The Best Hotels Closest to Main Street Hyannis in Hyannis for 2026

Our top choices for Main Street Hyannis hotels

Hyannis Travel Inn

0.2 km from Main Street Hyannis

Jason

￥17,604 total

includes taxes & fees

Jun 1 - Jun 2

Anchor In Distinctive Waterfront Lodging

0.6 km from Main Street Hyannis

Susan

￥53,548 total

includes taxes & fees

Jun 10 - Jun 11

Green Harbor Resort

2.1 km from Main Street Hyannis

Lisa

￥47,516 total

includes taxes & fees

Jun 7 - Jun 8

Single Room | Iron/ironing board, free WiFi, bed sheets

SeaCoast Inn

0.1 km from Main Street Hyannis

Colin

￥19,370 total

includes taxes & fees

Jun 4 - Jun 5

Uncommoner Hotel by Reverie Boutique Collection

1.9 km from Main Street Hyannis

Ming Da

￥28,038 total

includes taxes & fees

Jun 8 - Jun 9

Cape Cod Inn

0.2 km from Main Street Hyannis

Maureen

￥18,410 total

includes taxes & fees

Jun 1 - Jun 2

Heritage House Inn on Cape Cod, an Ascend Collection Hotel

0.3 km from Main Street Hyannis

Angela

￥27,159 total

includes taxes & fees

Jun 3 - Jun 4

Courtyard By Marriott Cape Cod Hyannis

1.7 km from Main Street Hyannis

Bruce

￥39,010 total

includes taxes & fees

Jun 7 - Jun 8

Courtyard Resort

0.3 km from Main Street Hyannis

PERRY

￥27,161 total

includes taxes & fees

Jun 1 - Jun 2

Indoor pool, seasonal outdoor pool, pool umbrellas, sun loungers

Hampton Inn & Suites Cape Cod-West Yarmouth

1.7 km from Main Street Hyannis

Shannon

￥25,279 total

includes taxes & fees

Jun 7 - Jun 8

Bayside Resort Hotel

2.3 km from Main Street Hyannis

Christine

￥32,994 total

includes taxes & fees

Jun 7 - Jun 8

Fairfield Inn & Suites by Marriott Cape Cod Hyannis

2.3 km from Main Street Hyannis

Kenneth

￥36,274 total

includes taxes & fees

Jun 7 - Jun 8

Doubletree by Hilton Cape Cod - Hyannis

0.9 km from Main Street Hyannis

Denise

￥37,822 total

includes taxes & fees

Jun 7 - Jun 8

Comfort Inn Hyannis - Cape Cod

0.3 km from Main Street Hyannis

Andrea

￥24,563 total

includes taxes & fees

Jun 8 - Jun 9

Cape Sands Inn

1.9 km from Main Street Hyannis

Dakota

￥13,410 total

includes taxes & fees

Jun 3 - Jun 4

Hyannis Harbor Hotel

0.6 km from Main Street Hyannis

Zhaneta

￥28,758 total

includes taxes & fees

Jun 4 - Jun 5

Indoor pool, seasonal outdoor pool, sun loungers

Americas Best Value Inn & Suites Hyannis Cape Cod

0.5 km from Main Street Hyannis

Celvin

￥19,869 total

includes taxes & fees

Jun 1 - Jun 2

Holiday Inn Hyannis by IHG

2.9 km from Main Street Hyannis

Sharon

￥26,979 total

includes taxes & fees

Jun 7 - Jun 8

Room, 1 King Bed | Desk, iron/ironing board, free cribs/infant beds, rollaway beds

Hyannis Host Inn

1.6 km from Main Street Hyannis

Taneisha

￥16,423 total

includes taxes & fees

Jun 7 - Jun 8

Sunbird Cape Cod Resort

2.3 km from Main Street Hyannis

marisa

￥19,701 total

includes taxes & fees

Jun 2 - Jun 3

View all properties

Compare popular hotels close to Main Street Hyannis

Property	Star rating	Guest rating
Hyannis Travel Inn	2.5 star property	9.6 Exceptional 1,010 reviews	View
Anchor In Distinctive Waterfront Lodging	3.0 star property	9.4 Exceptional 1,000 reviews	View
Green Harbor Resort	3.0 star property	9.6 Exceptional 351 reviews	View
SeaCoast Inn	2.0 star property	9.0 Wonderful 768 reviews	View
Uncommoner Hotel by Reverie Boutique Collection	3.0 star property	9.4 Exceptional 157 reviews	View

Top Main Street Hyannis Hotel Reviews

Hyannis Plaza Hotel

10/10 Excellent

"Great location on main street able to walk to many shops and restaurants"

Cape Sands Inn

8/10 Good

"This is a two-star motel. My good rating is based on it being a two-star facility. It was what I expected for what I paid. If you are expecting five-star service and amenities, this is not the place for you. It is an older building that could use updating and a deep cleaning but the location is perfect, right in the middle of the Cape. Our room was quiet, safe and parking was ample. The pool and hot tub were clean. Room service is supposed to take place every 3 days but I think you have to ask for it. We were there for 5 nights. We didn't know we had to proactively ask for room service but we didn't mind because we were rarely in the room. We were out having fun. The staff seemed polite and friendly. There is a refrigerator but no microwave in the room. There is a community microwave in the recreation room. It was clean and we used it several times to warm up left over food and had our lunch at the picnic tables outside. I would recommend if you're just looking to have a comfortable place to sleep at night while you explore the Cape during the day."

Margaritaville Resort Cape Cod

10/10 Excellent

"First time attending Margaritaville with my family for my son’s birthday and it was amazing. The water park experience was great. Unfortunately it was raining so we were unable to use the outdoor pool. Loved the s’mores setup they had for guest to cozy up next to the fireplace with a delicious treat. The outdoor space was relaxing and I loved that they had game setup outside for kids and adults. All and all my kids really enjoyed the stay, from my 11 year old birthday boy to my 23 year old. The island vibes, along with the friendly and welcoming staff really elevated our experience! I would definitely recommend and I plan to return with my family and friends."

Hyannis Harbor Hotel

4/10 Poor

"I rarely leave negative reviews, but our experience here was disappointing enough that I feel obligated to share it. On our first full day, my fiancée and I left the room around 10:00 AM. When we returned at approximately 3:00 PM, the room still had not been cleaned. At 3:20 PM, we called the front desk and specifically requested housekeeping. We were assured the room would be serviced, and because we wanted to be accommodating, we left the room again so housekeeping could access it. We even received a callback confirming the request. We spent the next hour and a half on the patio waiting, assuming the room was being cleaned. Around 4:45 PM, I checked the room and found that nothing had been done. At 5:00 PM, I spoke with the front desk, where an employee confirmed a housekeeping request had been entered around 3:30 PM and said someone would be there shortly. At that point, the situation became stressful because we had dinner reservations and needed to get ready. The room was finally cleaned around 5:30 PM—more than two hours after our initial request. Later that evening, we asked for a couple of bottles of water and were told that guests only receive two complimentary bottles for their entire stay and must purchase any additional water from the vending machine. Fortunately, another employee, whom I believe was named Nick, stepped in and was extremely helpful. The bathroom also felt less than clean, and the shower caddy was visibly rusty. Spend extra $ if staying in Hyann"

Bayside Resort Hotel

6/10 Okay

"Whilst this hotel was extremely clean, spacious and had a brilliant pool and beach area it is extremely dated. The hallway smelt, the decor is dark brown and awful pine furniture. There was no safe in the bedrooms which as a non US traveller is a must. Only 2 towels were provided for 3 people, no bathroom mat and no hand towel. The air con whilst worked was loud and cumbersome. Breakfast had no fresh fruit and every thing had to be put into a single use bowl, plate, you name it."

Hotels near other Main Street Hyannis attractions

John F. Kennedy Hyannis Museum

4.4/5 (444 reviews)

Learn about the 35th president of the United States at this revealing museum, which is just a short distance from the Kennedy Compound.

See properties

Frequently asked questions

What's the area like around Main Street Hyannis?

Main Street Hyannis is located in a walkable area of Hyannis known for its top seafood restaurants and major shopping area. If you're looking for a convenient place to stay, check out the 192 hotels and other accommodations you'll find within a mile.

What's the best hotel to stay near Main Street Hyannis?

Adjacent to Main Street Hyannis, Hyannis Travel Inn is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an outdoor pool. Other good options within a short distance include Anchor In Distinctive Waterfront Lodging and Heritage House Inn on Cape Cod, an Ascend Collection Hotel.

How many hotels can I expect to find close to Main Street Hyannis?

Expedia has 192 hotels and other accommodations within a mile from Main Street Hyannis.

If I need to cancel the hotel reservation for my stay near Main Street Hyannis, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a reservation that's non-refundable, you might be able to cancel it and get a refund within a 24-hour period of booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to view top deals close to Main Street Hyannis.

Where can I learn more about changing or cancelling my trip in the area near Main Street Hyannis?

For more information about updating your stay near Main Street Hyannis or cancelling it, click here.

What can I see and do near Main Street Hyannis?

John F. Kennedy Hyannis Museum, Whydah Pirate Museum, and Edward Gorey House feature captivating exhibits. Hyannis Harbor, Sandy Neck Lighthouse, and West Parish Meetinghouse are landmarks that you won't want to miss. Local parks like Lewis Bay, Barnstable Dog Park, and Dennis Pond Conservation Area are peaceful spots to stop and take in some fresh air.

Find hotels near Main Street Hyannis, Hyannis from ￥13,410

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Our top choices for Main Street Hyannis hotels

Hyannis Travel Inn

Anchor In Distinctive Waterfront Lodging

Green Harbor Resort

SeaCoast Inn

Uncommoner Hotel by Reverie Boutique Collection

Cape Cod Inn

Heritage House Inn on Cape Cod, an Ascend Collection Hotel

Courtyard By Marriott Cape Cod Hyannis

Courtyard Resort

Hampton Inn & Suites Cape Cod-West Yarmouth

Bayside Resort Hotel

Fairfield Inn & Suites by Marriott Cape Cod Hyannis

Doubletree by Hilton Cape Cod - Hyannis

Comfort Inn Hyannis - Cape Cod

Cape Sands Inn

Hyannis Harbor Hotel

Americas Best Value Inn & Suites Hyannis Cape Cod

Holiday Inn Hyannis by IHG

Hyannis Host Inn

Sunbird Cape Cod Resort

Compare popular hotels close to Main Street Hyannis

Top Main Street Hyannis Hotel Reviews

Hyannis Plaza Hotel

Hotels near other Main Street Hyannis attractions

John F. Kennedy Hyannis Museum

Frequently asked questions