La Mesa Vacations from ￥411,981

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The Latest La Mesa Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Las Americas Golden Tower Panama

Las Americas Golden Tower Panama

4 out of 5
San Francisco
Price was ￥462,640, price is now ￥411,981 per person
￥411,981
per person
Oct 21 - Oct 27
found 15 hours ago
Roundtrip flight included
Tokyo (TYO) to Panama City (PTY)
9/10 Wonderful! (1,068 reviews)

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Price was ￥692,680, price is now ￥448,944 per person
￥448,944
per person
Oct 21 - Oct 27
found 15 hours ago
Roundtrip flight included
Tokyo (TYO) to Panama City (PTY)
9.2/10 Wonderful! (1,000 reviews)
Everything was pretty awesome. The pool and surrounding area was a little small and disappointing, but still it was a great temperature and seemed clean. The gym was great with clean equipment in good condition. The included breakfast was great with lots of options and great service. I didn't use the spa or dine at the bistro, but it seemed ok. Amazing shops and restaurants all around. Overall, I would stay there again.

Reviewed on Aug 5, 2026

Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
San Francisco
Price was ￥608,075, price is now ￥456,112 per person
￥456,112
per person
Oct 21 - Oct 27
found 15 hours ago
Roundtrip flight included
Tokyo (TYO) to Panama City (PTY)
8.4/10 Very Good! (1,621 reviews)

Hyatt Regency Panama City

Hyatt Regency Panama City

5 out of 5
Bella Vista
Price was ￥492,707, price is now ￥424,885 per person
￥424,885
per person
Oct 21 - Oct 27
found 15 hours ago
Roundtrip flight included
Tokyo (TYO) to Panama City (PTY)
9.6/10 Exceptional! (386 reviews)
Great atmosphere. Staff was very helpful when asking for directions and information, some more than others. Everything was clean. I really liked this hotel and my stay.

Reviewed on Aug 4, 2026

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4 out of 5
Price was ￥477,002, price is now ￥420,488 per person
￥420,488
per person
Oct 21 - Oct 27
found 15 hours ago
Roundtrip flight included
Tokyo (TYO) to Panama City (PTY)
8.4/10 Very Good! (1,816 reviews)

Find the Best La Mesa Vacation Packages

La Mesa Hotel Deals

Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
Fully refundable
The price is ￥21,285 per night from Sep 6 to Sep 7
￥21,285
￥24,454 total
Sep 6 - Sep 7
includes taxes & fees
8.6/10 Excellent! (2,635 reviews)
"There was obviously water damage to the room the bathroom door was swollen and hard to open and close. The shower door would not open or close and the room smelled musty and was extremely humid."

Reviewed on Aug 5, 2026

Crowne Plaza Panama Airport by IHG
Aloft by Marriott Panama

Aloft by Marriott Panama

3.5 out of 5
Via Israel & Calle 76 Panama City Panama
Fully refundableReserve now, pay when you stay
The price is ￥18,731 per night from Aug 14 to Aug 15
￥18,731
￥20,604 total
Aug 14 - Aug 15
includes taxes & fees
8.8/10 Excellent! (1,005 reviews)
"Nice"

Reviewed on Aug 5, 2026

Aloft by Marriott Panama
Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall

4 out of 5
Avenida Domingo Diaz via Tocumen San Miguelito Panama
Fully refundableReserve now, pay when you stay
The price is ￥15,412 per night from Sep 4 to Sep 5
￥15,412
￥16,954 total
Sep 4 - Sep 5
includes taxes & fees
Courtyard by Marriott Panama Metromall
See all 579 properties in La Mesa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

What to do in La Mesa

Eco Agro Adventure with Horseback Riding in a Private Ranch

Eco Agro Adventure with Horseback Riding in a Private Ranch

￥12,116
per adult
Eco Agro Adventure with Horseback Riding in a Private Ranch
Amador Causeway

Private tour of Panama City and visit to the Miraflores Locks

￥10,837
per adult
100% of travellers recommend
Private tour of Panama City and visit to the Miraflores Locks
1- or 2-Nigh in Perro Chico Island, San Blas Guna Ayala

1- or 2-Nigh in Perro Chico Island, San Blas Guna Ayala

￥40,472
per adult
1- or 2-Nigh in Perro Chico Island, San Blas Guna Ayala
See all activities in La Mesa

Frequently asked questions

How much does a La Mesa vacation package cost?
You'll find cheap prices from ￥411,981 on Expedia for your La Mesa getaway. However, a range of factors like the length of stay, hotel choice and season will influence how much your vacation to La Mesa costs.
What are the cheapest months to go to La Mesa?
September, October and November are the best times to look for cheap La Mesa vacation packages. Opting to travel in less busy periods means you'll typically find better prices on hotels and flights.
How many days is enough for La Mesa?
Generally, a handful of days is enough to see the top attractions during your La Mesa vacation. However, if you want to have some time to chill out or go on day tours, consider extending your itinerary.
How to find the best La Mesa package deals?
Start your search for a La Mesa package deal by entering your preferred travel dates and destination under our "Packages" tab. Then add some filters, like "Property type" and "Guest rating," to tailor the results to your exact style. You can also sort by "Package discount" and discover offers that come with irresistible savings. If you don't find the perfect La Mesa package deal straight away, just switch up your dates and search again. Bear in mind that deals are only available for a limited time, so book early and get your La Mesa escape off to a flying start.
Is it cheaper to book a La Mesa vacation as a package?
An Expedia vacation package could score you significant savings when compared to booking stays and flights separately. Better still, you can customize your La Mesa trip to match your exact needs. Choose your preferred flight time, select the hotel type and add a rental car. Explore our bundles to see how much you can save.
When to book a vacation package to La Mesa?
If you've got your La Mesa travel dates confirmed, book as early as you can to grab some fantastic deals. With Expedia, you can typically reserve some flights up to a year in advance. Prefer spur-of-the-moment getaways? Our last-minute deals are great for impromptu escapes.
How to plan a trip to La Mesa?

  1. Pick the perfect time to travel: Your schedule, favorite season and the type of weather you like can all influence your decision on when to travel to La Mesa.
  2. Set your budget: Consider costs like flights, food and transportation when calculating how much to save for your trip to La Mesa. Then, select a hotel that suits your budget, whether that's a wallet-friendly option or a more luxurious retreat.
  3. Decide how many days away: Start by listing all the activities and sights you'd like to get to in La Mesa. Then, estimate how long you'll need for each, including any travel time.
  4. Combine your accommodations and airfare: Once you've nailed down your dates and duration, book the ideal La Mesa vacation package for you.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.