price is ￥13,894
￥16,291 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Sleep Inn & Suites Huntsville near U.S. Space & Rocket Center
View from property
Fairfield Inn & Suites by Marriott Huntsville Redstone Gateway

Fairfield Inn & Suites by Marriott Huntsville Redstone Gateway

Fairfield Inn & Suites by Marriott Huntsville Redstone Gateway
2.5 star property
9 km from Medical District
9.6 out of 10, Exceptional, (111)
"Nice hotel and good location"
United States
Mario
The price is ￥17,153
￥20,038 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Fairfield Inn & Suites by Marriott Huntsville Redstone Gateway
Reception
Hampton Inn & Suites Huntsville Hampton Cove

Hampton Inn & Suites Huntsville Hampton Cove

Hampton Inn & Suites Huntsville Hampton Cove
2.5 star property
9.6 km from Medical District
8.8 out of 10, Excellent, (1001)
"The hotel was nice"
United States
Shelby
The price is ￥14,705
￥17,223 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Hampton Inn & Suites Huntsville Hampton Cove
Lounge
Trilogy Hotel Huntsville, Autograph Collection

Trilogy Hotel Huntsville, Autograph Collection

Trilogy Hotel Huntsville, Autograph Collection
4.0 star property
1.2 km from Medical District
9.0 out of 10, Wonderful, (7)
"Arrogant...Worst Hotel experience I've ever had. Did not honor my reservation even though it was ALREADY paid for on Thanksgiving night. Unfriendly Front desk agent who obviously wasn't trained properly in customer service, argued with me for 40 plus minutes. Hotel was less than 1/2 full. Said I needed to pay again for a room I already paid for...?..... what? Condescending, patronizing, snobbish and disdainful attitude is what they were serving here for Thanksgiving."
United States
Robert
The price is ￥26,354
￥30,619 total
includes taxes & fees
Dec 30 - Dec 31
Trilogy Hotel Huntsville, Autograph Collection
In-room safe, desk, blackout drapes, iron/ironing board
Drury Inn & Suites Huntsville at the Space & Rocket Center

Drury Inn & Suites Huntsville at the Space & Rocket Center

Drury Inn & Suites Huntsville at the Space & Rocket Center
3.0 star property
6.8 km from Medical District
9.6 out of 10, Exceptional, (1000)
"Staff very friendly and attentive, great room, great value with the hospitality hours bfast, dinner, comp drinks for happy hour"
United States
Virginia
The price is ￥18,867
￥22,009 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Drury Inn & Suites Huntsville at the Space & Rocket Center
Free daily continental breakfast
avid hotel Madison - Huntsville West by IHG

avid hotel Madison - Huntsville West by IHG

avid hotel Madison - Huntsville West by IHG
2.5 star property
16.7 km from Medical District
8.8 out of 10, Excellent, (378)
"Great place"
United States
Terry
The price is ￥11,540
￥13,583 total
includes taxes & fees
Dec 28 - Dec 29
avid hotel Madison - Huntsville West by IHG
Exterior
Holiday Inn Express Hotel & Suites Huntsville West - Research Pk by IHG

Holiday Inn Express Hotel & Suites Huntsville West - Research Pk by IHG

Holiday Inn Express Hotel & Suites Huntsville West - Research Pk by IHG
2.5 star property
13.1 km from Medical District
9.6 out of 10, Exceptional, (882)
"Extremely friendly staff, easy checking in & out Very clean, room was comfortable, breakfast staff very helpful and breakfast hot and fresh . Highly recommend "
United States
TINA
The price is ￥13,879
￥16,273 total
includes taxes & fees
Dec 28 - Dec 29
Holiday Inn Express Hotel & Suites Huntsville West - Research Pk by IHG
Seasonal outdoor pool, open 8:00 AM to 9:00 PM, sun loungers
Clarion Pointe Madison Huntsville

Clarion Pointe Madison Huntsville

Clarion Pointe Madison Huntsville
2.5 star property
17 km from Medical District
8.6 out of 10, Excellent, (369)
"Room was spotless. Breakfast was nice…..staff polite and friendly. Would stay here again!"
United States
Colleen
The price is ￥11,797
￥13,878 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Clarion Pointe Madison Huntsville
Bar (on property)
Huntsville Marriott at the Space & Rocket Center

Huntsville Marriott at the Space & Rocket Center

Huntsville Marriott at the Space & Rocket Center
3.5 star property
6.6 km from Medical District
8.2 out of 10, Very Good, (835)
"Check in was easy and the room is great. "
United States
Anthony
The price is ￥17,153
￥20,219 total
includes taxes & fees
Dec 28 - Dec 29
Huntsville Marriott at the Space & Rocket Center
Breakfast, lunch and dinner served
106 Jefferson Huntsville, Curio Collection by Hilton

106 Jefferson Huntsville, Curio Collection by Hilton

106 Jefferson Huntsville, Curio Collection by Hilton
4.0 star property
Quigley, 1.3 km from Medical District
9.4 out of 10, Exceptional, (346)
"Very clean and convenient! Great smell coming inti the lobby and very friendly staff. "
United States
Bridget
The price is ￥22,923
￥26,673 total
includes taxes & fees
Jan 4 - Jan 5, 2026
106 Jefferson Huntsville, Curio Collection by Hilton
Terrace/patio
Embassy Suites by Hilton Huntsville

Embassy Suites by Hilton Huntsville

Embassy Suites by Hilton Huntsville
3.5 star property
Quigley, 1.1 km from Medical District
8.2 out of 10, Very Good, (1003)
"Great staff, clean room, easy check in, perfect location "
United States
Jameshia
The price is ￥17,774
￥20,751 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Embassy Suites by Hilton Huntsville
Exterior
Woodspring Suites Huntsville - Research Park

Woodspring Suites Huntsville - Research Park

Woodspring Suites Huntsville - Research Park
2.5 star property
7.3 km from Medical District
8.2 out of 10, Very Good, (236)
"Room was spotless and the staff was very nice"
United States
Martha
The price is ￥10,916
￥12,865 total
includes taxes & fees
Dec 26 - Dec 27
Woodspring Suites Huntsville - Research Park
Terrace/patio
Hampton Inn & Suites Huntsville/Research Park Area

Hampton Inn & Suites Huntsville/Research Park Area

Hampton Inn & Suites Huntsville/Research Park Area
3.0 star property
9.1 km from Medical District
9.2 out of 10, Wonderful, (924)
"Great property all around."
United States
Melissa
The price is ￥15,217
￥17,811 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Hampton Inn & Suites Huntsville/Research Park Area
Standard Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave | Desk, blackout drapes, iron/ironing board, free cribs/infant beds
Best Western Plus Madison-Huntsville Hotel

Best Western Plus Madison-Huntsville Hotel

Best Western Plus Madison-Huntsville Hotel
3.0 star property
17 km from Medical District
8.0 out of 10, Very Good, (1001)
"I like staying at this location due to being close to the airport and the great breakfast by the culinary chef who cooks from Wednesday through Sunday! "
United States
Sabra
The price is ￥9,707
￥11,476 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Best Western Plus Madison-Huntsville Hotel
Bed sheets
Studio 6 Huntsville, Al University Drive

Studio 6 Huntsville, Al University Drive

Studio 6 Huntsville, Al University Drive
2.0 star property
4 km from Medical District
8.0 out of 10, Very Good, (95)
"Staff is super nice, good sound insulation."
United States
Killian
The price is ￥11,070
￥13,043 total
includes taxes & fees
Dec 27 - Dec 28
Studio 6 Huntsville, Al University Drive
Seasonal outdoor pool
Hyatt Place Huntsville/ Research Park/ Redstone

Hyatt Place Huntsville/ Research Park/ Redstone

Hyatt Place Huntsville/ Research Park/ Redstone
3.0 star property
8.9 km from Medical District
8.8 out of 10, Excellent, (1000)
"Very nice and quite"
United States
Brenda
The price is ￥16,374
￥19,141 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hyatt Place Huntsville/ Research Park/ Redstone
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Medical District

Find the best Medical District areas and neighborhoods for the activities you enjoy most.

Priceville

Priceville is noteworthy for its restaurants, and you can make a stop at top attractions like Wheeler National Wildlife Refuge and Priceville Town Hall.

Huntsville featuring a park

Quigley

If you're spending some time in Quigley, Big Spring Park and Von Braun Center are top sights worth seeing.

Providence

Though Providence might not have many top sights, you can venture to the surrounding area to see attractions like Westside Center and MidCity Huntsville.

Old Town Huntsville

If you're looking for some top things to see and do in Old Town Huntsville and surrounding area, you can visit Huntsville Museum of Art and Big Spring Park.

Hampton Cove

While Hampton Cove isn't home to many top sights, Hampton Cove Golf Course and Madison County Nature Trail-Green Mountain are some notable places to visit nearby.

Top Medical District Hotel Reviews

Hyatt Place Huntsville/ Research Park/ Redstone

Hyatt Place Huntsville/ Research Park/ Redstone

10/10 Excellent
"Great place to stay! Very nice rooms! Beds and pillows are very comfy! Tvs are small and limited channels. "
brad 1-night trip
Posted 18 hours ago
Hyatt Place Huntsville/ Research Park/ Redstone

Frequently asked questions

What's it like in Medical District?
Travelers to the Medical District neighborhood in Huntsville will be sure to enjoy their stay. Consider a visit to Land Trust of North Alabama as part of your Medical District travel plans.
If I need to cancel my hotel reservation in Medical District, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If your reservation is non-refundable, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then filter by "fully refundable" to get top deals in Medical District.
Where can I learn more about changing or cancelling my trip to Medical District?
For more information about updating your trip to Medical District or cancelling it, go to https://www.expedia.com/service/.
What can I see and do in this Huntsville neighborhood?
Land Trust of North Alabama is an attraction you might want to check out while you're in Medical District. Huntsville-Madison County Public Library and Early Works Childrens Museum are also worth a visit when you're out sightseeing in Huntsville.