La Mesa Vacations

Book a Hotel + Flight or Car together to unlock savings

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    Better together

    Save up to ￥45,448 when you book a flight and hotel together*
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    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
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    Rest easy

    Plan, book, and manage your trip all in one place

Find the Best La Mesa Vacation Packages

La Mesa Hotel Deals

Sheraton Grand Panama
Sheraton Grand Panama
4 out of 5
Via Israel And 77th Street, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is ￥18,443 per night from Jul 25 to Jul 26
￥18,443
￥20,287 total
Jul 25 - Jul 26
includes taxes & fees
8.4/10 Very Good! (893 reviews)
"Nice hotel"

Reviewed on Jul 13, 2025

Sheraton Grand Panama
Crowne Plaza Panama Airport by IHG
Crowne Plaza Panama Airport by IHG
4 out of 5
Ave. Domingo Diaz, Corregimineto De Tocumen Hacia El, Tocumen, Panama
Fully refundable
The price is ￥16,394 per night from Jul 17 to Jul 18
￥16,394
￥18,033 total
Jul 17 - Jul 18
includes taxes & fees
8.4/10 Very Good! (2,161 reviews)
"Staff was extremely helpful. Hotel was clean. We ate appetizers in the restaurant. The Ceviche was excellent. The breakfast buffet was good and had lots of variety."

Reviewed on Jul 13, 2025

Crowne Plaza Panama Airport by IHG
Ramada Plaza By Wyndham Panama Punta Pacífica
Ramada Plaza By Wyndham Panama Punta Pacífica
4 out of 5
Via Israel y Calle 71, San Francisco, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is ￥16,542 per night from Aug 1 to Aug 2
￥16,542
￥18,196 total
Aug 1 - Aug 2
includes taxes & fees
9.4/10 Exceptional! (1,009 reviews)
"I love this hotel , first time visiting panama and everything was great , the staff are very friendly and always willing to help , just wish if the hotel had a laundry room and a microwave other than its perfect!"

Reviewed on Jul 12, 2025

Ramada Plaza By Wyndham Panama Punta Pacífica
See all 300 properties in La Mesa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

What to do in La Mesa

Eco Agro Adventure with Horseback Riding in a Private Ranch

Eco Agro Adventure with Horseback Riding in a Private Ranch

￥10,994
per adult
Eco Agro Adventure with Horseback Riding in a Private Ranch
Amador Causeway

Private tour of Panama City and visit to the Miraflores Locks

￥9,773
per adult
100% of travellers recommend
Private tour of Panama City and visit to the Miraflores Locks
Ocean to Ocean Tour in Panama Canal

Ocean to Ocean Tour in Panama Canal

￥36,163
per adult
Ocean to Ocean Tour in Panama Canal
See all activities in La Mesa

Frequently asked questions

How much does a La Mesa vacation package cost?
You'll find cheap prices on Expedia for your La Mesa getaway. However, a range of factors like the length of stay, hotel choice and season will influence how much your vacation to La Mesa costs.
What are the cheapest months to go to La Mesa?
September, October and November are the best times to look for cheap La Mesa vacation packages. Opting to travel in less busy periods means you'll typically find better prices on hotels and flights.
How many days is enough for La Mesa?
Generally, a handful of days is enough to see the top attractions during your La Mesa vacation. However, if you want to have some time to chill out or go on day tours, consider extending your itinerary.
How to find the best La Mesa package deals?
Start your search for a La Mesa package deal by entering your preferred travel dates and destination under our "Packages" tab. Then add some filters, like "Property type" and "Guest rating," to tailor the results to your exact style. You can also sort by "Package discount" and discover offers that come with irresistible savings. If you don't find the perfect La Mesa package deal straight away, just switch up your dates and search again. Bear in mind that deals are only available for a limited time, so book early and get your La Mesa escape off to a flying start.
Is it cheaper to book a La Mesa vacation as a package?
An Expedia vacation package could score you significant savings when compared to booking stays and flights separately. Better still, you can customize your La Mesa trip to match your exact needs. Choose your preferred flight time, select the hotel type and add a rental car. Explore our bundles to see how much you can save.
When to book a vacation package to La Mesa?
If you've got your La Mesa travel dates confirmed, book as early as you can to grab some fantastic deals. With Expedia, you can typically reserve some flights up to a year in advance. Prefer spur-of-the-moment getaways? Our last-minute deals are great for impromptu escapes.
How to plan a trip to La Mesa?

  1. Pick the perfect time to travel: Your schedule, favorite season and the type of weather you like can all influence your decision on when to travel to La Mesa.
  2. Set your budget: Consider costs like flights, food and transportation when calculating how much to save for your trip to La Mesa. Then, select a hotel that suits your budget, whether that's a wallet-friendly option or a more luxurious retreat.
  3. Decide how many days away: Start by listing all the activities and sights you'd like to get to in La Mesa. Then, estimate how long you'll need for each, including any travel time.
  4. Combine your accommodations and airfare: Once you've nailed down your dates and duration, book the ideal La Mesa vacation package for you.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.