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Find hotels in Main Street Fort Pierce, Fort Pierce

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Our top choices for Main Street Fort Pierce hotels

Marina
The Old Apartment

The Old Apartment

The Old Apartment
4.0 star property
Main Street Fort Pierce
The price is ￥30,617
￥60,520 total
includes taxes & fees
Jan 7 - Jan 8, 2026
The Old Apartment
Exterior
At Home Inn

At Home Inn

At Home Inn
2.5 star property
8.2 km from Main Street Fort Pierce
8.0 out of 10, Very Good, (1010)
"Staff was very friendly and informative."
United States
Mary
The price is ￥8,760
￥9,811 total
includes taxes & fees
Dec 25 - Dec 26
At Home Inn
Sundeck
Prestige Hotel Vero Beach

Prestige Hotel Vero Beach

Prestige Hotel Vero Beach
2.0 star property
20.5 km from Main Street Fort Pierce
8.4 out of 10, Very Good, (1002)
"Great place"
United States
Rosa
The price is ￥20,139
￥22,556 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Prestige Hotel Vero Beach
Reception
Tru by Hilton Port St. Lucie Tradition

Tru by Hilton Port St. Lucie Tradition

Tru by Hilton Port St. Lucie Tradition
2.5 star property
23.6 km from Main Street Fort Pierce
9.2 out of 10, Wonderful, (758)
" I’ve stayed twice and it’s been an excellent experience. Clean facilities and great staff. "
United States
Daniel
The price is ￥14,781
￥16,555 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Tru by Hilton Port St. Lucie Tradition
Outdoor spa tub
Hutchinson Island Hotel

Hutchinson Island Hotel

Hutchinson Island Hotel
2.5 star property
3.1 km from Main Street Fort Pierce
8.4 out of 10, Very Good, (1353)
"The breakfast and view is the best!"
United States
Marisa
The price is ￥22,452
￥26,028 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Hutchinson Island Hotel
Bar (on property)
The Lucie

The Lucie

The Lucie
3.0 star property
23.6 km from Main Street Fort Pierce
9.0 out of 10, Wonderful, (1002)
"Great stay, excellent staff. "
United States
Steve
The price is ￥26,632
￥35,978 total
includes taxes & fees
Dec 25 - Dec 26
The Lucie
Exterior
Hampton Inn & Suites Stuart-North

Hampton Inn & Suites Stuart-North

Hampton Inn & Suites Stuart-North
2.5 star property
26.1 km from Main Street Fort Pierce
8.8 out of 10, Excellent, (1001)
"Staff warm and friendly and helpful with local spots to visit! "
United States
CHRISTY
The price is ￥20,457
￥22,809 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Hampton Inn & Suites Stuart-North
On the beach, sun loungers, beach umbrellas, beach towels
Hutchinson Shores Resort & Spa

Hutchinson Shores Resort & Spa

Hutchinson Shores Resort & Spa
4.0 star property
25.2 km from Main Street Fort Pierce
9.4 out of 10, Exceptional, (1000)
"Room was clean and comfortable, staff was very kind and helpful, I will definitely visit again "
United States
Andrekiss
The price is ￥37,178
￥48,448 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Hutchinson Shores Resort & Spa
Outdoor pool, pool umbrellas, sun loungers
The Caribbean Court Boutique Hotel

The Caribbean Court Boutique Hotel

The Caribbean Court Boutique Hotel
3.0 star property
20.6 km from Main Street Fort Pierce
9.2 out of 10, Wonderful, (862)
"Quiet, extremely clean, super helpful staff, nice pool, and very comfortable bed. Convenient to have restaurant on property. Great place for a couples getaway. "
United States
Jeffrey
The price is ￥17,598
￥19,710 total
includes taxes & fees
Jan 5 - Jan 6, 2026
The Caribbean Court Boutique Hotel
Breakfast, lunch, dinner served; American cuisine, beach views
Ocean Breeze Inn Vero Beach

Ocean Breeze Inn Vero Beach

Ocean Breeze Inn Vero Beach
3.5 star property
23.2 km from Main Street Fort Pierce
8.6 out of 10, Excellent, (1092)
"Love love this place! Most definitely will be back! "
United States
Silvia
The price is ￥22,326
￥25,005 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Ocean Breeze Inn Vero Beach
Desk, free WiFi, bed sheets
Home2 Suites by Hilton Stuart

Home2 Suites by Hilton Stuart

Home2 Suites by Hilton Stuart
3.0 star property
25.6 km from Main Street Fort Pierce
9.4 out of 10, Exceptional, (607)
"Love staying here. The staff are wonderful, the rooms are clean and the breakfast is decent with lots of options. "
United States
Heather
The price is ￥20,461
￥22,814 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Home2 Suites by Hilton Stuart
Property amenity
Fairfield Inn & Suites by Marriott Fort Pierce

Fairfield Inn & Suites by Marriott Fort Pierce

Fairfield Inn & Suites by Marriott Fort Pierce
2.5 star property
7.7 km from Main Street Fort Pierce
8.6 out of 10, Excellent, (1000)
"everything was clean and the breakfast was great"
United States
Jim
The price is ￥14,519
￥16,262 total
includes taxes & fees
Dec 28 - Dec 29
Fairfield Inn & Suites by Marriott Fort Pierce
Property amenity
Staybridge Suites Vero Beach by IHG

Staybridge Suites Vero Beach by IHG

Staybridge Suites Vero Beach by IHG
3.0 star property
24.1 km from Main Street Fort Pierce
9.8 out of 10, Exceptional, (574)
"I would definitely stay at this place again great people great atmosphere very clean"
United States
Kristi
The price is ￥20,397
￥22,844 total
includes taxes & fees
Dec 26 - Dec 27
Staybridge Suites Vero Beach by IHG
Outdoor pool, sun loungers
Best Western Downtown Stuart

Best Western Downtown Stuart

Best Western Downtown Stuart
3.0 star property
29.8 km from Main Street Fort Pierce
8.6 out of 10, Excellent, (1001)
"Nice hotel for the money"
United States
Rosemary
The price is ￥18,285
￥20,479 total
includes taxes & fees
Dec 30 - Dec 31
Best Western Downtown Stuart
Free daily on-the-go breakfast
Hotel Flamingo Inn & Suites Vero Beach I-95

Hotel Flamingo Inn & Suites Vero Beach I-95

Hotel Flamingo Inn & Suites Vero Beach I-95
2.5 star property
28.6 km from Main Street Fort Pierce
7.6 out of 10, Good, (1000)
"Clean room convenient decent breakfast "
United States
Andrew
The price is ￥10,538
￥11,803 total
includes taxes & fees
Dec 30 - Dec 31
Hotel Flamingo Inn & Suites Vero Beach I-95
Lobby
La Quinta Inn & Suites by Wyndham Ft. Pierce

La Quinta Inn & Suites by Wyndham Ft. Pierce

La Quinta Inn & Suites by Wyndham Ft. Pierce
3.0 star property
7.9 km from Main Street Fort Pierce
8.0 out of 10, Very Good, (1001)
"My stay was great, very happy."
United States
Robert
The price is ￥15,604
￥17,476 total
includes taxes & fees
Dec 30 - Dec 31
La Quinta Inn & Suites by Wyndham Ft. Pierce
Outdoor pool, sun loungers
Hampton Inn Vero Beach

Hampton Inn Vero Beach

Hampton Inn Vero Beach
2.5 star property
28.7 km from Main Street Fort Pierce
8.8 out of 10, Excellent, (1004)
"Great place to stay! Sabrina at check-in was amazing! I would definitely recommend staying here. "
United States
Troy
The price is ￥14,616
￥16,369 total
includes taxes & fees
Dec 29 - Dec 30
Hampton Inn Vero Beach
Courtyard
Star Suites: An Extended Stay Hotel

Star Suites: An Extended Stay Hotel

Star Suites: An Extended Stay Hotel
2.5 star property
24.3 km from Main Street Fort Pierce
9.6 out of 10, Exceptional, (584)
"Was perfect for our trip, will stay again! "
United States
Christopher
The price is ￥17,400
￥19,488 total
includes taxes & fees
Dec 25 - Dec 26
Star Suites: An Extended Stay Hotel
Terrace/patio
Home2 Suites by Hilton Ft. Pierce I-95

Home2 Suites by Hilton Ft. Pierce I-95

Home2 Suites by Hilton Ft. Pierce I-95
3.0 star property
7.8 km from Main Street Fort Pierce
9.4 out of 10, Exceptional, (165)
"Convenient location and good breakfast "
United States
Bruce
The price is ￥18,891
￥21,158 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Home2 Suites by Hilton Ft. Pierce I-95
3 outdoor pools, open 7:00 AM to 10:00 PM, pool umbrellas, sun loungers
Marriott Hutchinson Island Resort & Beach Villas, Golf & Marina

Marriott Hutchinson Island Resort & Beach Villas, Golf & Marina

Marriott Hutchinson Island Resort & Beach Villas, Golf & Marina
4.0 star property
29.8 km from Main Street Fort Pierce
8.2 out of 10, Very Good, (397)
"The room was awesome and the location was great. "
United States
Robin
The price is ￥33,254
￥44,073 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Marriott Hutchinson Island Resort & Beach Villas, Golf & Marina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Main Street Fort Pierce

Find the best Main Street Fort Pierce areas and neighborhoods for the activities you enjoy most.

Lakewood Park

While Lakewood Park isn't home to many top sights, Lakewood Park Regional Park / Pool and Indrio Road Park / Schoolhouse are some notable places to visit nearby.

Spanish Lakes Country Club Village

While there might not be top attractions in Spanish Lakes Country Club Village, you can explore the larger area and discover places like Lakewood Park Regional Park / Pool and McKee Botanical Garden.

Spanish Lakes Fairways

While Spanish Lakes Fairways might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Lakewood Park Regional Park / Pool and Indrio Road Park / Schoolhouse.

Meadowood

If you're looking for some top things to see and do in Meadowood and surrounding area, you can visit Endless Summer Vineyard & Winery and Lakewood Park Regional Park / Pool.

Panther Woods

If you're looking for some top things to see and do in Panther Woods and surrounding area, you can visit Endless Summer Vineyard & Winery and Indrio Road Park / Schoolhouse.

Top Main Street Fort Pierce Hotel Reviews

Star Suites: An Extended Stay Hotel

Star Suites: An Extended Stay Hotel

10/10 Excellent
"Parking was easy and secured, check-in was smooth and staff were great."
Daniel 1-night trip
Posted 4 days ago
Star Suites: An Extended Stay Hotel

Frequently asked questions

What is Main Street Fort Pierce like?
Main Street Fort Pierce is a neighborhood that travelers like for its waterfront, art, and shopping. Be sure to check out Downtown Fort Pierce and Sunrise Theater as part of your Main Street Fort Pierce travel plans.
How many hotels can I expect to find in Main Street Fort Pierce?
Book one of Expedia's 5 hotels and other accommodations in Main Street Fort Pierce and start exploring everything Fort Pierce has to offer.
If I need to cancel my hotel reservation in Main Street Fort Pierce, will I receive a refund?
Yes! The majority of hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then use the filter option "fully refundable" to review the top deals on offer in Main Street Fort Pierce.
Where can I learn more about changing or cancelling my trip to Main Street Fort Pierce?
For additional details about changing or cancelling your trip to Main Street Fort Pierce, head over to our customer service page.
What is there to do in this Fort Pierce neighborhood?
For cultural attractions in Main Street Fort Pierce, head to Sunrise Theater, Art Mundo, and Official Highwaymen Art Gallery. Downtown Fort Pierce and Fort Pierce City Marina are also a couple of places to visit in the neighborhood. A few places to visit in the area around Main Street Fort Pierce include Fort Pierce Farmer's Market, Manatee Education and Observation Center, and House of Seven Gables. A.E. Backus Museum and Marina at Fort Pierce are also worth a visit when you're out sightseeing in Fort Pierce.